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MT-TV Gene Ataxia, Progressive Seizures, Mental Deterioration, and Hearing Loss, MT-TV Related NGS Genetic Test

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MT-TV Gene Ataxia, Progressive Seizures, Mental Deterioration, and Hearing Loss, MT-TV Related NGS Genetic Test

Short Name: MT-TV NGS Genetic Test

Also known as: Mitochondrial MT-TV gene disorder, MT-TV related mitochondrial ataxia, MT-TV mutation test

MT-TV Gene Ataxia, Progressive Seizures, Mental Deterioration, and Hearing Loss, MT-TV Related NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

To identify mutations in the MT-TV gene associated with ataxia, progressive seizures, mental deterioration, and hearing loss for diagnostic confirmation and family planning.

Test Code
1515
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
Next-Generation Sequencing (NGS)
Step 1

Sample Collection

Clinical history and genetic counseling session recommended. No fasting required.

Method: Venipuncture or Spot Collection

Step 2

Laboratory Analysis

Blood sample collected via venipuncture or FTA card spot collection.

Step 3

Report Delivery

Sample labeled and sent to laboratory for processing.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Genetic counseling to assess family history and draw a pedigree chart. Provide clinical history of the patient.
2
During the Test:Sample collection and processing in the laboratory using NGS technology.
3
After the Test:Report generation, interpretation by geneticist, and counseling session to discuss results.

About This Test

Who Should Get This Test

To identify mutations in the MT-TV gene associated with ataxia, progressive seizures, mental deterioration, and hearing loss for diagnostic confirmation and family planning.

How to Prepare

  • Ensure proper sample labeling
  • Avoid contamination
  • Use sterile collection materials

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Genetic testing for MT-TV gene mutations is crucial for confirming diagnosis and informing treatment strategies for mitochondrial ataxia syndromes."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
ContainerEDTA tube or FTA Card
Collection MethodVenipuncture or Spot Collection

Sample Stability

Blood samples stable for 48 hours at room temperature
Sample Rejection Criteria:
  • Insufficient sample volume
  • Contaminated or hemolyzed sample
  • Incorrect sample type

Understanding Your Results

Results indicate the presence or absence of pathogenic mutations in the MT-TV gene.
Positive result: Pathogenic variant detected, suggesting diagnosis of MT-TV gene ataxia. Clinical correlation and genetic counseling recommended.
Negative result: No pathogenic variant detected. Consider other genetic or non-genetic causes. Further testing may be needed.
Variant of uncertain significance: May require additional family studies or functional analysis.
⚠️ When to Consult a Doctor:

If symptoms such as ataxia, progressive seizures, mental deterioration, or hearing loss are present, consult a neurologist or geneticist for evaluation and consideration of genetic testing.

Limitations

  • ⚠May not detect all genetic variants
  • ⚠Requires clinical correlation and genetic counseling for interpretation

Risks & Considerations

  • ●Minimal risk of bruising, bleeding, or infection at the blood draw site

Interfering Factors

  • ●Hemolyzed samples
  • ●Contaminated DNA

Frequently Asked Questions

What is MT-TV Gene Ataxia?
MT-TV Gene Ataxia is a rare genetic disorder caused by mutations in the MT-TV gene, leading to progressive neurological symptoms such as ataxia, seizures, mental deterioration, and hearing loss.
What are the symptoms of MT-TV Gene Ataxia?
Symptoms include loss of coordination (ataxia), progressive seizures, mental decline, hearing loss, visual impairment, dementia, and muscle weakness, often starting in childhood or early adulthood.
How is MT-TV Gene Ataxia diagnosed?
Diagnosis is confirmed through genetic testing, specifically the MT-TV NGS Genetic Test, which analyzes blood or DNA samples for mutations in the MT-TV gene.
What is the cost of the MT-TV NGS Genetic Test?
The test costs INR 20000, inclusive of home sample collection across India.
What sample is required for the test?
The test requires a blood sample, extracted DNA, or one drop of blood on an FTA card.
How long does it take to get the test results?
Results are typically available within 3 to 4 weeks after sample collection.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection for online bookings across numerous cities in India.
Do I need to fast before the test?
No, fasting is not required for this genetic test.
What does a positive test result mean?
A positive result indicates the presence of a pathogenic MT-TV gene mutation, confirming the diagnosis. Genetic counseling is recommended for management and family planning.
What if the test result is negative?
A negative result means no pathogenic variant was detected. Clinical correlation with symptoms is essential, and other genetic or non-genetic causes should be explored.
Is genetic counseling provided with the test?
Yes, a genetic counseling session is recommended and included to discuss results, implications, and family pedigree analysis.
How can I book this test?
You can book the test online via DNA Labs India's website or contact them via phone or WhatsApp for sample collection arrangements.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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