Peripheral Blood for Karyotyping (Couple) Test
Also known as: Peripheral Blood Karyotyping, Couple Karyotyping
Peripheral Blood for Karyotyping (Couple) Test test available at DNA Labs India for ₹7,600. Uses Cell Culture on Peripheral blood samples. Results in 10-12 days. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of peripheral blood karyotyping for couples is to identify chromosomal abnormalities that may cause genetic disorders, recurrent miscarriages, or infertility. It helps in assessing the risk of transmitting conditions to offspring and guides decisions on reproductive options, such as natural conception, IVF with genetic testing, or adoption.
- Test Code
- 3145
- Price
- ₹7,600
- Sample Type
- Peripheral blood
- Result Time
- 10-12 days
- Fasting Required
- No
- Method
- Cell Culture
Sample Collection
Ensure a doctor's prescription is available if required. Avoid strenuous activity before sample collection. Inform the healthcare provider of any medications or health conditions.
Method: Venipuncture
Laboratory Analysis
A blood sample is drawn from a vein in the arm using a sterile needle and collected in a sodium heparin vacutainer. The procedure takes about 5-10 minutes.
Report Delivery
Apply pressure to the puncture site to prevent bleeding. Keep the area clean. Resume normal activities unless advised otherwise.
Timeline: 10-12 days
Patient Instructions
About This Test
Who Should Get This Test
The purpose of peripheral blood karyotyping for couples is to identify chromosomal abnormalities that may cause genetic disorders, recurrent miscarriages, or infertility. It helps in assessing the risk of transmitting conditions to offspring and guides decisions on reproductive options, such as natural conception, IVF with genetic testing, or adoption.
How to Prepare
- Peripheral blood for karyotyping (COUPLE) can be done with a Doctor’s prescription. Prescription is not applicable for surgery and pregnancy cases or people planning to travel abroad.
- Home sample collection is available for online bookings.
- Ensure the sample is labeled correctly and transported at ambient temperature.
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"This test is crucial for couples with a history of genetic disorders, recurrent miscarriages, or planning pregnancy to assess chromosomal abnormalities and guide reproductive decisions."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted samples
- Incorrect sample type or container
- Insufficient volume
- Sample contamination or mislabeling
Understanding Your Results
Normal Karyotype (46,XX or 46,XY)
No chromosomal abnormalities detected. Low risk for related genetic disorders.
Aneuploidy (e.g., 47,XX+21)
Presence of extra or missing chromosomes, indicating conditions like Down syndrome.
Structural Abnormality (e.g., translocation)
Altered chromosome structure, which may be balanced or unbalanced, affecting genetic health.
Mosaicism
Presence of two or more cell lines with different karyotypes, requiring further evaluation.
Consult a doctor or genetic counselor if results show abnormalities, if there is a family history of genetic disorders, or if planning pregnancy after abnormal findings.
Limitations
- ⚠May not detect small genetic mutations or single-gene disorders
- ⚠Limited to numerical and large structural abnormalities
- ⚠Requires viable cells for culture, which can be affected by sample quality
Risks & Considerations
- ●Minor bruising or pain at the puncture site
- ●Rare risk of infection
- ●Fainting or dizziness in some individuals
Interfering Factors
- ●Sample contamination
- ●Improper blood collection or storage
- ●Cell culture failure
- ●Presence of maternal cell contamination in prenatal samples
Compare With Similar Tests
| Test | Peripheral Blood for Karyotyping (Couple) | Chromosomal Microarray Analysis | FISH (Fluorescent In Situ Hybridization) | Next-Generation Sequencing (NGS) | Amniocentesis |
|---|---|---|---|---|---|
| Comparison | Peripheral Blood for Karyotyping (Couple) |
Frequently Asked Questions
What is peripheral blood karyotyping?
Why is karyotyping recommended for couples?
How is the sample collected for this test?
Is fasting required for peripheral blood karyotyping?
What is the cost of karyotyping for couples at DNA Labs India?
How long does it take to get the results?
Are there any risks associated with this test?
Can karyotyping detect all genetic disorders?
What should I do if the results are abnormal?
Is home sample collection available for this test?
Do I need a doctor's prescription for this test?
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