Mitochondrial Encephalomyopathy Lactic Acidosis and Stroke-Like Episodes (MELAS) Mutation Detection Test
Short Name: MELAS Mutation Detection Test
Also known as: MELAS Test, MELAS Mutation Analysis, Mitochondrial DNA Test for MELAS
Mitochondrial Encephalomyopathy Lactic Acidosis and Stroke-Like Episodes (MELAS) Mutation Detection Test test available at DNA Labs India for ₹7,500. Uses PCR, Sequencing on Whole blood samples. Results in Sample accepted Monday by 9 am; report delivered by Friday via online portal, email, or WhatsApp.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
To detect mutations in mitochondrial DNA that cause Mitochondrial Encephalomyopathy Lactic Acidosis and Stroke-Like Episodes (MELAS), aiding in diagnosis and management of the condition.
- Test Code
- 1258
- Price
- ₹7,500
- Sample Type
- Whole blood
- Result Time
- Sample accepted Monday by 9 am; report delivered by Friday via online portal, email, or WhatsApp.
- Fasting Required
- No
- Method
- PCR, Sequencing
Sample Collection
Ensure the Genomics Clinical Information Requisition Form (Form 20) is duly filled. No fasting required. Inform the healthcare provider about any medications or recent procedures.
Method: Blood draw
Laboratory Analysis
A phlebotomist will collect a blood sample from a vein in the arm using a lavender top (EDTA) tube. The process is quick and minimally invasive.
Report Delivery
Apply pressure to the puncture site to prevent bruising. The sample will be refrigerated and shipped to the lab. Avoid strenuous activity with the arm used for collection.
Timeline: Sample accepted Monday by 9 am; report delivered by Friday via online portal, email, or WhatsApp.
Patient Instructions
About This Test
Who Should Get This Test
To detect mutations in mitochondrial DNA that cause Mitochondrial Encephalomyopathy Lactic Acidosis and Stroke-Like Episodes (MELAS), aiding in diagnosis and management of the condition.
How to Prepare
- Collect 4 mL (2 mL min.) of whole blood in a lavender top (EDTA) tube.
- Ship refrigerated; do not freeze.
- Include the duly filled Genomics Clinical Information Requisition Form (Form 20).
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"Genetic testing is crucial for confirming MELAS diagnosis, enabling early intervention and management of symptoms to improve quality of life."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Sample not refrigerated during transport
- Incorrect tube type or insufficient volume
- Missing or incomplete Genomics Clinical Information Requisition Form (Form 20)
- Sample hemolyzed, clotted, or contaminated
Understanding Your Results
Positive (Mutation Detected)
Confirms a genetic diagnosis of MELAS. Correlation with clinical symptoms is essential for management.
Negative (No Mutation Detected)
No common MELAS-associated mutation identified. Does not entirely rule out MELAS or other mitochondrial disorders; further testing may be recommended.
Consult a doctor if experiencing symptoms such as seizures, stroke-like episodes, muscle weakness, lactic acidosis, or neurological decline, especially in childhood or early adulthood.
Limitations
- ⚠May not detect all rare or novel mitochondrial mutations
- ⚠Results should be interpreted in conjunction with clinical findings and family history
- ⚠Cannot rule out other mitochondrial disorders without additional testing
Risks & Considerations
- ●Minor bruising or pain at the puncture site
- ●Rare risk of infection or dizziness
Interfering Factors
- ●Hemolyzed or clotted blood sample
- ●Insufficient sample volume
- ●Contamination during collection or transport
- ●Recent blood transfusion (may affect DNA analysis)
Compare With Similar Tests
| Test | Mitochondrial Encephalomyopathy Lactic Acidosis and Stroke-Like Episodes (MELAS) Mutation Detection Test | Lactic Acid Test | Muscle Biopsy | Brain MRI |
|---|---|---|---|---|
| Comparison | Mitochondrial Encephalomyopathy Lactic Acidosis and Stroke-Like Episodes (MELAS) Mutation Detection Test |
Frequently Asked Questions
What is MELAS syndrome?
Who should consider the MELAS Mutation Detection Test?
How is the test performed?
What is the cost of the MELAS test at DNA Labs India?
Is home sample collection available for this test?
How long does it take to get the results?
What does a positive result mean?
What does a negative result mean?
Is fasting required before the test?
Can children undergo this test?
Is genetic counseling recommended after testing?
Are there any risks associated with the test?
Related Tests
Angelman Syndrome Test
₹10,000Duchenne / Becker Muscular Dystrophy (DMD / BMD) Gene Mutation Test
₹14,000Episodic Ataxia Type 1 Hotspot Test
₹11,500Episodic Ataxia Comprehensive Profile Hotspot Test
₹16,000Megalencephalic Leukoencephalopathy with Subcortical Cysts Van Der Knaap and Nalband MLC Gene Hotspot Mutation Test
₹7,500Analyzer 18 SMA 18 Test Panel
₹1,755Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
Book Your Test
Enter your details and we'll connect you within 15 minutes.