PIK3CD Gene Immunodeficiency type 14 NGS Genetic Test
Short Name: PIK3CD Immunodeficiency Type 14 Test
Also known as: PIK3CD deficiency, Immunodeficiency type 14, Activated PI3K-delta syndrome
PIK3CD Gene Immunodeficiency type 14 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of the PIK3CD Gene Immunodeficiency Type 14 NGS Genetic Test is to diagnose mutations in the PIK3CD gene associated with immunodeficiency type 14, enabling early detection, appropriate treatment planning, and genetic counseling for affected individuals and families.
- Test Code
- 5003
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 Weeks
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
Provide clinical history and undergo genetic counseling to draw a pedigree chart of affected family members.
Method: Venipuncture
Laboratory Analysis
A blood sample will be collected by a healthcare professional via venipuncture or using an FTA card for one drop of blood.
Report Delivery
Apply pressure to the puncture site to prevent bleeding. Store the sample as instructed and await report delivery in 3 to 4 weeks.
Timeline: 3 to 4 Weeks
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the PIK3CD Gene Immunodeficiency Type 14 NGS Genetic Test is to diagnose mutations in the PIK3CD gene associated with immunodeficiency type 14, enabling early detection, appropriate treatment planning, and genetic counseling for affected individuals and families.
How to Prepare
- Ensure patient is relaxed and hydrated
- Use sterile equipment for blood collection
- Label the sample correctly with patient details
- Transport the sample at ambient room temperature
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Early genetic testing for PIK3CD mutations can guide treatment and improve outcomes for patients with immunodeficiency, especially in cases with recurrent infections or autoimmune symptoms."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted blood sample
- Insufficient sample volume
- Incorrect labeling or missing patient information
Understanding Your Results
Positive for pathogenic variant
Confirms diagnosis of PIK3CD gene immunodeficiency type 14. Recommend clinical management and genetic counseling.
Negative for pathogenic variant
No mutations detected. Consider other genetic or non-genetic causes if symptoms persist.
Variant of uncertain significance
Further testing and family studies may be needed for clarification.
Consult a doctor if you experience recurrent infections, autoimmune symptoms, or have a family history of immunodeficiency. After testing, discuss results with a geneticist or immunologist for personalized care.
Limitations
- ⚠May not detect all genetic variants or novel mutations
- ⚠Requires genetic counseling for interpretation
- ⚠Results should be correlated with clinical symptoms and family history
Risks & Considerations
- ●Minimal risk from blood draw, such as slight pain, bruising, or infection at the puncture site
Interfering Factors
- ●Contaminated or degraded DNA sample
- ●Improper sample collection or storage
- ●Recent blood transfusions affecting DNA integrity
Compare With Similar Tests
| Test | PIK3CD Gene Immunodeficiency type 14 NGS Genetic Test | PIK3R1 Gene Test | BTK Gene Test | Common Variable Immunodeficiency Panel | Primary Immunodeficiency Comprehensive Panel |
|---|---|---|---|---|---|
| Comparison | PIK3CD Gene Immunodeficiency type 14 NGS Genetic Test | Tests for mutations in PIK3R1 gene, associated with similar immunodeficiency disorders. | Diagnoses X-linked agammaglobulinemia, another primary immunodeficiency. | Screens multiple genes linked to common variable immunodeficiency. | Broad panel testing for various primary immunodeficiency disorders. |
Frequently Asked Questions
What is PIK3CD Gene Immunodeficiency Type 14?
What are the common symptoms of this condition?
How is PIK3CD Immunodeficiency Type 14 diagnosed?
What is the cost of the PIK3CD Genetic Test at DNA Labs India?
Is home sample collection available for this test?
How long does it take to receive the test results?
What does a positive test result mean?
Can children undergo this genetic test?
Is genetic counseling required before testing?
What are the treatment options for PIK3CD Immunodeficiency?
Is this test covered by insurance or government schemes?
How accurate is the NGS genetic test for PIK3CD mutations?
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