N. Gonorrhoea (RNA Detection) Qualitative Test
Short Name: N. Gonorrhoea RNA Qualitative
Also known as: Gonorrhea RNA Test, Neisseria gonorrhoeae RNA PCR, GC RNA Detection
N. Gonorrhoea (RNA Detection) Qualitative Test test available at DNA Labs India for ₹5,780. Uses Real-Time PCR, RNA Amplification on Urine, Urethral swab, Vaginal swab, Cervical swab, Rectal swab, Pharyngeal swab samples. Results in Reports are available on the 4th working day after sample collection. Email reports within 48 hours of result release, phone within 36 hours.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Kothari Ramesh Shantilal
Consultant Microbiologist · Reg: 27670
Last reviewed: September 7, 2026
Overview
The primary purpose of this test is to diagnose active Neisseria gonorrhoeae infection. It is used for symptomatic individuals with discharge, dysuria, or genital discomfort, as well as for screening high-risk populations, including sexually active individuals under 25, men who have sex with men, and those with multiple partners. The test also aids in confirming infection in cases where culture is difficult or negative, and it can be used for test-of-cure after treatment, although guidelines recommend waiting at least 2 weeks post-therapy. Additionally, it helps in preventing the spread of infection by identifying asymptomatic carriers who might otherwise unknowingly transmit the disease.
- Test Code
- 6217
- CPT Code
- 87591
- ICD Code
- A54.9
- Price
- ₹5,780
- Sample Type
- Urine, Urethral swab, Vaginal swab, Cervical swab, Rectal swab, Pharyngeal swab
- Result Time
- Reports are available on the 4th working day after sample collection. Email reports within 48 hours of result release, phone within 36 hours.
- Fasting Required
- No
- Method
- Real-Time PCR, RNA Amplification
Sample Collection
No fasting required. Avoid urinating for at least 1 hour before urine sample collection. For swab samples, avoid using antibacterial soaps or douches 24 hours prior. Inform your healthcare provider about any antibiotics taken in the last 3 weeks.
Method: Healthcare professional collection or self-collection (for vaginal swab) with guidance
Laboratory Analysis
For urine sample, collect first-void urine (initial stream) in a sterile container. For swabs, a healthcare professional will collect a sample from the urethra, cervix, rectum, or throat using a sterile swab. The procedure may cause mild discomfort but is generally quick.
Report Delivery
No special precautions. You may resume normal activities immediately. Results will be available within 4 working days. If symptoms persist, contact your physician.
Timeline: Reports are available on the 4th working day after sample collection. Email reports within 48 hours of result release, phone within 36 hours.
Patient Instructions
About This Test
Who Should Get This Test
The primary purpose of this test is to diagnose active Neisseria gonorrhoeae infection. It is used for symptomatic individuals with discharge, dysuria, or genital discomfort, as well as for screening high-risk populations, including sexually active individuals under 25, men who have sex with men, and those with multiple partners. The test also aids in confirming infection in cases where culture is difficult or negative, and it can be used for test-of-cure after treatment, although guidelines recommend waiting at least 2 weeks post-therapy. Additionally, it helps in preventing the spread of infection by identifying asymptomatic carriers who might otherwise unknowingly transmit the disease.
How to Prepare
- Urine: Collect first-void urine (first 20-30 ml) in a sterile cup. Do not wipe or clean the genital area before collection.
- Urethral swab: Insert swab 2-4 cm into urethra and rotate for 10 seconds.
- Vaginal swab: Use a speculum to collect from posterior fornix or use a self-collection kit as instructed.
- Rectal swab: Insert swab 3 cm into rectum and rotate for 10 seconds.
- Pharyngeal swab: Swab the posterior pharynx and tonsils.
- All samples should be transported to the lab immediately or stored at 2-8°C for up to 24 hours.
Doctor's Notes
Reviewed by Dr Kothari Ramesh Shantilal — MBBS, MD (Microbiology) · Reg. No. 27670
"Early detection of N. gonorrhoeae is crucial to prevent complications such as pelvic inflammatory disease and infertility. This RNA-based test offers high sensitivity, enabling prompt treatment."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Sample received in inappropriate container
- Sample with visible contamination or excessive blood
- Sample not labeled correctly
- Sample stored at room temperature for more than 24 hours
- Insufficient volume
Understanding Your Results
Positive
Neisseria gonorrhoeae RNA detected. Active gonorrhea infection. Treatment with appropriate antibiotics is required. Partner notification and testing are recommended.
Clinical action: Start antibiotic therapy as per local guidelines. Advise patient to abstain from sexual activity until treatment completed. Offer testing for other STIs including HIV, syphilis, and chlamydia.
Negative
No Neisseria gonorrhoeae RNA detected. No evidence of current infection.
Clinical action: If symptoms persist, consider alternative diagnoses or repeat testing after 2 weeks. Continue routine STI screening as recommended.
Consult a physician immediately if you experience symptoms such as burning during urination, unusual discharge, pelvic pain, or if you have had unprotected sexual contact with a partner diagnosed with gonorrhea. Early treatment prevents complications.
Limitations
- ⚠This test detects RNA, not viable organisms; it cannot differentiate between live and dead bacteria
- ⚠Positive results do not indicate antibiotic susceptibility; culture may be needed for resistance testing
- ⚠False negatives possible if sample is collected too early after exposure (incubation period 2-7 days)
- ⚠Not recommended for medico-legal cases without additional confirmation
Risks & Considerations
- ●Minimal risk of discomfort during swab collection
- ●Rarely, minor bleeding or infection at the collection site
- ●No significant systemic risks
Interfering Factors
- ●Recent antibiotic use (within 3 weeks) may reduce bacterial load and cause false negatives
- ●Contamination of sample with urine or lubricants can inhibit PCR
- ●Improper sample collection or storage may degrade RNA
- ●Presence of inhibitors in the sample (e.g., blood, mucus) can affect amplification
Compare With Similar Tests
| Test | N. Gonorrhoea (RNA Detection) Qualitative Test | Gram Stain | Culture | NAAT (DNA-based) |
|---|---|---|---|---|
| Comparison | N. Gonorrhoea (RNA Detection) Qualitative Test |
Frequently Asked Questions
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