Leucocyte Adhesion Deficiency (LAD I & II) Test
Short Name: LAD Test
Also known as: LAD Genetic Test, Leucocyte Adhesion Deficiency Flow Cytometry Test
Leucocyte Adhesion Deficiency (LAD I & II) Test test available at DNA Labs India for ₹5,500. Uses Flow Cytometry, Genetic Sequencing on Whole blood in EDTA tube and Sodium Heparin tube samples. Results in Report available next working day after sample receipt.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of this test is to diagnose Leucocyte Adhesion Deficiency (LAD I & II) by evaluating white blood cell function and identifying genetic mutations, aiding in early intervention and management of the disorder.
- Test Code
- 1180
- Price
- ₹5,500
- Sample Type
- Whole blood in EDTA tube and Sodium Heparin tube
- Result Time
- Report available next working day after sample receipt.
- Fasting Required
- No
- Method
- Flow Cytometry, Genetic Sequencing
Sample Collection
Provide clinical details and a recent CBC report. No fasting required, but specify time of draw on the test request form.
Method: Venipuncture
Laboratory Analysis
Standard venipuncture procedure with blood drawn into EDTA and Sodium Heparin tubes, mixed thoroughly.
Report Delivery
Ship samples immediately at room temperature (18-22°C). Do not refrigerate or freeze.
Timeline: Report available next working day after sample receipt.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to diagnose Leucocyte Adhesion Deficiency (LAD I & II) by evaluating white blood cell function and identifying genetic mutations, aiding in early intervention and management of the disorder.
How to Prepare
- Collect 3 mL whole blood in Lavender Top (EDTA) tube
- Collect 3 mL whole blood in Green Top (Sodium Heparin) tube
- Mix tubes gently to prevent clotting
- Label tubes with patient details and time of draw
- Ship at room temperature (18-22°C) without refrigeration or freezing
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Early genetic testing for LAD I & II is crucial for managing recurrent infections and planning treatments like Hematopoietic Cell Transplantation (HCT)."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Samples received refrigerated or frozen
- Insufficient sample volume or improper tube type
- Missing clinical details or CBC report
- Hemolyzed or clotted samples
Understanding Your Results
LAD I & II unlikely; consider other causes
Consistent with LAD-I; genetic testing for ITGB2 mutation recommended
Consistent with LAD-II; genetic testing for GDP-fucose transporter mutation recommended
Confirms LAD-I diagnosis
Confirms LAD-II diagnosis
Consult a healthcare provider if you or your child experience frequent, severe infections, delayed wound healing, or other symptoms suggestive of LAD. Early diagnosis is key for effective treatment planning.
Limitations
- ⚠Test may not detect all rare genetic variants; clinical correlation is essential
- ⚠Flow cytometry requires specialized equipment and expertise
- ⚠Results should be interpreted alongside clinical history and CBC reports
Risks & Considerations
- ●Minor bruising or pain at the blood draw site
- ●Rare risk of infection or fainting during venipuncture
Interfering Factors
- ●Recent blood transfusions may affect leucocyte marker analysis
- ●Sample hemolysis or improper storage can impact flow cytometry results
- ●Concurrent infections might temporarily alter white blood cell counts
Frequently Asked Questions
What is Leucocyte Adhesion Deficiency (LAD)?
What is the cost of the LAD I & II Test at DNA Labs India?
What samples are required for this test?
Is fasting required for the LAD test?
How is LAD diagnosed?
What are the symptoms of LAD I and II?
How long does it take to get results?
Is home sample collection available?
What is the purpose of genetic testing in LAD?
Can this test detect both LAD I and II?
Is the test suitable for children?
What should I do if my test results are positive?
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Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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