Prothrombin Gene Mutation Analysis Test
Short Name: PSA Profile
Also known as: PSA Profile, Prostate-Specific Antigen Profile, Total and Free PSA
Prothrombin Gene Mutation Analysis Test test available at DNA Labs India for ₹1,697. Uses Chemiluminescent Microparticle Immunoassay (CMIA) on Serum samples. Results in Reports are generated by the laboratory daily and are usually available on the same day or next day depending on collection time.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
This assay aids in the early detection of prostate cancer in males 50 years or older with total PSA values between 4.0 and 10.0 ng/mL and non-suspicious digital rectal examination. It also discriminates between prostate cancer and benign prostatic disease. Patients with benign conditions have a higher proportion of free PSA compared with prostate cancer.
- Test Code
- 3579
- Price
- ₹1,697
- Sample Type
- Serum
- Result Time
- Reports are generated by the laboratory daily and are usually available on the same day or next day depending on collection time.
- Fasting Required
- No
- Method
- Chemiluminescent Microparticle Immunoassay (CMIA)
Sample Collection
Do not give a sample within 7 days of Digital Rectal Examination (DRE) or Rectal Prostatic Ultrasonography. No fasting is required. Inform your doctor about recent urinary symptoms, infections, or urological procedures.
Method: Venipuncture
Laboratory Analysis
A trained phlebotomist will collect a blood sample from a vein in your arm. The procedure is quick and routine.
Report Delivery
You can resume normal activities immediately. If bruising or discomfort occurs at the puncture site, apply gentle pressure; notify the lab if bleeding persists.
Timeline: Reports are generated by the laboratory daily and are usually available on the same day or next day depending on collection time.
Patient Instructions
About This Test
Who Should Get This Test
This assay aids in the early detection of prostate cancer in males 50 years or older with total PSA values between 4.0 and 10.0 ng/mL and non-suspicious digital rectal examination. It also discriminates between prostate cancer and benign prostatic disease. Patients with benign conditions have a higher proportion of free PSA compared with prostate cancer.
How to Prepare
- Do not give blood within 7 days of Digital Rectal Examination (DRE) or Rectal Prostatic Ultrasonography.
- No fasting is required.
- Inform the laboratory if you have had any recent urological procedure or infection.
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"PSA results are not cancer-specific; they must be interpreted together with DRE, age, and other risk factors."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Sample collected within 7 days of DRE or rectal prostatic ultrasonography
- Haemolysed or lipemic sample
- Insufficient sample volume
- Improperly labelled or transported sample
Understanding Your Results
Consult your doctor if you experience frequent urination, especially at night, difficulty starting or stopping urination, weak or interrupted urine flow, blood in urine or semen, pain during ejaculation, or persistent lower back, hip, or thigh pain. Also consult if your PSA level is elevated.
Limitations
- ⚠PSA is prostate-specific, not cancer-specific; elevated levels can occur in benign conditions.
- ⚠There is no absolute PSA cutoff that fully excludes or confirms prostate cancer.
- ⚠Free/total PSA ratio is most useful when total PSA is between 4.0 and 10.0 ng/mL.
- ⚠This test alone cannot diagnose prostate cancer; biopsy is needed for confirmation.
- ⚠Results must be interpreted by a qualified doctor along with DRE and clinical history.
Risks & Considerations
- ●Minor pain or bruising at the needle site
- ●Dizziness during or after blood draw
- ●Very small risk of infection
Interfering Factors
- ●Digital rectal examination (DRE) within the past 7 days
- ●Rectal prostatic ultrasonography within the past 7 days
- ●Acute urinary tract infection or prostatitis
- ●Benign prostatic hyperplasia (BPH)
- ●Recent ejaculation can transiently raise PSA
Compare With Similar Tests
| Test | Prothrombin Gene Mutation Analysis Test | |||
|---|---|---|---|---|
| Comparison | Prothrombin Gene Mutation Analysis Test | A blood test measuring total PSA, free PSA, and ratio; used for screening and monitoring. | A physical exam of the prostate; recommended alongside PSA to assess prostate cancer risk. | An invasive procedure that removes tissue for microscopic examination; confirms the presence of cancer. |
Frequently Asked Questions
What is a PSA Profile test?
What is the price of the PSA Profile test at DNA Labs India?
Is fasting required for the PSA Profile test?
Can I give a blood sample within 7 days after a digital rectal examination?
What is the normal total PSA level?
Why is free/total PSA ratio important?
Who should take the PSA Profile test?
How soon will I get my PSA Profile report?
Does DNA Labs India provide home sample collection for this test?
Can a PSA Profile test alone detect prostate cancer?
What sample is needed for the PSA Profile test?
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