PICALM Gene Immunological disorder, PICALM related NGS Genetic Test
Short Name: PICALM NGS Genetic Test
Also known as: PICALM Mutation Test, PICALM Gene Sequencing
PICALM Gene Immunological disorder, PICALM related NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of the PICALM Gene NGS Genetic Test is to identify pathogenic mutations in the PICALM gene that may cause or predispose individuals to immunological disorders such as Alzheimer's disease and leukemia. This test aids healthcare providers in making accurate diagnoses, guiding treatment decisions, and facilitating genetic counseling for affected families.
- Test Code
- 5030
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 Weeks
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
Provide clinical history of the patient, including symptoms and family history of immunological disorders. A genetic counseling session is recommended to draw a pedigree chart of affected family members.
Method: Venipuncture or Finger Prick
Laboratory Analysis
Blood sample will be collected via venipuncture or finger prick. For FTA card, one drop of blood is applied.
Report Delivery
Sample is sent to the laboratory for NGS analysis. Results are available in 3 to 4 weeks.
Timeline: 3 to 4 Weeks
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the PICALM Gene NGS Genetic Test is to identify pathogenic mutations in the PICALM gene that may cause or predispose individuals to immunological disorders such as Alzheimer's disease and leukemia. This test aids healthcare providers in making accurate diagnoses, guiding treatment decisions, and facilitating genetic counseling for affected families.
How to Prepare
- Ensure proper identification of the patient
- Use sterile equipment for blood collection
- Label samples correctly with patient details
- Store samples at ambient room temperature if not processed immediately
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Genetic testing for PICALM gene mutations is crucial for early diagnosis and management of immunological disorders, especially in patients with family history or symptoms suggestive of Alzheimer's or leukemia."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted samples
- Insufficient sample volume
- Incorrect labeling or missing patient information
Understanding Your Results
Positive for pathogenic variant
A mutation known to cause disease was detected. Consult a genetic counselor for management and family testing.
Negative
No pathogenic variants were detected. Clinical correlation is advised if symptoms persist.
Variant of uncertain significance (VUS)
A genetic variant was found, but its clinical significance is unknown. Further testing or family studies may be needed.
Consult a doctor if you experience symptoms such as memory loss, confusion, fatigue, fever, weight loss, joint pain, abdominal pain, shortness of breath, or easy bruising, especially with a family history of Alzheimer's disease or leukemia.
Limitations
- ⚠This test may not detect all possible mutations in the PICALM gene
- ⚠Results require clinical correlation and genetic counseling
- ⚠Turnaround time may vary based on laboratory workload
Risks & Considerations
- ●Minimal risk from blood draw, such as bruising or infection
- ●Psychological impact of genetic results
- ●Potential for uncertain results requiring further evaluation
Interfering Factors
- ●Contaminated or degraded DNA samples
- ●Recent blood transfusions may affect results
- ●Technical errors in sample collection or processing
Frequently Asked Questions
What is the PICALM Gene NGS Genetic Test?
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What is the cost of the test?
How is the sample collected?
Is fasting required before the test?
How long does it take to get results?
What do the results mean?
Is the test accurate?
Can this test diagnose Alzheimer's disease?
Is home sample collection available?
What are the risks of the test?
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Related Tests
Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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