SLC29A3 Gene Histiocytosis-lymphadenopathy plus syndrome NGS Genetic Test
Short Name: SLC29A3 HLAS NGS Test
Also known as: Histiocytosis-lymphadenopathy plus syndrome, HLAS
SLC29A3 Gene Histiocytosis-lymphadenopathy plus syndrome NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3-4 weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of this test is to identify pathogenic mutations in the SLC29A3 gene to confirm a diagnosis of Histiocytosis-lymphadenopathy plus syndrome (HLAS), guide treatment decisions, and facilitate genetic counseling for affected individuals and their families.
- Test Code
- 4964
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3-4 weeks
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
Clinical history of the patient and a genetic counseling session to draw a pedigree chart of family members affected with HLAS are recommended before testing.
Method: Venipuncture or FTA card
Laboratory Analysis
Standard blood draw procedure using venipuncture or collection of a blood drop on an FTA card. No special preparation is required.
Report Delivery
Apply pressure to the puncture site to prevent bleeding. Store samples as per instructions for stability.
Timeline: 3-4 weeks
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to identify pathogenic mutations in the SLC29A3 gene to confirm a diagnosis of Histiocytosis-lymphadenopathy plus syndrome (HLAS), guide treatment decisions, and facilitate genetic counseling for affected individuals and their families.
How to Prepare
- No fasting required
- Bring valid ID and prescription
- Ensure sample is properly labeled
- For FTA card, follow specific instructions for blood application
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Genetic testing for HLAS is crucial for early diagnosis and management. Consult with a genetic counselor for family planning and treatment options."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted sample
- Insufficient sample volume
- Improperly labeled or contaminated samples
Understanding Your Results
No pathogenic variants detected
Negative for SLC29A3 mutations; HLAS unlikely but clinical correlation is advised.
Pathogenic or likely pathogenic variant detected
Confirms diagnosis of HLAS; genetic counseling and treatment planning recommended.
Variant of uncertain significance (VUS)
Further testing or family studies may be needed; clinical management based on symptoms.
Consult a geneticist, immunologist, or dermatologist if symptoms persist, worsen, or if there is a family history of HLAS. Genetic counseling is advised for all positive results.
Limitations
- ⚠May not detect all types of mutations (e.g., large deletions/duplications)
- ⚠Results require interpretation by a genetic counselor or specialist
- ⚠Does not rule out other genetic or non-genetic causes of symptoms
Risks & Considerations
- ●Minimal risk from blood draw (e.g., bruising, infection)
- ●Psychological impact of genetic results
- ●Potential for uncertain results requiring further testing
Interfering Factors
- ●Sample contamination
- ●Degraded DNA
- ●Hemolyzed blood sample
Compare With Similar Tests
| Test | SLC29A3 Gene Histiocytosis-lymphadenopathy plus syndrome NGS Genetic Test | Whole Exome Sequencing | Targeted Gene Panel for Immunodeficiency | Sanger Sequencing |
|---|---|---|---|---|
| Comparison | SLC29A3 Gene Histiocytosis-lymphadenopathy plus syndrome NGS Genetic Test |
Frequently Asked Questions
What is the SLC29A3 Gene Histiocytosis-lymphadenopathy plus syndrome NGS Genetic Test?
Who should get this test?
What is the cost of the test in India?
How is the sample collected?
Is fasting required before the test?
How long does it take to get results?
What do the results mean?
Is genetic counseling recommended?
What files are provided with the report?
Can this test be done for children?
Is the test covered by insurance?
What are the risks of the test?
Related Tests
Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
Book Your Test
Enter your details and we'll connect you within 15 minutes.