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PDE8B Gene Striatal degeneration NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

PDE8B Gene Striatal degeneration NGS Genetic Test

Short Name: PDE8B Striatal Degeneration NGS Test

Also known as: PDE8B Gene Mutation Test, Striatal Degeneration Genetic Test, PDE8B NGS Test

PDE8B Gene Striatal degeneration NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

To identify mutations in the PDE8B gene that cause striatal degeneration, aiding in diagnosis, treatment planning, and genetic counseling.

Test Code
4586
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 weeks
Fasting Required
No
Method
Next-Generation Sequencing (NGS)
Step 1

Sample Collection

No specific preparation required. Provide clinical history and family pedigree.

Method: Venipuncture for blood; FTA card for one drop blood

Step 2

Laboratory Analysis

Blood sample collected via venipuncture or one drop on FTA card.

Step 3

Report Delivery

Apply pressure to the puncture site to stop bleeding.

Timeline: 3 to 4 weeks

Patient Instructions

1
Before the Test:Provide clinical history and undergo genetic counseling.
2
During the Test:Sample collection as per instructions.
3
After the Test:Wait for report and discuss results with healthcare provider.

About This Test

Who Should Get This Test

To identify mutations in the PDE8B gene that cause striatal degeneration, aiding in diagnosis, treatment planning, and genetic counseling.

How to Prepare

  • Ensure proper identification of patient
  • Use sterile equipment
  • Label samples correctly
  • Transport samples at ambient temperature

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Genetic testing for PDE8B mutations is essential for accurate diagnosis of striatal degeneration, enabling personalized treatment strategies and informed family planning decisions."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Collection MethodVenipuncture for blood; FTA card for one drop blood

Sample Stability

Blood samples stable for 48 hours at room temperature
FTA card samples stable for extended periods
Sample Rejection Criteria:
  • Hemolyzed samples
  • Insufficient sample volume
  • Incorrect labeling

Understanding Your Results

Results indicate the presence or absence of pathogenic mutations in the PDE8B gene.
📊

Normal

No pathogenic variants detected. Symptoms may be due to other causes.

📊

Abnormal

Pathogenic variant(s) detected. Confirms diagnosis of PDE8B-related striatal degeneration.

⚠️ When to Consult a Doctor:

If symptoms persist or worsen, or if genetic testing reveals mutations, consult a neurologist or geneticist for management.

Limitations

  • ⚠May not detect all types of mutations
  • ⚠Requires genetic counseling for interpretation
  • ⚠Results should be correlated with clinical findings

Risks & Considerations

  • ●Minor bruising at puncture site
  • ●Rare infection risk

Interfering Factors

  • ●Sample contamination
  • ●Degraded DNA
  • ●Incorrect sample type

Frequently Asked Questions

What is the PDE8B Gene Striatal Degeneration NGS Genetic Test?
It is a genetic test that uses Next-Generation Sequencing to detect mutations in the PDE8B gene, which causes striatal degeneration, a rare neurological disorder.
Who should consider taking this test?
Individuals with symptoms such as movement difficulties, tremors, speech problems, or a family history of striatal degeneration should consider this test.
What are the symptoms of striatal degeneration?
Symptoms include difficulty with movement and coordination, tremors, speech and swallowing difficulties, behavioral changes, and cognitive decline.
How is the test performed?
A blood sample or DNA is collected and analyzed using NGS technology to identify mutations in the PDE8B gene.
What is the cost of the test?
The test costs INR 20,000 at DNA Labs India, with free home sample collection available.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection for this test across many cities in India.
How long does it take to get the results?
Results are typically available within 3 to 4 weeks after sample collection.
What do the test results mean?
Results indicate whether pathogenic mutations in the PDE8B gene are detected. A positive result confirms the diagnosis, while a negative result may require further investigation.
Is genetic counseling provided with the test?
Yes, DNA Labs India includes a genetic counseling session to help interpret results and discuss implications.
Can this test be used for family planning?
Yes, identifying PDE8B mutations can inform family planning decisions and genetic risks for offspring.
What are the risks associated with the test?
The test involves minimal risks, such as minor bruising from blood draw. There are no significant health risks.
How accurate is the NGS genetic test?
NGS is a highly accurate method for detecting genetic mutations, but results should be interpreted in conjunction with clinical findings and genetic counseling.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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