Expert Panel 4 Test
Short Name: Expert Panel 4
Also known as: Expert Panel 4 Cancer Review Test, Expert Histopathology Panel 4, Expert Pathology Second Opinion Panel 4, Oncology Expert Review Panel 4
Expert Panel 4 Test test available at DNA Labs India for ₹25,000. Uses Light Microscopy, Expert Histopathological Review on Histopathology sections and/or Paraffin embedded tissue blocks or Cytology smears previously reported upon samples. Results in Sample accepted daily by 6:00 PM. Report delivered within 7 working days from the date of sample receipt at the laboratory.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The purpose of the Expert Panel 4 Test is to provide a comprehensive expert pathology review of tissue specimens for accurate cancer diagnosis. This panel examines over 20 slides and/or paraffin blocks from a single anatomic site using light microscopy to confirm or revise a cancer diagnosis, determine tumor type and grade, assess surgical margins, evaluate lymphovascular and perineural invasion, and identify features relevant to staging and prognosis. It serves as a valuable second opinion before initiating definitive cancer treatment.
- Test Code
- 1191
- CPT Code
- 88323
- ICD Code
- C80.1
- Price
- ₹25,000
- Sample Type
- Histopathology sections and/or Paraffin embedded tissue blocks or Cytology smears previously reported upon
- Result Time
- Sample accepted daily by 6:00 PM. Report delivered within 7 working days from the date of sample receipt at the laboratory.
- Fasting Required
- No
- Method
- Light Microscopy, Expert Histopathological Review
Sample Collection
Ensure all relevant histopathology slides and/or paraffin-embedded tissue blocks from the single anatomic site are gathered. Collect all previous pathology reports, clinical history, imaging reports, and treatment records to accompany the specimen. Complete the test request form with accurate patient and clinical details.
Method: Submission of existing tissue blocks and/or previously prepared slides along with prior reports and clinical history
Laboratory Analysis
Slides should be securely placed in a slide box and paraffin blocks in a sealed, padded container to prevent damage during transit. Ship at room temperature. Label all specimens clearly with patient name and identification number.
Report Delivery
After dispatch, inform DNA Labs India of the shipment details. The laboratory will acknowledge receipt of specimens. Reports will be generated within 7 working days from the date of sample receipt and delivered via online portal, email, WhatsApp, or courier as per the patient's preference.
Timeline: Sample accepted daily by 6:00 PM. Report delivered within 7 working days from the date of sample receipt at the laboratory.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the Expert Panel 4 Test is to provide a comprehensive expert pathology review of tissue specimens for accurate cancer diagnosis. This panel examines over 20 slides and/or paraffin blocks from a single anatomic site using light microscopy to confirm or revise a cancer diagnosis, determine tumor type and grade, assess surgical margins, evaluate lymphovascular and perineural invasion, and identify features relevant to staging and prognosis. It serves as a valuable second opinion before initiating definitive cancer treatment.
How to Prepare
- Submit histopathology sections and/or paraffin-embedded tissue blocks or previously reported cytology smears
- Ship all specimens at room temperature in appropriate protective packaging
- Include all previous reports, clinical history, and relevant details along with the test request form
- Ensure specimens are clearly labeled with patient identification
- Samples are accepted daily by 6:00 PM at DNA Labs India
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"The Expert Panel 4 Test provides a thorough second-opinion review of histopathology slides and tissue blocks from a single anatomic site. For patients with a confirmed or suspected cancer diagnosis, this panel allows an experienced pathologist to re-evaluate tumor type, grade, margin status, and other critical features that directly influence treatment planning. I recommend this test for patients who have had a biopsy or surgical excision and wish to confirm the diagnosis before initiating chemotherapy, radiation, or surgical intervention. Accurate pathology review is the cornerstone of effective cancer management."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Specimens received without a completed test request form
- Slides or blocks with no patient identification or labeling
- Specimens that are severely damaged, broken, or improperly packaged
- Absence of prior clinical history and previous pathology reports when required for accurate review
- Unfixed wet tissue received instead of properly processed paraffin-embedded blocks
Understanding Your Results
Favorable pathological outcome suggesting complete excision with no evidence of local invasion into vessels or nerves. Correlation with clinical staging recommended.
Tumor cells are present at one or more resection margins, indicating potential residual disease. Re-excision or additional treatment may be warranted.
Tumor cells detected within lymphatic or vascular channels, which may indicate an increased risk of metastasis and warrants further staging evaluation.
Tumor invasion along nerve pathways identified, which may have implications for local recurrence risk and treatment planning.
Poorly differentiated tumor indicating aggressive biological behavior. More intensive treatment and close follow-up may be recommended by the treating oncologist.
If the expert review differs from the original pathology report, the revised diagnosis should be discussed with the treating oncologist for treatment plan modification.
Consult your oncologist if the expert panel review identifies positive margins, lymphovascular or perineural invasion, a change in tumor type or grade compared to the original diagnosis, or if additional molecular or immunohistochemical testing is recommended. Any unexpected or discordant findings should be discussed with your treating specialist to determine the appropriate next steps in management.
Limitations
- ⚠This test is an expert review of existing histopathology slides and/or blocks; it does not involve new molecular or immunohistochemical testing unless separately requested
- ⚠Definitive staging may require correlation with clinical and radiological findings beyond the scope of this panel
- ⚠Certain rare or poorly differentiated tumors may require additional immunohistochemistry or molecular studies for definitive classification
- ⚠The review is based on the material submitted; results are dependent on the quality and representativeness of the specimen
Risks & Considerations
- ●As this test involves review of existing tissue specimens, there are no direct physical risks to the patient from the testing process itself
- ●Submitting all available slides and blocks from the site may temporarily deplete the stored specimen; discuss with your pathologist if additional testing may be needed in the future
- ●There is a small possibility that the submitted material may not be adequate for a definitive expert opinion, in which case additional specimens may be requested
Interfering Factors
- ●Improperly fixed or poorly preserved tissue specimens may compromise evaluation quality
- ●Inadequate number of slides or blocks submitted relative to the lesion size
- ●Crushed or distorted tissue from prior handling or transport damage
- ●Absence of prior clinical history and previous pathology reports may limit accurate interpretation
Compare With Similar Tests
| Test | Expert Panel 4 Test | Expert Panel 1 Test | Expert Panel 2 Test | Expert Panel 3 Test | Expert Panel 5 Test |
|---|---|---|---|---|---|
| Comparison | Expert Panel 4 Test |
Frequently Asked Questions
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