MFF Gene Mitochondrial encephalomyopathy NGS Genetic Test
Short Name: MFF NGS Test
Also known as: MFF Gene Mitochondrial Encephalomyopathy NGS Test, MFF Mutation Analysis, Mitochondrial Encephalomyopathy Genetic Test
MFF Gene Mitochondrial encephalomyopathy NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in Reports are issued within 3 to 4 weeks after the sample reaches the laboratory.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SHAILAJA RAGHUNATH MURDESHWAR
Consultant Physician · Reg: 8052
Last reviewed: September 7, 2026
Overview
The purpose of this NGS genetic test is to detect mutations in the MFF gene that cause mitochondrial encephalomyopathy. Identifying the genetic cause helps in confirming diagnosis, estimating recurrence risk, and guiding treatment and surveillance.
- Test Code
- 4327
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- Reports are issued within 3 to 4 weeks after the sample reaches the laboratory.
- Fasting Required
- No
- Method
- Next Generation Sequencing (NGS)
Sample Collection
No fasting is required. However, a pre-test genetic counseling session is recommended and is included in the test price. Please bring any relevant medical records, prior neuroimaging, or biochemical test results, and be prepared to provide a detailed family history.
Method: Venipuncture or Fingerstick
Laboratory Analysis
Blood sample will be collected by a trained phlebotomist using venipuncture. For FTA card collection, a single drop of blood will be obtained via a simple fingerstick. The procedure is quick and minimally invasive.
Report Delivery
You can resume normal activities immediately. The sample will be securely transported to the laboratory. Results will be available in 3-4 weeks and can be accessed online or via email.
Timeline: Reports are issued within 3 to 4 weeks after the sample reaches the laboratory.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this NGS genetic test is to detect mutations in the MFF gene that cause mitochondrial encephalomyopathy. Identifying the genetic cause helps in confirming diagnosis, estimating recurrence risk, and guiding treatment and surveillance.
How to Prepare
- Fasting is not required
- Bring prior medical records and family history details
- A valid government ID and consent form for genetic testing are required
- If the patient is a minor, a parent or guardian must provide consent and accompany the child
Doctor's Notes
Reviewed by Dr SHAILAJA RAGHUNATH MURDESHWAR — MBBS, MD (General Medicine) · Reg. No. 8052
"Mitochondrial disorders often follow maternal inheritance; genetic counseling is essential for family planning and risk assessment."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted blood sample
- Incorrectly labeled sample
- Sample received more than 72 hours after collection at ambient temperature
- FTA card that is wet, moldy, or contaminated
Understanding Your Results
Positive
Pathogenic variant in the MFF gene confirms the diagnosis of MFF-related mitochondrial encephalomyopathy. Consultation with a geneticist is advised for management and recurrence risk.
Negative
No pathogenic variant identified in the MFF gene. Alternative genetic causes of mitochondrial encephalomyopathy should be considered.
Variant of Uncertain Significance
A genetic variant was found but its clinical significance is unknown. Additional family studies and functional analyses may be needed.
If you or your child experience progressive muscle weakness, unexplained seizures, developmental regression, or a family history of mitochondrial disease, consult a neurologist or clinical geneticist for evaluation and testing.
Risks & Considerations
- ●Minimal discomfort at needle site
- ●Slight bruising around the venipuncture spot
- ●Dizziness or fainting in rare cases
Interfering Factors
- ●Maternal DNA contamination in prenatal samples
- ●Extremely poor DNA quality due to hemolysis or degradation
- ●Presence of homologous pseudogenes or highly similar gene sequences
- ●Rare variants of uncertain significance that may complicate interpretation
Compare With Similar Tests
| Test | MFF Gene Mitochondrial encephalomyopathy NGS Genetic Test | |||
|---|---|---|---|---|
| Comparison | MFF Gene Mitochondrial encephalomyopathy NGS Genetic Test |
Frequently Asked Questions
What is the MFF gene mitochondrial encephalomyopathy NGS genetic test?
What is the cost of the MFF gene NGS genetic test in India?
What sample is needed for the MFF gene test?
How long does it take to get results?
Is fasting required before the test?
Will I get raw data files like FASTQ and VCF?
What does a positive test result mean?
Can this test be done on a child?
Is genetic counseling included in the test cost?
Can this test detect all types of mitochondrial encephalomyopathy?
Is home sample collection available for this test?
How should I prepare for the test?
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