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DNA Labs India

NCL Enzyme Panel NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

NCL Enzyme Panel NGS Genetic Test

Short Name: NCL Enzyme Panel

Also known as: Neuronal Ceroid Lipofuscinosis Enzyme Panel, NCL Genetic Test

NCL Enzyme Panel NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS (Next Generation Sequencing) on Blood, Extracted DNA, or Blood on FTA Card samples. Results in 3-4 weeks. Free home collection in 300+ cities across India.

Genetic🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

The purpose of the NCL Enzyme Panel NGS Genetic Test is to diagnose genetic mutations in NCL enzymes that cause neurodegenerative disorders, enabling early detection, family planning, and informed medical management.

Test Code
1858
Price
₹20,000
Sample Type
Blood, Extracted DNA, or Blood on FTA Card
Result Time
3-4 weeks
Fasting Required
No
Method
NGS (Next Generation Sequencing)
Step 1

Sample Collection

No special preparation is required. Bring identification documents and any relevant medical history.

Method: Venipuncture or Saliva

Step 2

Laboratory Analysis

A trained professional will collect a blood sample via venipuncture or a saliva sample in a non-invasive manner.

Step 3

Report Delivery

Apply pressure to the puncture site if blood is drawn. Resume normal activities immediately.

Timeline: 3-4 weeks

Patient Instructions

1
Before the Test:No special preparation required. Genetic counseling session is recommended to draw a family pedigree chart.
2
During the Test:Sample collection is quick and non-invasive, taking approximately 15-30 minutes.
3
After the Test:Results are analyzed in the laboratory, and reports are delivered within 3-4 weeks via online portal, email, or WhatsApp.

About This Test

Who Should Get This Test

The purpose of the NCL Enzyme Panel NGS Genetic Test is to diagnose genetic mutations in NCL enzymes that cause neurodegenerative disorders, enabling early detection, family planning, and informed medical management.

How to Prepare

  • Fasting is not required
  • Avoid eating or drinking 30 minutes before saliva collection
  • Bring referral form if available

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"As a physician, I recommend this test for individuals with a family history of neurodegenerative disorders or those planning pregnancy to assess carrier status and guide diagnosis."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood, Extracted DNA, or Blood on FTA Card
Collection MethodVenipuncture or Saliva

Sample Stability

Blood sample stable for 48 hours at room temperature
Saliva sample stable for 5 days at 4°C
Sample Rejection Criteria:
  • Hemolyzed or clotted blood sample
  • Insufficient sample volume
  • Contaminated sample

Understanding Your Results

Results indicate the presence or absence of pathogenic mutations in NCL-related genes. Positive results may confirm a diagnosis, while negative results suggest no detectable mutations, but clinical correlation is advised.
📊

Negative

No pathogenic variants detected in NCL genes. Does not completely rule out other genetic causes.

📊

Positive

Pathogenic variant(s) identified, indicating genetic basis for neurodegenerative disorder. Genetic counseling recommended.

📊

Variant of Uncertain Significance (VUS)

Genetic variant found with unclear clinical significance. Further testing and monitoring may be needed.

⚠️ When to Consult a Doctor:

If symptoms of neurodegenerative disorders persist or worsen, or if you have a family history and are planning pregnancy. Consult a genetic counselor or neurologist for result interpretation.

Limitations

  • ⚠May not detect all genetic variants
  • ⚠Requires genetic counseling for interpretation
  • ⚠Results may have limitations in ethnically diverse populations

Risks & Considerations

  • ●Minor bruising or discomfort at puncture site
  • ●Very low risk of infection
  • ●Minimal pain during blood draw

Interfering Factors

  • ●Poor sample quality
  • ●DNA contamination
  • ●Improper sample storage

Frequently Asked Questions

What is the NCL Enzyme Panel NGS Genetic Test?
It is a genetic test that analyzes DNA sequences of NCL enzymes to identify mutations causing neurodegenerative disorders using Next Generation Sequencing (NGS) technology.
What symptoms indicate the need for this test?
Symptoms such as memory loss, muscle weakness, tremors, difficulty moving, loss of coordination, speech problems, vision problems, behavioral changes, and personality changes may warrant testing.
How is the test performed?
A small sample of blood or saliva is collected non-invasively and sent to the laboratory for NGS analysis.
What is the cost of the NCL Enzyme Panel NGS Genetic Test?
The cost at DNA Labs India is INR 20000, including sample collection, analysis, and interpretation. Free home sample collection is available for online bookings.
Who should undergo this test?
Individuals with a family history of neurodegenerative disorders, those experiencing symptoms, or those planning children to assess carrier status should consider this test.
How long does it take to get results?
Results are typically available within 3-4 weeks after sample collection.
Is the test safe and non-invasive?
Yes, the test involves a simple blood or saliva draw, which is safe and non-invasive with minimal risks.
What does a positive result mean?
A positive result indicates the presence of pathogenic mutations in NCL genes, suggesting a genetic basis for a neurodegenerative disorder. Genetic counseling is recommended.
Can this test be used for prenatal diagnosis?
This test is primarily for postnatal diagnosis. For prenatal testing, consult a genetic counselor for appropriate options.
Is genetic counseling required before the test?
Yes, a genetic counseling session is recommended to understand the test implications, draw a family pedigree chart, and interpret results.
Does DNA Labs India offer home sample collection?
Yes, free home sample collection is available for online bookings across many cities in India. Check availability during booking.
What should I do before getting tested?
Before testing, provide clinical history, undergo genetic counseling, and request raw data, FASTQ, and VCF files along with the clinical report for transparency.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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