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MT-TM Gene Mitochondrial myopathy, MT-TM related NGS Genetic Test

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MT-TM Gene Mitochondrial myopathy, MT-TM related NGS Genetic Test

Short Name: MT-TM Gene NGS Test

Also known as: Mitochondrial Myopathy Genetic Test, MT-TM Gene Analysis, MT-TM Mutation Screening

MT-TM Gene Mitochondrial myopathy, MT-TM related NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

Next-Generation Sequencing (NGS)🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

To identify pathogenic mutations in the MT-TM gene associated with mitochondrial myopathy, enabling accurate diagnosis, personalized treatment, and genetic counseling for affected individuals and their families.

Test Code
5274
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
Next-Generation Sequencing (NGS)
Step 1

Sample Collection

No specific preparation required. Provide clinical history and family pedigree chart during genetic counseling.

Method: Venipuncture or finger-prick for FTA card

Step 2

Laboratory Analysis

Blood sample collected via venipuncture or finger-prick for FTA card by a trained phlebotomist.

Step 3

Report Delivery

Apply pressure to the puncture site. Store samples as per instructions for stability.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Undergo genetic counseling to discuss test implications and provide family history.
2
During the Test:Sample collection takes about 10-15 minutes; no pain beyond a needle prick.
3
After the Test:Resume normal activities. Await results in 3-4 weeks.

About This Test

Who Should Get This Test

To identify pathogenic mutations in the MT-TM gene associated with mitochondrial myopathy, enabling accurate diagnosis, personalized treatment, and genetic counseling for affected individuals and their families.

How to Prepare

  • Ensure proper labeling of samples
  • Use aseptic techniques
  • Transport samples at room temperature unless specified

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Early genetic testing for mitochondrial myopathy aids in symptom management and informed family planning decisions."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Sample Volume3-5 mL blood or equivalent
ContainerEDTA tube or FTA card
Collection MethodVenipuncture or finger-prick for FTA card

Sample Stability

Blood samples stable for 24 hours at room temperature
Extracted DNA stable for longer periods at -20°C
Sample Rejection Criteria:
  • Hemolyzed or clotted samples
  • Insufficient sample volume
  • Improperly labeled samples

Understanding Your Results

Results indicate the presence or absence of pathogenic variants in the MT-TM gene. Positive results confirm a genetic basis for mitochondrial myopathy, while negative results may require further testing.
Consult a geneticist for result interpretation
Correlate with clinical symptoms and family history
Consider genetic counseling for family planning
⚠️ When to Consult a Doctor:

If experiencing symptoms of mitochondrial myopathy, have a family history of the disorder, or for reproductive planning after a positive test result.

Limitations

  • ⚠May not detect all genetic variants
  • ⚠Requires interpretation by a geneticist
  • ⚠Results should be correlated with clinical findings

Risks & Considerations

  • ●Minimal risk from blood draw, such as bruising or infection
  • ●Psychological impact of genetic results

Interfering Factors

  • ●Poor sample quality
  • ●Contamination during collection
  • ●Hemolyzed blood samples

Compare With Similar Tests

TestMT-TM Gene Mitochondrial myopathy, MT-TM related NGS Genetic TestMuscle BiopsyBlood Enzyme TestsWhole Exome Sequencing
ComparisonMT-TM Gene Mitochondrial myopathy, MT-TM related NGS Genetic Test

Frequently Asked Questions

What is MT-TM gene mitochondrial myopathy?
It is a rare genetic disorder caused by mutations in the MT-TM gene, affecting mitochondrial function and leading to muscle weakness and other symptoms.
What are the common symptoms?
Symptoms include muscle weakness, fatigue, exercise intolerance, difficulty swallowing, vision and hearing problems, and developmental delays in children.
How is it diagnosed?
Diagnosis involves muscle biopsy, blood tests, and genetic testing such as NGS to identify MT-TM gene mutations.
What is NGS genetic testing?
Next-generation sequencing (NGS) is an advanced method that analyzes multiple genes simultaneously for comprehensive genetic diagnosis.
What is the cost of the test in India?
The NGS Genetic Test for MT-TM gene mitochondrial myopathy costs INR 20,000 at DNA Labs India.
Is home sample collection available?
Yes, free home sample collection is available for online bookings across India.
How long does it take to get results?
Results are typically available in 3 to 4 weeks after sample collection.
Is the test covered by insurance?
Coverage depends on your insurance policy; check with your provider for details.
What should I do before the test?
Undergo genetic counseling to provide clinical history and understand test implications.
How is the sample collected?
A blood sample is collected via venipuncture or a finger-prick for FTA card by a trained professional.
What do the results mean?
Results indicate the presence or absence of pathogenic variants in the MT-TM gene; consult a geneticist for interpretation.
Who should get tested?
Individuals with symptoms of mitochondrial myopathy, a family history of the disorder, or for reproductive planning.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

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Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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