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DNA Labs India

SGCE Gene DYT11 NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

SGCE Gene DYT11 NGS Genetic Test

Short Name: SGCE DYT11 NGS Test

Also known as: SGCE mutation test, DYT11 genetic test, Myoclonus-dystonia genetic test

SGCE Gene DYT11 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks from sample receipt to report delivery. Free home collection in 300+ cities across India.

Next-Generation SequencingPediatric to Adult🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

The purpose of the SGCE Gene DYT11 NGS Genetic Test is to identify mutations in the SGCE gene for definitive diagnosis of DYT11 dystonia, aiding in personalized treatment, genetic counseling, and management of the disorder.

Test Code
1579
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 weeks from sample receipt to report delivery
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

No specific preparation required, but inform about any medications, recent transfusions, or health conditions. Genetic counseling is recommended.

Method: Venipuncture or FTA card spot

Step 2

Laboratory Analysis

Blood sample is drawn via venipuncture by a trained professional. For FTA card, a finger prick is used. The process is quick and minimally invasive.

Step 3

Report Delivery

Sample is transported to the lab under controlled conditions. Patients should follow up with their doctor for result interpretation.

Timeline: 3 to 4 weeks from sample receipt to report delivery

Patient Instructions

1
Before the Test:Consult with a healthcare provider to discuss symptoms and family history. Genetic counseling is advised to understand test implications.
2
During the Test:The test involves sample collection only; analysis is performed in the lab using NGS technology with no patient involvement.
3
After the Test:Receive results in 3-4 weeks. Follow up with your doctor for diagnosis confirmation and management plan development.

About This Test

Who Should Get This Test

The purpose of the SGCE Gene DYT11 NGS Genetic Test is to identify mutations in the SGCE gene for definitive diagnosis of DYT11 dystonia, aiding in personalized treatment, genetic counseling, and management of the disorder.

How to Prepare

  • Use sterile collection equipment
  • Label samples with patient details accurately
  • Store blood samples at 2-8°C if not processed immediately

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"The SGCE Gene DYT11 NGS Genetic Test is crucial for confirming DYT11 dystonia, enabling personalized treatment and genetic counseling for affected families."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Sample Volume5 mL Blood or as per requirement
ContainerEDTA tube or FTA card
Collection MethodVenipuncture or FTA card spot

Sample Stability

Blood: Stable for 7 days at 2-8°C
Extracted DNA: Stable for years at -20°C
FTA card: Stable at room temperature for months
Sample Rejection Criteria:
  • Hemolyzed or clotted samples
  • Insufficient sample volume
  • Improperly labeled or contaminated samples

Understanding Your Results

Results from the SGCE Gene DYT11 NGS Genetic Test indicate the presence or absence of mutations in the SGCE gene. Positive results confirm DYT11 dystonia, while negative results may necessitate further evaluation for other causes.
Positive for pathogenic mutation: Confirms DYT11 dystonia; refer to neurologist for management
Negative for mutation: SGCE-related dystonia unlikely; consider alternative diagnoses
Variant of uncertain significance: Genetic counseling recommended for further evaluation
Carrier status: May inform family risk and counseling
⚠️ When to Consult a Doctor:

Consult a neurologist or genetic specialist if you experience symptoms like involuntary muscle movements, abnormal postures, or if there is a family history of dystonia, especially in childhood or adolescence.

Limitations

  • ⚠May not detect all mutation types, such as large deletions
  • ⚠Results require clinical correlation and genetic counseling
  • ⚠Variant of uncertain significance may be reported

Risks & Considerations

  • ●Minimal risk from blood draw (bruising, infection)
  • ●Potential psychological impact of results
  • ●Risk of ambiguous results requiring further testing

Interfering Factors

  • ●Sample contamination or degradation
  • ●Prior blood transfusions may affect results
  • ●Technical errors in sequencing

Compare With Similar Tests

TestSGCE Gene DYT11 NGS Genetic TestTOR1A Gene DYT1 Genetic TestGeneral Dystonia Genetic PanelWhole Exome Sequencing
ComparisonSGCE Gene DYT11 NGS Genetic TestTargets DYT1 dystonia, which is more common but involves a different gene; SGCE test is specific for DYT11.Covers multiple dystonia genes, providing broader screening but less depth for SGCE mutations.More comprehensive but costly and time-consuming; NGS test is targeted and efficient for SGCE.

Frequently Asked Questions

What is the SGCE Gene DYT11 NGS Genetic Test?
It is a genetic test that detects mutations in the SGCE gene to diagnose DYT11 dystonia, a rare movement disorder characterized by involuntary muscle contractions and abnormal postures.
What is the cost of the SGCE Gene DYT11 NGS Genetic Test?
The test costs INR 20000 at DNA Labs India, which includes genetic testing, analysis, and interpretation of results.
How is the sample collected for this test?
Sample can be collected via blood draw or using an FTA card. DNA Labs India offers free home sample collection across India for online bookings.
What are the common symptoms of DYT11 dystonia?
Symptoms include involuntary muscle contractions, twisting movements, abnormal postures, tremors, difficulty speaking, and walking problems, often starting in childhood or adolescence.
How accurate is the NGS genetic test for SGCE mutations?
The test uses next-generation sequencing technology with over 99% accuracy for detecting pathogenic mutations in the SGCE gene.
Is fasting required before taking the test?
No, fasting is not required for this genetic test. No special preparation is needed.
How long does it take to receive the test results?
Results are typically available within 3 to 4 weeks from the date of sample collection.
Can children undergo this genetic test?
Yes, the test is suitable for all age groups, including children and adolescents, as DYT11 dystonia often presents early in life.
What does a negative test result mean?
A negative result suggests no mutation in the SGCE gene was detected, but clinical evaluation may still be necessary to rule out other causes of dystonia.
Is genetic counseling recommended before and after the test?
Yes, genetic counseling is highly recommended to understand the test implications, interpret results accurately, and discuss management options.
Does DNA Labs India provide raw data files with the test report?
Yes, DNA Labs India is transparent and provides raw data, FASTQ, and VCF files along with the conclusive clinical report for this test.
How can I book the SGCE Gene DYT11 NGS Genetic Test?
You can book the test online through the DNA Labs India website or by contacting their customer service. Home sample collection is available for online bookings at a discounted price.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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