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DNA Labs India

PLA2G6 Gene PARK14 Parkinson NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

PLA2G6 Gene PARK14 Parkinson NGS Genetic Test

Short Name: PLA2G6 PARK14 Test

Also known as: PLA2G6 Gene Test, PARK14 Parkinson Test, Parkinson's Genetic Test, Neurodegenerative Genetic Test

PLA2G6 Gene PARK14 Parkinson NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in Results typically available in 3 to 4 weeks after sample receipt.. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

The purpose of this test is to detect mutations in the PLA2G6 gene associated with PARK14-linked parkinsonism, facilitating early diagnosis, genetic counseling, and personalized treatment strategies for Parkinson's disease.

Test Code
1783
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
Results typically available in 3 to 4 weeks after sample receipt.
Fasting Required
No
Method
Next-Generation Sequencing (NGS)
Step 1

Sample Collection

No specific preparation required. Provide clinical history and undergo genetic counseling if recommended.

Method: Venipuncture or finger-prick for FTA card

Step 2

Laboratory Analysis

Blood sample collected via venipuncture or finger-prick for FTA card by a trained professional.

Step 3

Report Delivery

Apply pressure to the collection site to prevent bruising. Store samples as directed.

Timeline: Results typically available in 3 to 4 weeks after sample receipt.

Patient Instructions

1
Before the Test:Discuss with a healthcare provider about the need for genetic testing. Provide informed consent and clinical history.
2
During the Test:Sample collection (blood or saliva) is performed. The process is minimally invasive with no special requirements.
3
After the Test:Results are delivered within 3-4 weeks. Follow-up with a doctor for interpretation and next steps.

About This Test

Who Should Get This Test

The purpose of this test is to detect mutations in the PLA2G6 gene associated with PARK14-linked parkinsonism, facilitating early diagnosis, genetic counseling, and personalized treatment strategies for Parkinson's disease.

How to Prepare

  • Ensure proper identification of patient and sample
  • Use sterile equipment for blood collection
  • Label samples accurately with patient details
  • Transport samples at ambient room temperature unless specified

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Early genetic testing for PLA2G6 mutations can guide personalized management in familial Parkinson's cases, potentially improving quality of life through targeted interventions."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Sample Volume3-5 mL blood or equivalent
ContainerEDTA tube or FTA card
Collection MethodVenipuncture or finger-prick for FTA card

Sample Stability

Blood samples stable at room temperature for 24 hours
FTA cards stable at room temperature for extended periods
Extracted DNA stable at -20°C for long-term storage
Sample Rejection Criteria:
  • Hemolyzed or clotted blood samples
  • Insufficient sample volume
  • Improperly labeled or unlabeled samples
  • Contaminated samples

Understanding Your Results

Results from the PLA2G6 Gene PARK14 Parkinson NGS Genetic Test indicate the presence or absence of mutations in the PLA2G6 gene. A positive result suggests a genetic predisposition to PARK14-linked parkinsonism, while a negative result means no pathogenic variants were detected. Genetic counseling is recommended to understand implications.
Positive result: Pathogenic variant detected, indicating increased risk for PARK14-linked parkinsonism; clinical correlation and family testing advised
Negative result: No pathogenic variants found; however, does not rule out other genetic causes of Parkinson's
Variant of uncertain significance: Further testing or family studies may be needed for clarification
Inconclusive result: Repeat testing or alternative methods may be required
⚠️ When to Consult a Doctor:

Consult a neurologist or genetic specialist if test results are positive, inconclusive, or if symptoms persist despite negative results. Early consultation helps in management planning.

Limitations

  • ⚠Test may not detect all possible mutations in the PLA2G6 gene
  • ⚠Results should be interpreted in conjunction with clinical evaluation
  • ⚠Does not diagnose other forms of Parkinson's disease

Risks & Considerations

  • ●Minimal risk from blood draw, such as bruising or infection
  • ●No significant risks associated with genetic testing itself
  • ●Psychological impact of results may require counseling

Interfering Factors

  • ●Contaminated or degraded DNA samples
  • ●Recent blood transfusion may affect results
  • ●Incorrect sample collection or storage

Compare With Similar Tests

TestPLA2G6 Gene PARK14 Parkinson NGS Genetic TestLRRK2 Gene TestSNCA Gene TestPARK2 Gene TestParkinson's Disease Genetic Panel
ComparisonPLA2G6 Gene PARK14 Parkinson NGS Genetic Test

Frequently Asked Questions

What is the PLA2G6 Gene PARK14 Parkinson NGS Genetic Test?
This test uses Next-Generation Sequencing to detect mutations in the PLA2G6 gene, associated with PARK14-linked parkinsonism, a rare form of Parkinson's disease.
Who should consider getting this test?
Individuals with a family history of PARK14, early-onset Parkinson's symptoms (before age 40), or clinical features like dystonia and cognitive impairment should consider testing.
What is the cost of the PLA2G6 Gene test?
The test costs INR 20,000 at DNA Labs India, including sample collection, analysis, and a detailed report.
How is the test performed?
The test analyzes DNA from a blood or saliva sample using NGS technology. Sample collection can be done at home or in-lab.
What samples are accepted for the test?
Accepted samples include blood, extracted DNA, or one drop of blood on an FTA card.
How long does it take to get the test results?
Results are typically available within 3 to 4 weeks after sample collection.
Is home sample collection available for this test?
Yes, DNA Labs India offers free home sample collection across India for online bookings.
What does a positive test result indicate?
A positive result means a pathogenic mutation in the PLA2G6 gene was detected, indicating a genetic risk for PARK14-linked parkinsonism. Consult a neurologist for further evaluation and management planning.
Can this test diagnose other types of Parkinson's disease?
No, this test specifically targets the PLA2G6 gene for PARK14. Other genetic tests are available for different forms of Parkinson's.
Is genetic counseling recommended before or after the test?
Yes, genetic counseling is advised to understand the implications of testing and results, and to draw a family pedigree chart.
What are the treatment options based on test results?
Treatment is personalized and may include medications, therapies, and lifestyle changes. Early diagnosis can help manage symptoms effectively.
What should I do if the test results are inconclusive?
If results are inconclusive, consult a genetic specialist for possible retesting or additional family studies to clarify findings.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

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Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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