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TLR5 Gene Legionnaire disease, susceptibility to NGS Genetic Test

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TLR5 Gene Legionnaire disease, susceptibility to NGS Genetic Test

Short Name: TLR5 Gene Legionnaire Disease Susceptibility Test

Also known as: TLR5 Gene Test, Legionnaire Disease Genetic Test, Legionellosis Susceptibility Test

TLR5 Gene Legionnaire disease, susceptibility to NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood, Extracted DNA, or One drop Blood on FTA Card samples. Results in 3-4 weeks. Free home collection in 300+ cities across India.

Next-Generation Sequencing (NGS)All Ages🏠 Home Collection

🩺 Medically Reviewed By

Overview

To identify genetic variations in the TLR5 gene that may increase susceptibility to Legionnaire disease, allowing for risk assessment and preventive health measures.

Test Code
2752
Price
₹20,000
Sample Type
Blood, Extracted DNA, or One drop Blood on FTA Card
Result Time
3-4 weeks
Fasting Required
No
Method
Next-Generation Sequencing (NGS)
Step 1

Sample Collection

No special preparation required. Provide clinical history and genetic counseling information.

Method: Venipuncture or finger prick

Step 2

Laboratory Analysis

Standard blood draw procedure using aseptic technique.

Step 3

Report Delivery

Apply pressure to the puncture site to prevent bleeding. Store sample as instructed.

Timeline: 3-4 weeks

Patient Instructions

1
Before the Test:Provide clinical history and undergo genetic counseling session to draw a pedigree chart.
2
During the Test:Sample collection via blood draw or FTA card.
3
After the Test:Results delivered in 3-4 weeks; follow-up with healthcare provider recommended.

About This Test

Who Should Get This Test

To identify genetic variations in the TLR5 gene that may increase susceptibility to Legionnaire disease, allowing for risk assessment and preventive health measures.

How to Prepare

  • Ensure sample is collected in appropriate container
  • Label sample correctly with patient details
  • Transport sample at ambient room temperature

Doctor's Notes

Reviewed by — MBBS, MD (General Medicine) · Reg. No. 8052

"This test identifies genetic variations in the TLR5 gene that may increase susceptibility to Legionnaire disease, enabling preventive strategies and personalized health management."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood, Extracted DNA, or One drop Blood on FTA Card
Sample Volume5 mL blood or equivalent
ContainerEDTA tube or FTA card
Collection MethodVenipuncture or finger prick

Sample Stability

Blood samples stable for 48 hours at room temperature
Extracted DNA stable for longer periods if stored properly
Sample Rejection Criteria:
  • Hemolyzed or clotted samples
  • Insufficient sample volume
  • Incorrect labeling or container

Understanding Your Results

Results indicate the presence or absence of genetic variations in the TLR5 gene associated with increased risk for Legionnaire disease.
Positive for variant: Increased genetic susceptibility to Legionnaire disease
Negative: No increased genetic risk identified
Variant of uncertain significance: Further evaluation may be needed
⚠️ When to Consult a Doctor:

If you have symptoms of Legionnaire disease, a family history, or test positive for a variant, consult a healthcare provider for personalized advice.

Limitations

  • Does not diagnose active Legionnaire disease infection
  • Only assesses genetic susceptibility, not environmental factors
  • Results may not predict disease severity

Risks & Considerations

  • Minimal risk of infection or bruising from blood draw
  • Potential psychological impact of genetic results

Interfering Factors

  • Sample contamination
  • Improper storage or handling of sample
  • Recent blood transfusion

Frequently Asked Questions

What is the TLR5 Gene Legionnaire Disease Susceptibility Test?
It is a genetic test that analyzes variations in the TLR5 gene to assess susceptibility to Legionnaire disease using Next-Generation Sequencing (NGS).
How is the test performed?
A blood sample or extracted DNA is collected and analyzed using NGS technology to identify genetic variants in the TLR5 gene.
What is the cost of the test?
The test costs INR 20000, which includes home sample collection across India.
Is home sample collection available?
Yes, free home sample collection is available for online bookings in numerous cities across India.
How long does it take to get results?
Results are typically available in 3-4 weeks after sample collection.
What do the results mean?
Results indicate whether you have genetic variations in the TLR5 gene that may increase your risk for Legionnaire disease. A positive result suggests increased susceptibility.
Who should take this test?
Individuals with a family history of Legionnaire disease, immunocompromised conditions, or those concerned about genetic susceptibility.
Is the test covered by insurance?
Coverage depends on your insurance plan; it is not typically covered under government schemes like PMJAY or CGHS. Check with your provider.
What are the risks of the test?
Risks are minimal, including slight discomfort from blood draw and potential psychological impact of genetic results.
How accurate is the test?
The test uses advanced NGS technology for high accuracy in detecting genetic variants, but it assesses susceptibility, not disease diagnosis.
Can I get genetic counseling with the test?
Yes, genetic counseling is included to help interpret results and draw a family pedigree chart.
What should I do if I test positive for a variant?
Consult your healthcare provider to discuss preventive measures, such as avoiding high-risk environments and monitoring for symptoms.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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