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OCLN Gene Band-like calcification with simplified gyration and polymicrogyria NGS Genetic Test

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OCLN Gene Band-like calcification with simplified gyration and polymicrogyria NGS Genetic Test

Short Name: OCLN Gene BLC-SG-PMG NGS Test

Also known as: OCLN Gene Disorder, Band-like Calcification with Simplified Gyration and Polymicrogyria, OCLN-related Brain Disorder

OCLN Gene Band-like calcification with simplified gyration and polymicrogyria NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.

NGS Genetic TestPediatric🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

The purpose of this test is to diagnose band-like calcification with simplified gyration and polymicrogyria by detecting mutations in the OCLN gene, enabling early treatment, genetic counseling, and family planning.

Test Code
5662
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 weeks
Fasting Required
No
Method
Next-Generation Sequencing (NGS)
Step 1

Sample Collection

Provide clinical history and undergo genetic counseling to draw a pedigree chart.

Method: Venipuncture or Blood Drop

Step 2

Laboratory Analysis

Blood sample collected via venipuncture or blood drop on FTA card.

Step 3

Report Delivery

Sample sent to lab for analysis; results available in 3-4 weeks.

Timeline: 3 to 4 weeks

Patient Instructions

1
Before the Test:Genetic counseling and clinical history review are recommended before testing.
2
During the Test:Blood sample collection; analysis performed using NGS technology.
3
After the Test:Results discussed with genetic counselor; follow-up care as needed.

About This Test

Who Should Get This Test

The purpose of this test is to diagnose band-like calcification with simplified gyration and polymicrogyria by detecting mutations in the OCLN gene, enabling early treatment, genetic counseling, and family planning.

How to Prepare

  • Fast not required
  • Bring identification and prescription
  • Ensure proper sample labeling

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"This test is crucial for early diagnosis and management of OCLN-related disorders, aiding in genetic counseling and family planning."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Sample VolumeAs required
ContainerEDTA tube or FTA Card
Collection MethodVenipuncture or Blood Drop

Sample Stability

Blood: Store at 2-8°C for up to 24 hours
FTA Card: Room temperature stable
Sample Rejection Criteria:
  • Insufficient sample volume
  • Hemolyzed or clotted blood
  • Incorrect sample type

Understanding Your Results

Results indicate the presence or absence of pathogenic variants in the OCLN gene. Positive results confirm diagnosis, while negative results may require further testing.
📊

Positive for pathogenic variant

Confirms diagnosis of band-like calcification with simplified gyration and polymicrogyria; genetic counseling recommended.

📊

Negative for pathogenic variant

No mutations detected; clinical correlation and additional tests may be needed.

📊

Variant of uncertain significance

Further evaluation and family studies required.

⚠️ When to Consult a Doctor:

Consult a healthcare provider if symptoms like seizures, developmental delays, or microcephaly are present, or for genetic counseling after test results.

Limitations

  • ⚠May not detect all genetic variants
  • ⚠Requires genetic counseling for interpretation
  • ⚠Results may need confirmation with additional tests

Risks & Considerations

  • ●Minimal risk from blood draw, such as bruising or infection

Interfering Factors

  • ●Sample contamination
  • ●Degraded DNA
  • ●Incorrect sample storage

Compare With Similar Tests

TestOCLN Gene Band-like calcification with simplified gyration and polymicrogyria NGS Genetic TestWhole Exome SequencingChromosomal MicroarrayMRI BrainEEG
ComparisonOCLN Gene Band-like calcification with simplified gyration and polymicrogyria NGS Genetic TestBroader genetic analysis but higher cost; OCLN test is targeted.Detects chromosomal abnormalities; OCLN test focuses on single gene mutations.Imaging test for structural abnormalities; OCLN test is genetic.Measures electrical activity for seizures; OCLN test identifies genetic cause.

Frequently Asked Questions

What is the OCLN Gene BLC-SG-PMG NGS Genetic Test?
It is a genetic test that analyzes the OCLN gene for mutations causing band-like calcification with simplified gyration and polymicrogyria, a rare brain development disorder.
What are the symptoms of this disorder?
Symptoms include intellectual disability, seizures, developmental delays, microcephaly, weak muscle tone, and feeding difficulties.
How is the test performed?
A blood sample or DNA is collected and analyzed using Next-Generation Sequencing technology to detect OCLN gene mutations.
What is the cost of the test?
The test costs INR 20000, with home sample collection available across India.
Is the test covered by insurance?
Yes, it is covered by most major insurance plans. Check with your provider for specifics.
How long does it take to get results?
Results are typically available in 3 to 4 weeks.
Is fasting required before the test?
No, fasting is not required for this test.
Can the test be done at home?
Yes, DNA Labs India offers free home sample collection for online bookings.
What if the test result is positive?
A positive result confirms the diagnosis, and genetic counseling is recommended for management and family planning.
What if the test result is negative?
A negative result means no mutations were detected, but clinical correlation and additional tests may be needed.
Who should take this test?
It is recommended for individuals, especially children, with symptoms of the disorder or a family history of similar conditions.
Is genetic counseling included?
Yes, a genetic counseling session is included to draw a pedigree chart and discuss results.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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