Parietal Cell Antibody IFA in Dilutions Test
Short Name: PCA IFA Dilutions
Also known as: Parietal Cell Antibodies, PCA Test, Gastric Parietal Cell Antibody IFA
Parietal Cell Antibody IFA in Dilutions Test test available at DNA Labs India for ₹4,500. Uses Indirect Immunofluorescence Assay (IFA) on Serum samples. Results in Reports are delivered within 24-36 hours after sample collection.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SHAILAJA RAGHUNATH MURDESHWAR
Consultant Physician · Reg: 8052
Last reviewed: September 7, 2026
Overview
The primary purpose of this test is to assist in the diagnosis of pernicious anemia and autoimmune gastritis by detecting parietal cell antibodies in the blood. It helps clinicians evaluate the cause of vitamin B12 deficiency and distinguish between pernicious anemia and other types of anemia.
- Test Code
- 3525
- Price
- ₹4,500
- Sample Type
- Serum
- Result Time
- Reports are delivered within 24-36 hours after sample collection.
- Fasting Required
- No
- Method
- Indirect Immunofluorescence Assay (IFA)
Sample Collection
Overnight fasting is preferred but not mandatory. Inform your healthcare provider about all medications and supplements you are currently taking, particularly vitamin B12 injections or oral supplements, as they may affect results.
Method: Venipuncture
Laboratory Analysis
A blood sample will be drawn from a vein in your arm. Some discomfort is possible but usually brief.
Report Delivery
You may resume normal activities immediately after the sample collection. Apply pressure to the puncture site to minimize bruising.
Timeline: Reports are delivered within 24-36 hours after sample collection.
Patient Instructions
About This Test
Who Should Get This Test
The primary purpose of this test is to assist in the diagnosis of pernicious anemia and autoimmune gastritis by detecting parietal cell antibodies in the blood. It helps clinicians evaluate the cause of vitamin B12 deficiency and distinguish between pernicious anemia and other types of anemia.
How to Prepare
- Overnight fasting is preferred but not mandatory.
- Inform your doctor about any medications, especially vitamin B12 supplements.
- Do not stop any prescription medicine without consulting your doctor.
Doctor's Notes
Reviewed by Dr SHAILAJA RAGHUNATH MURDESHWAR — MBBS, MD (General Medicine) · Reg. No. 8052
"Parietal cell antibodies are found in 80-90% of patients with pernicious anemia, but also in up to 10% of healthy adults. Clinical correlation is essential."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Grossly hemolyzed sample
- Improperly labeled sample
- Sample received in wrong container
- Clotted sample (if serum required)
Understanding Your Results
Negative
No antibodies detected; suggests low likelihood of autoimmune gastritis, but clinical correlation is still necessary.
Positive
Indicates the presence of parietal cell antibodies, supporting a diagnosis of autoimmune gastritis or pernicious anemia when correlated with symptoms and other tests such as vitamin B12 levels.
If you have symptoms such as persistent fatigue, weakness, pale skin, or neurological changes, consult your healthcare provider. Your doctor may order this test to evaluate for pernicious anemia.
Limitations
- ⚠A negative test does not completely rule out pernicious anemia, as antibody levels may decline with disease progression or after treatment.
- ⚠Positive results can occur in healthy individuals, especially older adults, without clinically apparent disease.
- ⚠The test alone is not sufficient for a diagnosis and must be used alongside other laboratory tests.
Risks & Considerations
- ●Mild discomfort at the puncture site
- ●Bruising
- ●Infection (rare)
Interfering Factors
- ●Recent administration of radioactive isotopes or contrast media
- ●Haemolysis or lipemia of sample
- ●Interference from rheumatoid factors or other autoantibodies
- ●Concomitant treatment with immunosuppressive drugs
Compare With Similar Tests
| Test | Parietal Cell Antibody IFA in Dilutions Test | Intrinsic Factor Antibody Test | Serum Gastrin Level |
|---|---|---|---|
| Comparison | Parietal Cell Antibody IFA in Dilutions Test |
Frequently Asked Questions
What is the Parietal Cell Antibody IFA in Dilutions Test?
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