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RABGGTA Gene Autism Spectrum Disorder NGS Genetic Test

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RABGGTA Gene Autism Spectrum Disorder NGS Genetic Test

Short Name: RABGGTA Gene ASD NGS Test

Also known as: RABGGTA Gene Sequencing, Autism Spectrum Disorder NGS Panel, RABGGTA ASD Genetic Test

RABGGTA Gene Autism Spectrum Disorder NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in Results are typically delivered within 3 to 4 weeks after the sample reaches the laboratory. The report includes variant details, classification, and downloadable raw data files (FASTQ, VCF).. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

The purpose of the RABGGTA gene NGS genetic test is to identify pathogenic mutations in the RABGGTA gene that may be associated with Autism Spectrum Disorder. This test aids clinicians in establishing a molecular diagnosis, guiding appropriate management, enabling early intervention, and facilitating informed genetic counseling for the patient and family members.

Test Code
3897
CPT Code
81479
ICD Code
F84.0
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
Results are typically delivered within 3 to 4 weeks after the sample reaches the laboratory. The report includes variant details, classification, and downloadable raw data files (FASTQ, VCF).
Fasting Required
No
Method
Next-Generation Sequencing (NGS)
Step 1

Sample Collection

No special preparation, including fasting, is required. Please carry any previous genetic test reports, clinical history, and physician referral if available. A genetic counseling session will be conducted to draw a pedigree chart.

Method: Peripheral blood draw or FTA card spot

Step 2

Laboratory Analysis

For blood sample, a standard peripheral blood draw is performed. If using FTA card, a small drop of blood is applied onto the card. The process is painless and takes about 5 minutes.

Step 3

Report Delivery

You may resume normal activities immediately. The collected sample will be transported to our accredited laboratory. Reports will be shared via email/WhatsApp within the turnaround time.

Timeline: Results are typically delivered within 3 to 4 weeks after the sample reaches the laboratory. The report includes variant details, classification, and downloadable raw data files (FASTQ, VCF).

Patient Instructions

1
Before the Test:Before booking the test, the patient or family may undergo a genetic counseling session to understand the purpose, limitations, and expected outcomes. A detailed clinical history and pedigree chart of family members affected with ASD or related neurological conditions will be recorded.
2
During the Test:During the test, a sample of blood or extracted DNA is collected. The DNA is then sequenced using NGS technology. The laboratory process involves library preparation, enrichment, sequencing, and bioinformatics analysis. No invasive procedures are required for the patient apart from a simple blood draw.
3
After the Test:After the test, the results are reviewed and interpreted by a clinical geneticist. The report will be delivered through the chosen communication channel. Follow-up genetic counseling is recommended to discuss the findings and their implications for the patient and family.

About This Test

Who Should Get This Test

The purpose of the RABGGTA gene NGS genetic test is to identify pathogenic mutations in the RABGGTA gene that may be associated with Autism Spectrum Disorder. This test aids clinicians in establishing a molecular diagnosis, guiding appropriate management, enabling early intervention, and facilitating informed genetic counseling for the patient and family members.

How to Prepare

  • Use EDTA vacutainer for blood collection
  • For FTA card, ensure the card is properly labeled and dried
  • Samples should be transported at room temperature
  • Do not freeze whole blood; extracted DNA should be stored at -20°C

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"A multidisciplinary approach with pediatric neurology and clinical genetics is recommended to interpret this test, assess developmental milestones, and guide early intervention and family counseling."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Sample Volume5 ml blood or 2 µg extracted DNA
ContainerEDTA vacutainer or DNA extraction kit
Collection MethodPeripheral blood draw or FTA card spot

Sample Stability

Sample Rejection Criteria:
  • Clotted or hemolyzed blood samples
  • Improperly labeled samples
  • Insufficient DNA quantity or quality
  • Samples received in non-EDTA tubes (heparin or citrate)

Understanding Your Results

The result of the RABGGTA gene analysis is interpreted by a clinical geneticist. A pathogenic variant indicates a genetic contribution to the ASD phenotype and supports a molecular diagnosis. A negative result does not exclude ASD as other genetic or non-genetic causes may be responsible.
📊

Pathogenic variant detected

Variant is disease-causing and likely contributes to ASD. Genetic counseling recommended.

