Skip to main content
DNA Labs India

LMNA Gene Limb-girdle muscular dystrophy, autosomal dominant type 1B NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

LMNA Gene Limb-girdle muscular dystrophy, autosomal dominant type 1B NGS Genetic Test

Short Name: LMNA LGMD1B NGS Test

Also known as: LGMD1B, Limb-girdle muscular dystrophy type 1B, LMNA-related muscular dystrophy

LMNA Gene Limb-girdle muscular dystrophy, autosomal dominant type 1B NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in Results typically available within 3 to 4 weeks from sample receipt.. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

To detect mutations in the LMNA gene associated with limb-girdle muscular dystrophy type 1B, aiding in accurate diagnosis, genetic counseling, family planning, and personalized treatment strategies.

Test Code
1659
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
Results typically available within 3 to 4 weeks from sample receipt.
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

No specific preparation required. Inform the healthcare provider about any medications or supplements being taken.

Method: Venipuncture

Step 2

Laboratory Analysis

Blood sample will be drawn by a trained phlebotomist. Ensure proper identification and labeling of the sample.

Step 3

Report Delivery

Apply pressure to the puncture site to stop bleeding. Avoid heavy lifting or strenuous activity for a few hours.

Timeline: Results typically available within 3 to 4 weeks from sample receipt.

Patient Instructions

1
Before the Test:Genetic counseling is recommended before testing to understand implications and prepare for potential results.
2
During the Test:Sample collection and DNA extraction are performed in the laboratory using advanced NGS technology.
3
After the Test:Report is generated and shared via the chosen delivery method (online portal, email, or WhatsApp) within 3 to 4 weeks.

About This Test

Who Should Get This Test

To detect mutations in the LMNA gene associated with limb-girdle muscular dystrophy type 1B, aiding in accurate diagnosis, genetic counseling, family planning, and personalized treatment strategies.

How to Prepare

  • Follow any fasting instructions if provided
  • Bring valid ID and prescription for the test
  • Wear loose clothing to facilitate blood draw

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Early genetic testing for LMNA mutations can help in timely management and family planning for autosomal dominant disorders."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Sample Volume5 mL blood
ContainerEDTA tube
Collection MethodVenipuncture

Sample Stability

Blood sample stable at room temperature for 24 hours
Extracted DNA stable for longer periods if stored at appropriate temperatures
Sample Rejection Criteria:
  • Hemolyzed sample
  • Clotted blood
  • Unlabeled or mislabeled samples
  • Insufficient sample volume

Understanding Your Results

Results indicate the presence or absence of mutations in the LMNA gene. A positive result confirms diagnosis of LMNA-related muscular dystrophy, while a negative result may require further clinical evaluation or additional testing.
Positive: Pathogenic variant detected in the LMNA gene, confirming diagnosis of limb-girdle muscular dystrophy type 1B.
Negative: No pathogenic variants found, but clinical correlation is advised if symptoms persist.
Variant of uncertain significance (VUS): May require family studies, functional analysis, and clinical correlation for interpretation.
⚠️ When to Consult a Doctor:

If you experience persistent muscle weakness, difficulty walking, frequent falls, or have a family history of muscular dystrophy, consult a neurologist or geneticist for evaluation and possible genetic testing.

Limitations

  • ⚠May not detect all types of mutations or variants of uncertain significance
  • ⚠Requires genetic counseling for accurate interpretation
  • ⚠Not a prenatal test unless specified for specific indications

Risks & Considerations

  • ●Minimal risk from blood draw, such as bruising, soreness, or rare infection
  • ●Psychological impact of genetic results, requiring counseling support

Interfering Factors

  • ●Sample contamination
  • ●Degraded DNA
  • ●Insufficient sample volume

Frequently Asked Questions

What is LMNA Gene Limb-girdle muscular dystrophy, autosomal dominant type 1B?
It is a rare genetic disorder caused by mutations in the LMNA gene, leading to muscle weakness and wasting, primarily in the hips and shoulders.
What are the common symptoms of this disorder?
Symptoms include muscle weakness, difficulty walking, frequent falls, loss of muscle mass, pain, stiffness, and contractures.
How is the diagnosis confirmed?
Diagnosis is confirmed through genetic testing using next-generation sequencing (NGS) to detect mutations in the LMNA gene.
What is NGS technology used in this test?
NGS (next-generation sequencing) is an advanced method that analyzes the entire LMNA gene for mutations with high accuracy and reliability.
What does the test involve?
The test involves collecting a blood sample, extracting DNA, and performing NGS analysis to identify mutations in the LMNA gene.
How long does it take to get the results?
Results are typically available within 3 to 4 weeks from the time the sample is received at the laboratory.
Is home sample collection available for this test?
Yes, DNA Labs India offers free home sample collection across India for this test when booked online.
What is the cost of the LMNA gene NGS genetic test?
The cost is INR 20000, which includes sample collection, analysis, and report delivery.
Are there any risks associated with the genetic test?
The test carries minimal risks from blood draw, such as bruising, and potential psychological impact, for which genetic counseling is recommended.
How should I prepare for the test?
No special preparation is needed, but inform your doctor about any medications and bring valid ID for sample collection.
What does a positive result mean?
A positive result indicates the presence of a pathogenic LMNA mutation, confirming the diagnosis of limb-girdle muscular dystrophy type 1B.
Can this test be used for family planning?
Yes, the test can inform family planning by identifying carriers and assessing risk for offspring, with genetic counseling advised.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

Related Tests

Angelman Syndrome Test

₹10,000

Duchenne / Becker Muscular Dystrophy (DMD / BMD) Gene Mutation Test

₹14,000

Episodic Ataxia Type 1 Hotspot Test

₹11,500

Episodic Ataxia Comprehensive Profile Hotspot Test

₹16,000

Megalencephalic Leukoencephalopathy with Subcortical Cysts Van Der Knaap and Nalband MLC Gene Hotspot Mutation Test

₹7,500

Analyzer 18 SMA 18 Test Panel

₹1,755
For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

Book Your Test

Enter your details and we'll connect you within 15 minutes.

🧬

Quick Connect

Enter your mobile number and we’ll connect you with the team.

+91

✅ Connecting you now...

🔒 Your number is used to respond to this request.