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Metanephrines Fractionated 24 Hour Urine Test

DNA Labs India | ISO 9001:2015 Certified

Metanephrines Fractionated 24 Hour Urine Test

Short Name: Metanephrines 24hr Urine

Also known as: Urine Metanephrines Test, 24-Hour Urine Metanephrines

Metanephrines Fractionated 24 Hour Urine Test test available at DNA Labs India for ₹8,500. Uses HPLC with Electrochemical Detection on 50 mL (10 mL min.) aliquot of 24-hour urine samples. Results in Reports available on Friday or Tuesday following sample submission on Wednesday or Saturday.. Free home collection in 300+ cities across India.

DiagnosticAll Ages🏠 Home Collection

🩺 Medically Reviewed By

Overview

This test measures levels of metanephrines to diagnose catecholamine-secreting tumors like pheochromocytoma and paraganglioma, which can cause hypertension and other symptoms.

Test Code
1231
Price
₹8,500
Sample Type
50 mL (10 mL min.) aliquot of 24-hour urine
Result Time
Reports available on Friday or Tuesday following sample submission on Wednesday or Saturday.
Fasting Required
No
Method
HPLC with Electrochemical Detection
Step 1

Sample Collection

Avoid Alpha-Methyldopa, Buspirone, Codeine, Isoproterenol metabolite, Mandelamine, L-dopa, Paracetamol, Metoclopramide, pepper, alcoholic beverages, tea/coffee, tobacco, and strenuous exercise for at least 72 hours before and during collection.

Method: 24-hour urine collection

Step 2

Laboratory Analysis

Collect all urine for 24 hours in the provided container with preservative, store refrigerated or frozen, and record total volume.

Step 3

Report Delivery

Return the container to the laboratory promptly and resume normal activities.

Timeline: Reports available on Friday or Tuesday following sample submission on Wednesday or Saturday.

Patient Instructions

1
Before the Test:Avoid certain medications, foods, and activities 72 hours before collection as instructed.
2
During the Test:Collect urine meticulously over 24 hours following all instructions.
3
After the Test:Submit the sample to the lab and await results; no special post-test care needed.

About This Test

Who Should Get This Test

This test measures levels of metanephrines to diagnose catecholamine-secreting tumors like pheochromocytoma and paraganglioma, which can cause hypertension and other symptoms.

How to Prepare

  • Use the provided container with preservative
  • Collect urine for full 24 hours
  • Store samples refrigerated or frozen
  • Record 24-hour urine volume on the form
  • Avoid interfering substances 72 hours prior

Doctor's Notes

Reviewed by — MBBS, MD (Biochemistry) · Reg. No. 21504

"This test is essential for screening catecholamine-secreting tumors like pheochromocytoma. Always consult an oncologist for result interpretation and management."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample Type50 mL (10 mL min.) aliquot of 24-hour urine
Sample Volume50 mL (10 mL min.)
ContainerUrine container with appropriate preservative
Collection Method24-hour urine collection

Sample Stability

Room Temperature: 8 hours
Refrigerator: 5 days
Frozen: 30 days
Sample Rejection Criteria:
  • Improper collection without preservative
  • Missing volume record
  • Sample not stored correctly

Understanding Your Results

Results indicate metanephrine levels in urine; elevated levels may suggest adrenal tumors. Interpretation should be done by a healthcare professional considering clinical context.
Compare results to reference ranges
High levels may indicate pheochromocytoma or paraganglioma
Consult an oncologist for further evaluation
Repeat testing may be needed if symptoms persist
⚠️ When to Consult a Doctor:

If you experience symptoms like high blood pressure, headaches, or sweating, or if test results are abnormal, consult an oncologist immediately.

Limitations

  • Requires strict 24-hour urine collection
  • Results may be affected by medications or diet
  • Not for rapid diagnosis; use as screening test

Risks & Considerations

  • No significant risks; minimal discomfort from urine collection

Interfering Factors

  • Alpha-Methyldopa
  • Buspirone
  • Codeine
  • Isoproterenol metabolite
  • Mandelamine
  • L-dopa
  • Paracetamol
  • Metoclopramide
  • Pepper
  • Alcoholic beverages
  • Tea/coffee
  • Tobacco
  • Strenuous exercise

Frequently Asked Questions

What is the Metanephrines Fractionated 24 Hour Urine Test?
It is a diagnostic test that measures metanephrines in urine collected over 24 hours to help diagnose adrenal tumors like pheochromocytoma.
Why is this test performed?
To screen for catecholamine-secreting tumors such as pheochromocytoma and paraganglioma, which cause symptoms like high blood pressure and headaches.
What conditions can this test diagnose?
Pheochromocytoma, paraganglioma, and neuroblastoma, which are rare tumors affecting the adrenal glands or nerve cells.
How do I prepare for the test?
Avoid certain medications, foods, and activities like alcohol, coffee, and strenuous exercise for 72 hours before and during urine collection.
How is the urine sample collected?
Collect all urine for 24 hours in a provided container with preservative, store it refrigerated or frozen, and record the total volume.
What is the cost of the test?
The test costs INR 8500 at DNA Labs India, which includes home sample collection across India.
Is home collection available?
Yes, free home sample collection is available for online bookings in numerous cities across India.
How long does it take to get the results?
Results are typically available within 2 days; for example, samples submitted Wednesday or Saturday yield reports Friday or Tuesday.
What are the risks of the test?
There are no significant risks; it involves standard urine collection with minimal discomfort.
What do abnormal results mean?
Elevated metanephrine levels may indicate the presence of adrenal tumors; consult an oncologist for further evaluation and diagnosis.
Are there any dietary restrictions before the test?
Avoid pepper, alcoholic beverages, tea, and coffee for at least 72 hours before and during specimen collection.
How accurate is this test?
The test is analyzed using HPLC-EC method, ensuring high accuracy, but results should be interpreted by a healthcare professional.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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