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DNA Labs India

Pol Gene Mutation Analysis Test

DNA Labs India | ISO 9001:2015 Certified

Pol Gene Mutation Analysis Test

Also known as: HIV Pol Gene Test, Polymerase Gene Mutation Analysis

Pol Gene Mutation Analysis Test test available at DNA Labs India for ₹10,500. Uses Sanger Sequencing on Tumor tissue samples. Results in 8-9 days. Free home collection in 300+ cities across India.

Genetic Test🏠 Home Collection

🩺 Medically Reviewed By

Overview

To detect mutations in the HIV Pol gene that confer resistance to antiretroviral drugs, aiding in treatment optimization and personalized therapy for HIV patients.

Test Code
3155
Price
₹10,500
Sample Type
Tumor tissue
Result Time
8-9 days
Fasting Required
No
Method
Sanger Sequencing
Step 1

Sample Collection

A doctor's prescription is required. Not applicable for surgery, pregnancy, or travel abroad cases. Ensure proper sample collection instructions are followed.

Step 2

Laboratory Analysis

Sample collection by trained phlebotomist or healthcare provider using sterile techniques.

Step 3

Report Delivery

Store sample appropriately and transport to lab within stability period.

Timeline: 8-9 days

Patient Instructions

1
Before the Test:Obtain a doctor's prescription. No fasting required. Inform lab of any medications or health conditions.
2
During the Test:Sample collection procedure is quick and minimally invasive.
3
After the Test:Resume normal activities. Results will be available in 8-9 days.

About This Test

Who Should Get This Test

To detect mutations in the HIV Pol gene that confer resistance to antiretroviral drugs, aiding in treatment optimization and personalized therapy for HIV patients.

How to Prepare

  • Use sterile containers
  • Label samples with patient details
  • Avoid hemolysis
  • Follow aseptic techniques

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"As an obstetrician, I recommend Pol gene mutation analysis for pregnant women with HIV to ensure effective treatment and prevent mother-to-child transmission."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeTumor tissue

Sample Stability

Store at -20°C for long-term stability
Transport at 2-8°C
Sample Rejection Criteria:
  • Insufficient sample volume
  • Hemolyzed or contaminated sample
  • Improper labeling

Understanding Your Results

Results indicate the presence or absence of mutations in the Pol gene, which may affect HIV treatment efficacy.
Positive: Mutations detected, indicating potential drug resistance. Consult specialist for treatment adjustment.
Negative: No mutations detected, suggesting susceptibility to current antiretroviral drugs.
Inconclusive: Repeat testing or additional tests recommended.
⚠️ When to Consult a Doctor:

If mutations are detected or if there is treatment failure, consult your HIV specialist immediately for therapy modification.

Limitations

  • May not detect all rare mutations
  • Requires confirmatory testing for clinical decisions
  • Limited to known mutation profiles

Risks & Considerations

  • Minimal risk from blood draw
  • Psychological impact of results
  • False positives/negatives possible

Interfering Factors

  • Sample contamination
  • Improper sample storage
  • Recent antiviral therapy

Frequently Asked Questions

What is Pol Gene Mutation Analysis?
It is a test that detects mutations in the HIV polymerase gene, which can indicate drug resistance.
Why is this test important for HIV patients?
It helps determine if HIV has developed resistance to antiretroviral drugs, guiding treatment decisions.
How is the test performed?
The test uses Sanger Sequencing on a tumor tissue sample to identify Pol gene mutations.
What is the cost of the test?
The cost is INR 10500 at DNA Labs India, with free home sample collection.
Is home collection available?
Yes, free home sample collection is available across many cities in India.
How long does it take to get results?
Results are typically available in 8-9 days.
What do the results mean?
Positive results indicate mutations that may cause drug resistance; negative results suggest no resistance.
Is a prescription required?
Yes, a doctor's prescription is required, except for surgery, pregnancy, or travel abroad cases.
Are there any risks?
Risks are minimal, similar to a blood draw, but psychological impact of results is possible.
How accurate is the test?
The test is highly accurate using Sanger Sequencing, but confirmatory testing may be needed.
Can the test be done during pregnancy?
Yes, but a prescription is not required for pregnancy cases; consult your doctor for guidance.
What should I do if mutations are detected?
Consult your HIV specialist immediately to adjust treatment based on resistance profile.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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