MLC1 Gene Mutation Analysis (Agrawal Mutation) Test
Also known as: MLC1 gene test, Agrawal mutation test, MLC genetic test
MLC1 Gene Mutation Analysis (Agrawal Mutation) Test test available at DNA Labs India for ₹9,000. Uses Sanger Sequencing on Peripheral blood/Amniotic Fluid/Chorionic Villi/Cord blood samples. Results in 7-8 days. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The purpose of MLC1 Gene Mutation Analysis is to diagnose mutations in the MLC1 gene, including the Agrawal mutation, to confirm megalencephalic leukoencephalopathy with subcortical cysts (MLC). This helps in accurate diagnosis, management, and genetic counseling for individuals with symptoms or family history of the disorder.
- Test Code
- 3091
- Price
- ₹9,000
- Sample Type
- Peripheral blood/Amniotic Fluid/Chorionic Villi/Cord blood
- Result Time
- 7-8 days
- Fasting Required
- No
- Method
- Sanger Sequencing
Sample Collection
MLC1 Gene Mutation Analysis (Agrawal Mutation) can be done with a Doctor’s prescription. Prescription is not applicable for surgery and pregnancy cases or people planning to travel abroad.
Laboratory Analysis
Your sample is analyzed using Sanger Sequencing in our laboratory.
Report Delivery
A certified pathologist reviews and signs your report. You receive it as a secure PDF via email and WhatsApp.
Timeline: 7-8 days
Patient Instructions
About This Test
Who Should Get This Test
The purpose of MLC1 Gene Mutation Analysis is to diagnose mutations in the MLC1 gene, including the Agrawal mutation, to confirm megalencephalic leukoencephalopathy with subcortical cysts (MLC). This helps in accurate diagnosis, management, and genetic counseling for individuals with symptoms or family history of the disorder.
How to Prepare
- Use sterile container or EDTA Vacutainer
- Ensure proper labeling
- Transport with cool pack if needed
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"Genetic testing for MLC1 mutations is crucial for early diagnosis and management of megalencephalic leukoencephalopathy, aiding in genetic counseling and family planning."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Understanding Your Results
Positive
Pathogenic variant detected, consistent with MLC diagnosis. Consult a geneticist for management.
Negative
No pathogenic variant detected. Symptoms may be due to other causes; consider additional testing.
Consult a healthcare provider if you experience symptoms of MLC such as delayed development, seizures, or visual problems, or if you have a family history of the disorder.
Risks & Considerations
- ●Minimal physical risks from blood draw
- ●Potential psychological impact of genetic results
- ●Privacy concerns with genetic data
Frequently Asked Questions
What is MLC1 Gene Mutation Analysis?
What is the Agrawal mutation?
Who should get this test?
How is the test performed?
What is the cost of the test?
Is home sample collection available?
How long does it take to get results?
Do I need a doctor's prescription?
What are the symptoms of MLC?
Can this test be done during pregnancy?
Is the test covered by insurance?
What should I do if the test is positive?
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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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