Skip to main content
DNA Labs India

Maternal Serum Screen 3 Triple Test

DNA Labs India | ISO 9001:2015 Certified

Maternal Serum Screen 3 Triple Test

Short Name: Triple Test

Also known as: Triple Screen Test, Maternal Serum Screen, Second Trimester Screening

Maternal Serum Screen 3 Triple Test test available at DNA Labs India for ₹3,159. Uses Chemiluminescent Immunoassay on Serum samples. Results in Results typically available within 24 hours.. Free home collection in 300+ cities across India.

Blood TestFemaleAdult (Pregnant Women)🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

To evaluate the risk of Down syndrome (Trisomy 21), Edward's syndrome (Trisomy 18), and open neural tube defects by measuring AFP, estriol, and hCG levels.

Test Code
1215
Price
₹3,159
Sample Type
Serum
Result Time
Results typically available within 24 hours.
Fasting Required
No
Method
Chemiluminescent Immunoassay
Step 1

Sample Collection

Provide maternal date of birth, LMP or ultrasound date, IVF status, number of fetuses, diabetic status, body weight in kg, smoking status, and previous history of Trisomy 21 pregnancy. Fill Maternal Serum Screen requisition form (Form 11).

Method: Venipuncture

Step 2

Laboratory Analysis

A healthcare professional will draw a small blood sample from a vein in your arm.

Step 3

Report Delivery

Apply pressure to the puncture site to stop bleeding. No special care is needed.

Timeline: Results typically available within 24 hours.

Patient Instructions

1
Before the Test:No specific preparation is required, but provide all necessary medical information.
2
During the Test:A simple blood draw from the arm, similar to any other blood test.
3
After the Test:You can resume normal activities immediately.

About This Test

Who Should Get This Test

To evaluate the risk of Down syndrome (Trisomy 21), Edward's syndrome (Trisomy 18), and open neural tube defects by measuring AFP, estriol, and hCG levels.

How to Prepare

  • Fast for 8-10 hours if required, but typically not necessary.
  • Wear loose clothing for easy access to the arm.
  • Inform the technician of any medications or supplements.

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"This test is an essential part of prenatal care, helping to identify high-risk pregnancies early for appropriate management."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeSerum
Sample Volume3 mL
ContainerSST (Serum Separator Tube)
Collection MethodVenipuncture

Sample Stability

Room Temperature: 2 hours
Refrigerator: 1 week
Frozen: 4 weeks
Sample Rejection Criteria:
  • Hemolyzed samples
  • Insufficient volume
  • Incorrectly labeled samples

Understanding Your Results

Results are interpreted based on the levels of AFP, estriol, and hCG, converted to Multiples of the Median (MoM) for gestational age. Abnormal levels may indicate an increased risk.
📊
📊
📊
⚠️ When to Consult a Doctor:

If test results are abnormal, consult your healthcare provider for further diagnostic testing such as amniocentesis or detailed ultrasound.

Limitations

  • ⚠Screening test only, not diagnostic
  • ⚠False positive rate of about 5%
  • ⚠Detection rate of 55-65% for Down syndrome
  • ⚠Cannot detect all chromosomal abnormalities

Risks & Considerations

  • ●Minimal risk associated with blood draw, such as bruising or infection

Interfering Factors

  • ●Multiple gestations (e.g., twins)
  • ●Maternal diabetes
  • ●Smoking
  • ●Incorrect gestational age dating
  • ●Previous history of Trisomy 21 pregnancy

Compare With Similar Tests

TestMaternal Serum Screen 3 Triple Test Test
ComparisonMaternal Serum Screen 3 Triple Test Test

Frequently Asked Questions

What is the Maternal Serum Screen 3 Triple Test?
It is a prenatal blood test that measures three substances in the mother's blood to assess the risk of certain fetal conditions.
When is the best time to take this test?
Between 15 and 20 weeks of pregnancy, ideally at 15-20 weeks.
What does the test measure?
It measures Alpha-fetoprotein (AFP), estriol, and human chorionic gonadotropin (hCG).
Is fasting required for this test?
No, fasting is not typically required for this test.
How is the sample collected?
Through a simple blood draw from a vein in the arm.
What do abnormal results mean?
Abnormal results may indicate an increased risk of Down syndrome, Edward's syndrome, or neural tube defects, but further testing is needed for confirmation.
What is the cost of the test at DNA Labs India?
The cost is INR 3159.0.
Is home sample collection available?
Yes, free home collection is available in many cities across India.
How long does it take to get the results?
Results are typically available the same day.
Can this test diagnose Down syndrome?
No, it is a screening test that indicates risk; diagnostic tests like amniocentesis are needed for confirmation.
What are the risks of the test?
The test itself has no significant risks; only minor risks associated with blood draw, like bruising.
How should I prepare for the test?
No special preparation is needed, but provide all required medical information to the lab.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

Related Tests

AFP (Alpha Fetoprotein): Amniotic Fluid Test

₹936

Pre-Eclampsia Predictor (sFLT-1

₹4,500

PAPP-A (Pregnancy Associated Plasma Protein-A) Test

₹1,053
For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

Book Your Test

Enter your details and we'll connect you within 15 minutes.

🧬

Quick Connect

Enter your mobile number and we’ll connect you with the team.

+91

✅ Connecting you now...

🔒 Your number is used to respond to this request.