📊

Likely pathogenic variant detected

Variant is likely disease-causing but additional evidence may be needed. Clinical correlation advised.

📊

Variant of uncertain significance (VUS)

Variant cannot be classified as benign or pathogenic. Further family studies may help.

📊

No pathogenic variant detected

No disease-associated variant found in the RABGGTA gene. Does not rule out ASD.

⚠️ When to Consult a Doctor:

If the test identifies a pathogenic or likely pathogenic variant, please consult a clinical geneticist and a neurologist/developmental pediatrician for further management, surveillance, and family counseling.

Limitations

  • ⚠This test does not detect all genetic causes of ASD
  • ⚠Variants of uncertain significance may require further testing or family segregation analysis
  • ⚠Non-genetic and environmental factors are not evaluated
  • ⚠The test is limited to the RABGGTA gene and does not screen other ASD-related genes

Risks & Considerations

  • ●Minimal risk of bruising or bleeding at the puncture site
  • ●Slight discomfort during blood draw
  • ●Rare risk of infection (very low)
  • ●Fainting or dizziness in rare cases

Interfering Factors

  • ●Poor DNA quality or quantity from sample
  • ●Contamination during sample collection or processing
  • ●Incomplete clinical information restricting interpretation
  • ●Presence of mosaic variants below sequencing depth threshold

Compare With Similar Tests

TestRABGGTA Gene Autism Spectrum Disorder NGS Genetic TestSingle Gene SequencingASD NGS PanelWhole Exome Sequencing
ComparisonRABGGTA Gene Autism Spectrum Disorder NGS Genetic Test

Frequently Asked Questions

What is the RABGGTA gene?
The RABGGTA gene encodes the alpha subunit of Rab geranylgeranyltransferase, an enzyme involved in the prenylation of Rab GTPases. This process is essential for intracellular vesicle trafficking and signaling. Mutations in this gene have been studied in relation to Autism Spectrum Disorder.
How is Autism Spectrum Disorder diagnosed?
ASD is typically diagnosed through a comprehensive evaluation by a qualified healthcare professional, including behavioral observation, developmental and medical history review, psychological and cognitive assessments, and sometimes genetic testing to identify an underlying cause.
What is the cost of the RABGGTA gene NGS genetic test at DNA Labs India?
The special discounted price for the RABGGTA Gene Autism Spectrum Disorder NGS Genetic Test at DNA Labs India is INR 20000. This includes free home sample collection in many cities across India.
What sample is required for this test?
The sample can be either 5 ml of blood in an EDTA tube, 2 micrograms of extracted DNA, or a few drops of blood on an FTA card. All sample types are acceptable for NGS analysis.
Do I need to fast before the test?
No, fasting is not required for this genetic test. You can eat and drink normally before sample collection.
How long will it take to get the test reports?
Reports are typically available within 3 to 4 weeks after the sample is received at the laboratory. You will be notified via email or WhatsApp when the report is ready.
What is Next-Generation Sequencing (NGS)?
NGS is an advanced DNA sequencing technology that can analyze multiple genes simultaneously with high accuracy. It allows detection of mutations and variations across the entire coding region of a gene.
Will I get raw data files like FASTQ and VCF?
Yes, DNA Labs India is transparent and provides raw data files (FASTQ, VCF, and BAM) along with the conclusive clinical report. We believe in full transparency for improved patient care.
Does DNA Labs India provide home sample collection?
Yes, we offer free home sample collection for online bookings of the RABGGTA Gene ASD NGS Genetic Test. The service is available in more than 300 cities across India, including Mumbai, Delhi, Bangalore, Hyderabad, Chennai, Kolkata, and many more.
Is genetic counseling required before the test?
A genetic counseling session is recommended and is included in the test process. Our genetic counselor will draw a pedigree chart and discuss clinical history, helping to contextualize the test results.
What are the common symptoms of Autism Spectrum Disorder?
Common symptoms include delayed or absent language development, poor eye contact, difficulty in social interaction, repetitive behaviors, unusual sensory processing, and difficulty understanding others' emotions.
Can this test definitively diagnose Autism Spectrum Disorder?
No, this test does not diagnose ASD by itself. ASD is diagnosed clinically. The RABGGTA gene test helps identify a genetic cause, which can support the clinical diagnosis and guide management. A negative result does not rule out ASD.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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