PSA Profile Test
Short Name: PSA Free Test
Also known as: PSA Free Test, Free PSA Test, Prostate-Specific Antigen Free Test, PSA Profile
PSA Profile Test test available at DNA Labs India for ₹995. Uses Chemiluminescent Microparticle Immunoassay on Serum samples. Results in Reports are typically available within the same day or as per your laboratory's turnaround time. You will be notified via SMS/email when the report is ready.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The PSA Profile Test is performed to evaluate the levels of total and free PSA in the blood, helping clinicians assess the likelihood of prostate cancer. It is particularly useful in distinguishing prostate cancer from benign prostate conditions when total PSA is mildly elevated. The free PSA percentage adds diagnostic clarity and reduces unnecessary biopsies.
- Test Code
- 3580
- Price
- ₹995
- Sample Type
- Serum
- Result Time
- Reports are typically available within the same day or as per your laboratory's turnaround time. You will be notified via SMS/email when the report is ready.
- Fasting Required
- No
- Method
- Chemiluminescent Microparticle Immunoassay
Sample Collection
Do not give a blood sample within 7 days of Digital Rectal Examination (DRE) or Rectal Prostatic Ultrasonography. Inform your doctor about any recent procedures, infections, or medications.
Method: Blood Draw
Laboratory Analysis
A trained phlebotomist will draw blood from a vein in your arm. The process takes only a few minutes and involves minimal discomfort.
Report Delivery
No specific precautions are required after blood collection. You can resume normal activities immediately.
Timeline: Reports are typically available within the same day or as per your laboratory's turnaround time. You will be notified via SMS/email when the report is ready.
Patient Instructions
About This Test
Who Should Get This Test
The PSA Profile Test is performed to evaluate the levels of total and free PSA in the blood, helping clinicians assess the likelihood of prostate cancer. It is particularly useful in distinguishing prostate cancer from benign prostate conditions when total PSA is mildly elevated. The free PSA percentage adds diagnostic clarity and reduces unnecessary biopsies.
How to Prepare
- Do not collect the sample within 7 days of DRE or rectal ultrasonography.
- No fasting is required for this test.
- Ensure you are well-hydrated before the blood draw.
- Inform the lab if you have any bleeding disorders or are on anticoagulant therapy.
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"PSA screening is essential for early detection of prostate cancer. The free PSA fraction adds valuable diagnostic information when total PSA is borderline. - DNALABS-PHYSICIAN"
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Sample received after more than 2 hours at room temperature
- Hemolysed or lipemic sample
- Improperly labelled specimen
- Sample collected within 7 days of Digital Rectal Examination (DRE) or Rectal Ultrasonography
Understanding Your Results
Low probability of prostate cancer; follow routine screening as recommended.
Low risk of prostate cancer; further evaluation may not be required immediately, but clinical correlation is advised.
Equivocal risk; additional tests like MRI or prostate biopsy may be considered.
High risk of prostate cancer; prostate biopsy is strongly recommended.
High probability of prostate cancer; prompt urological consultation and biopsy recommended.
If your PSA profile shows elevated total PSA or a low free PSA percentage, consult an oncologist or urologist promptly. Do not delay, as early evaluation is crucial for successful treatment. Persistent urinary symptoms or bone pain also warrant immediate medical advice.
Limitations
- ⚠PSA is prostate-specific but not cancer-specific; elevated levels can be due to benign conditions like BPH or prostatitis.
- ⚠A normal PSA does not completely exclude the possibility of prostate cancer.
- ⚠Free PSA percentage is most informative only when total PSA is between 4 and 10 ng/mL.
- ⚠Reference ranges may vary between laboratories; results should be interpreted by a qualified clinician.
- ⚠This test is not a confirmatory test for prostate cancer; biopsy is required for histopathological diagnosis.
Risks & Considerations
- ●Minimal risk of bleeding, bruising, or infection at the needle puncture site
- ●Fainting or dizziness during blood draw (rare)
- ●Elevated PSA due to recent DRE if instructions are not followed
Interfering Factors
- ●Digital Rectal Examination (DRE) can cause transient elevation of PSA; hence sample must be collected before DRE or at least 7 days after.
- ●Rectal Prostatic Ultrasonography may similarly affect PSA levels.
- ●Recent ejaculation may cause mild elevation of PSA.
- ●Urinary tract infection or acute bacterial prostatitis can elevate PSA significantly.
- ●Heavy physical exertion, such as bicycle riding, may also affect PSA levels.
- ●Medications like 5-alpha-reductase inhibitors (e.g., finasteride) can lower PSA levels.
Compare With Similar Tests
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Frequently Asked Questions
What is the PSA Profile Test?
How much does the PSA Profile Test cost at DNA Labs India?
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Is fasting required for the PSA Profile Test?
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What does a high total PSA level mean?
How is the free PSA ratio interpreted?
Can the PSA Profile Test diagnose prostate cancer?
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