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DNA Labs India

Sex Hormone Binding Globulin SHBG Test

DNA Labs India | ISO 9001:2015 Certified

Sex Hormone Binding Globulin SHBG Test

Short Name: SHBG Test

Also known as: SHBG, Sex Hormone Binding Globulin Test

Sex Hormone Binding Globulin SHBG Test test available at DNA Labs India for ₹2,750. Uses Chemiluminescent Immunoassay on Serum samples. Results in Reports are delivered the same day if the sample is received by 4 pm on Monday or Thursday.. Free home collection in 300+ cities across India.

EndocrinologistAll Ages🏠 Home Collection

🩺 Medically Reviewed By

Overview

To assess SHBG levels and help diagnose and monitor conditions related to sex hormone imbalances, including PCOS, hypothyroidism, testosterone deficiency, estrogen deficiency, and disorders of puberty or thyrotoxicosis.

Test Code
3634
Price
₹2,750
Sample Type
Serum
Result Time
Reports are delivered the same day if the sample is received by 4 pm on Monday or Thursday.
Fasting Required
No
Method
Chemiluminescent Immunoassay
Step 1

Sample Collection

No special preparation required. Inform your doctor about any medications you are taking as they may affect SHBG levels.

Method: Venipuncture

Step 2

Laboratory Analysis

A blood sample will be drawn from a vein in your arm. You may feel a slight pinch during the procedure.

Step 3

Report Delivery

You can resume normal activities immediately. Apply pressure at the puncture site if bleeding occurs.

Timeline: Reports are delivered the same day if the sample is received by 4 pm on Monday or Thursday.

Patient Instructions

1
Before the Test:No special preparation required. Continue your regular diet and medications unless instructed otherwise by your physician.
2
During the Test:You will have a standard blood draw from a vein in the arm. The procedure takes only a few minutes.
3
After the Test:No restrictions after sampling. You may return to work or daily activities immediately.

About This Test

Who Should Get This Test

To assess SHBG levels and help diagnose and monitor conditions related to sex hormone imbalances, including PCOS, hypothyroidism, testosterone deficiency, estrogen deficiency, and disorders of puberty or thyrotoxicosis.

How to Prepare

  • Confirm patient identity
  • Collect 2 mL serum using SST
  • Label the sample correctly
  • Ship refrigerated or frozen as per guidelines

Doctor's Notes

Reviewed by — MBBS, MD (Biochemistry) · Reg. No. 21504

"SHBG measurement provides critical insight into the balance of sex hormones. It is essential for evaluating PCOS, erectile dysfunction, and other disorders. At DNA Labs India, we ensure precise biochemical analysis and clear guidance for patients."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeSerum
Sample Volume2 mL (1 mL min.)
ContainerSST (Serum Separator Tube)
Collection MethodVenipuncture

Sample Stability

Room Temperature: 6 hours
Refrigerated: 1 week
Frozen: 4 weeks
Sample Rejection Criteria:
  • Hemolysed, lipemic or icteric samples
  • Improper labeling
  • Inappropriate storage temperature

Understanding Your Results

Elevated SHBG levels reduce free testosterone and estrogen availability, while low SHBG increases free active hormones. Interpretation should consider age, gender, and clinical context.
📊

High SHBG

May indicate hyperthyroidism, liver disease, anorexia nervosa, estrogen therapy, pregnancy, or anticonvulsant use.

📊

Low SHBG

Seen in PCOS, obesity, hypothyroidism, type 2 diabetes, androgen therapy, and Cushing's syndrome.

⚠️ When to Consult a Doctor:

Consult an endocrinologist if SHBG levels are outside the reference range or if you have persistent symptoms such as hirsutism, infertility, menstrual irregularities, or erectile dysfunction.

Risks & Considerations

  • Minimal risk of bleeding or bruising at puncture site
  • Temporary discomfort
  • Infection at injection site is extremely rare

Interfering Factors

  • Pregnancy
  • Oral contraceptives
  • Anticonvulsant medications
  • Androgens and glucocorticoids
  • Liver disease
  • Obesity
  • Hyperinsulinemia

Frequently Asked Questions

What is SHBG?
SHBG stands for Sex Hormone Binding Globulin, a protein made by the liver that binds to testosterone and estrogen and controls their active free levels in the blood.
Why is the SHBG test done?
It is done to evaluate the cause of symptoms such as low libido, erectile dysfunction, infertility, irregular periods, acne, and hirsutism. It also helps in diagnosing PCOS, thyroid disorders, and other endocrine conditions.
Is fasting required for the SHBG test?
No, the SHBG test does not require fasting. You can eat and drink normally before the test.
What is the cost of the SHBG test at DNA Labs India?
The test costs Rs 2749.5 at DNA Labs India. This includes free home sample collection and an online report.
How is home sample collection done?
After you book online, a trained phlebotomist visits your home at a scheduled time to collect the blood sample. The sample is then transported to the lab under controlled conditions.
When will I get the report?
If your sample is collected before 4 pm on Monday or Thursday, the report is delivered on the same day. Reports are also available via email/WhatsApp.
What sample is needed for the SHBG test?
A 2 mL (1 mL minimum) serum sample is required, collected in an SST (serum separator tube) from a vein.
What can affect SHBG levels?
Pregnancy, oral contraceptives, anticonvulsants, androgens, glucocorticoids, liver disease, obesity, and hyperinsulinemia can alter SHBG levels.
What is a normal SHBG level?
Normal ranges are: adult male: 10-57 nmol/L; adult premenopausal female: 18-144 nmol/L; postmenopausal female: 19-125 nmol/L. Exact ranges may differ by laboratory.
How is SHBG different from total testosterone?
Total testosterone includes both free and bound fractions. SHBG determines the amount of testosterone that is bound. Measuring SHBG along with total testosterone helps calculate free androgen index.
Can medicine affect SHBG test results?
Yes, medications like birth control pills, hormones, and some epilepsy drugs can change SHBG levels. Mention your medication list to your doctor.
Is the SHBG test covered by insurance?
Most health insurance plans in India do not cover routine diagnostic tests unless specifically prescribed and covered under your policy. Check with your insurance provider for details.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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