MSTN Gene Muscle hypertrophy NGS Genetic Test
Short Name: MSTN NGS Genetic Test
Also known as: Myostatin gene NGS test, MSTN mutation analysis, Muscle hypertrophy genetic test, Myostatin-related muscle hypertrophy genetic test
MSTN Gene Muscle hypertrophy NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in Samples are processed after receipt in the laboratory. The clinical report is generally available within 3 to 4 weeks.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of this test is to detect pathogenic or likely pathogenic variants in the MSTN gene that may disrupt myostatin signalling and lead to increased muscle mass. It is intended to support a clinical diagnosis of myostatin-related muscle hypertrophy, aid genetic counselling, and provide valuable information for clinical management and family planning.
- Test Code
- 4346
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- Samples are processed after receipt in the laboratory. The clinical report is generally available within 3 to 4 weeks.
- Fasting Required
- No
- Method
- Next Generation Sequencing (NGS)
Sample Collection
No fasting is required. Please carry the doctor's prescription, previous genetic reports, and available family history details. A genetic counselling session may be requested to draw a pedigree of family members affected with MSTN gene muscle hypertrophy.
Method: Peripheral blood draw or FTA blood spot
Laboratory Analysis
A trained phlebotomist will collect a standard blood sample in an EDTA tube or a one-drop blood sample on an FTA card as instructed. The procedure is quick and minimally invasive.
Report Delivery
There are no activity restrictions after sample collection. The sample is transported to the laboratory as per the provided instructions. The report will be shared through the selected delivery option.
Timeline: Samples are processed after receipt in the laboratory. The clinical report is generally available within 3 to 4 weeks.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to detect pathogenic or likely pathogenic variants in the MSTN gene that may disrupt myostatin signalling and lead to increased muscle mass. It is intended to support a clinical diagnosis of myostatin-related muscle hypertrophy, aid genetic counselling, and provide valuable information for clinical management and family planning.
How to Prepare
- Samples can be collected at home for online bookings, free of cost in most cities.
- If an FTA card is used, allow the blood spot to air-dry completely before placing it in the provided cover.
- Label the sample with the patient's name, date of collection, and unique ID as per the requisition form.
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Pre-test genetic counselling is essential to document family history, confirm clinical indication and obtain informed consent. Post-test counselling helps families understand inheritance and reproductive implications of an MSTN gene variant."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Haemolysed or clotted blood sample
- Incorrectly labelled or unlabelled sample
- Insufficient sample quantity
- Wet or improperly handled FTA card
- Incomplete requisition form without clinical details
Understanding Your Results
No pathogenic/likely pathogenic variant detected
Pathogenic or likely pathogenic variant detected
Variant of uncertain significance (VUS) identified
Consult a clinical geneticist, neurologist, or obstetrician-gynecologist if you have unexplained muscle hypertrophy, reduced functional mobility, a family history of myostatin-related muscle hypertrophy, or if you are planning a family and are known to carry an MSTN variant.
Limitations
- ⚠This test is limited to the MSTN gene and may not detect variants in other genes associated with increased muscle mass.
- ⚠Standard NGS may not reliably detect large deletions, duplications, repeat expansions, or deep intronic variants.
- ⚠Variants of uncertain significance may require additional family studies or functional evidence for classification.
- ⚠Negative results do not entirely exclude the possibility of a genetic form of muscle hypertrophy caused by other genes.
Risks & Considerations
- ●No significant physical risks from blood collection
- ●Possible mild bruising or discomfort at the venepuncture site
- ●Psychological impact of receiving genetic test results
Interfering Factors
- ●Poor quality or degraded DNA sample
- ●Sample contamination or sample mix-up
- ●Incomplete clinical or family history
- ●Rare variants of uncertain significance that require familial segregation studies
Compare With Similar Tests
| Test | MSTN Gene Muscle hypertrophy NGS Genetic Test | |||
|---|---|---|---|---|
| Comparison | MSTN Gene Muscle hypertrophy NGS Genetic Test |
Frequently Asked Questions
What is the MSTN gene muscle hypertrophy NGS genetic test?
What does the MSTN gene do?
Who should take this test?
What is the cost of the MSTN gene muscle hypertrophy NGS genetic test at DNA Labs India?
What sample is required for this test?
Do I need to be fasting for this genetic test?
How long will my report take?
Will I receive my raw data, FASTQ, and VCF files?
What does a no pathogenic variant detected result mean?
What is a variant of uncertain significance?
Is genetic counselling recommended before and after this test?
Does home sample collection cost extra?
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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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