NCF2 Gene Granulomatous disease, chronic, autosomal recessive, cytochrome b-positive, type 2 NGS Genetic Test
Short Name: NCF2 Gene CGD2 NGS Test
Also known as: Chronic Granulomatous Disease Type 2 Genetic Test, NCF2 Mutation Analysis, CGD2 NGS Test
NCF2 Gene Granulomatous disease, chronic, autosomal recessive, cytochrome b-positive, type 2 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 3, 2026
Overview
The purpose of the NCF2 Gene NGS Genetic Test is to identify mutations in the NCF2 gene that cause Chronic Granulomatous Disease Type 2 (CGD2). This test aids in accurate diagnosis, guides treatment strategies, and supports genetic counseling for affected individuals and their families.
- Test Code
- 4949
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 Weeks
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
No specific preparation required, but provide clinical history and family pedigree information.
Laboratory Analysis
Blood sample collected via venipuncture or using FTA card for one drop of blood.
Report Delivery
Sample sent to laboratory for NGS analysis; results available in 3 to 4 weeks.
Timeline: 3 to 4 Weeks
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the NCF2 Gene NGS Genetic Test is to identify mutations in the NCF2 gene that cause Chronic Granulomatous Disease Type 2 (CGD2). This test aids in accurate diagnosis, guides treatment strategies, and supports genetic counseling for affected individuals and their families.
How to Prepare
- Ensure proper labeling of sample
- Use sterile collection tubes
- Transport sample at ambient room temperature
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Early genetic testing for CGD2 can guide treatment and family planning, especially for families with a history of immunodeficiency."
Last medically reviewed: September 3, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted blood sample
- Insufficient sample volume
- Improperly labeled or contaminated samples
Understanding Your Results
No pathogenic variants detected
Normal result; low likelihood of CGD2 due to NCF2 mutations
Pathogenic variant detected
Confirms diagnosis of CGD2; genetic counseling recommended
Variant of uncertain significance (VUS)
Further testing or family studies may be needed for clarification
Consult a doctor if you experience recurrent infections, chronic inflammation, or have a family history of CGD2. After testing, consult for result interpretation and management plans.
Limitations
- ⚠May not detect all types of mutations, such as large deletions or intronic variants
- ⚠Requires genetic counseling for proper interpretation
- ⚠Results should be correlated with clinical findings
Risks & Considerations
- ●Minimal risks from blood draw, such as bruising or infection
- ●Psychological impact of genetic results; counseling available
Interfering Factors
- ●Sample contamination or degradation
- ●Insufficient DNA quantity or quality
- ●Recent blood transfusions affecting DNA analysis
Compare With Similar Tests
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|---|---|---|---|---|
| Comparison | NCF2 Gene Granulomatous disease, chronic, autosomal recessive, cytochrome b-positive, type 2 NGS Genetic Test |
Frequently Asked Questions
What is NCF2 Gene Granulomatous Disease?
What are the common symptoms of CGD2?
How is CGD2 diagnosed?
What is the cost of the NCF2 Gene NGS Genetic Test?
Is home sample collection available for this test?
How long does it take to receive the test results?
What does a positive test result mean?
Can CGD2 be treated?
Is the test covered by insurance?
Who should consider this genetic test?
What is the accuracy of NGS testing for CGD2?
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