Leigh Syndrome & Mitochondrial Encephalopathy Gene Panel Test
Short Name: LS & ME Gene Panel
Also known as: Mitochondrial Encephalopathy Gene Panel, Leigh Syndrome Genetic Test, Mitochondrial DNA Panel
Leigh Syndrome & Mitochondrial Encephalopathy Gene Panel Test test available at DNA Labs India for ₹36,000. Uses Next Generation Sequencing (NGS) on Amniotic fluid/ Chorionic villi/ Peripheral blood samples. Results in 4-6 weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of this test is to identify genetic mutations responsible for Leigh Syndrome and Mitochondrial Encephalopathy, enabling precise diagnosis, guiding treatment strategies, and facilitating family planning and genetic counseling.
- Test Code
- 3075
- Price
- ₹36,000
- Sample Type
- Amniotic fluid/ Chorionic villi/ Peripheral blood
- Result Time
- 4-6 weeks
- Fasting Required
- No
- Method
- Next Generation Sequencing (NGS)
Sample Collection
A doctor's prescription is required, except for surgery, pregnancy, or travel abroad cases. Ensure proper sample labeling and documentation.
Method: Venipuncture for blood, amniocentesis for amniotic fluid, chorionic villus sampling (CVS) for chorionic villi
Laboratory Analysis
Sample collection is performed by a trained phlebotomist or medical professional using sterile techniques. For blood, venipuncture is done; for amniotic fluid or CVS, specialized procedures are followed.
Report Delivery
The sample is securely packaged and transported to the laboratory under appropriate conditions for DNA extraction and analysis.
Timeline: 4-6 weeks
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to identify genetic mutations responsible for Leigh Syndrome and Mitochondrial Encephalopathy, enabling precise diagnosis, guiding treatment strategies, and facilitating family planning and genetic counseling.
How to Prepare
- For peripheral blood: Collect in EDTA vacutainer (3 ml)
- For amniotic fluid: Use a sterile container
- For chorionic villi: Place in sterile normal saline container
- Maintain cool pack during transport
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"This gene panel is crucial for early diagnosis of mitochondrial disorders, enabling timely management and informed family planning decisions."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted sample
- Insufficient sample volume
- Unlabeled or mislabeled sample
- Contaminated container
Understanding Your Results
Positive
Pathogenic variant detected, confirming diagnosis of Leigh Syndrome or Mitochondrial Encephalopathy
Negative
No pathogenic variants detected in the analyzed genes; clinical correlation recommended
Variant of Uncertain Significance (VUS)
Genetic variant identified but clinical significance is unknown; further testing or family studies may be needed
Consult a geneticist or neurologist if symptoms persist, worsen, or if there is a family history of mitochondrial disorders. Genetic counseling is recommended for positive results.
Limitations
- ⚠May not detect all possible mutations
- ⚠Variants of uncertain significance (VUS) may be identified
- ⚠Does not rule out other genetic or non-genetic causes
Risks & Considerations
- ●Minimal risk for blood draw: bruising, infection
- ●For amniocentesis/CVS: risk of miscarriage, infection, or injury to fetus
Interfering Factors
- ●Sample contamination
- ●Degraded DNA
- ●Hemolyzed blood sample
Frequently Asked Questions
What is the Leigh Syndrome & Mitochondrial Encephalopathy Gene Panel?
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Is home sample collection available?
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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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