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DNA Labs India

SLE (Systemic Lupus Erythematosus) Panel Test

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SLE (Systemic Lupus Erythematosus) Panel Test

Short Name: SLE Panel Test

Also known as: SLE Panel, Lupus Profile, Systemic Lupus Erythematosus Antibody Panel

SLE (Systemic Lupus Erythematosus) Panel Test test available at DNA Labs India for ₹6,000. Uses EIA on Serum samples. Results in Reports are generally delivered the same day if the sample reaches the laboratory by 9 am on Tuesday or Friday. For other collection times, reports will be available on the next scheduled processing day.. Free home collection in 300+ cities across India.

Serology / Autoantibody Panel🏠 Home Collection

Overview

The purpose of the SLE Panel is to identify autoantibodies commonly associated with systemic lupus erythematosus. The test helps doctors evaluate a patient with suspected lupus, supports the clinical diagnosis, and provides information about antiphospholipid antibody status, which may coexist in SLE. It is not a standalone diagnostic test and should be interpreted along with clinical signs and symptoms.

Test Code
3649
Price
₹6,000
Sample Type
Serum
Result Time
Reports are generally delivered the same day if the sample reaches the laboratory by 9 am on Tuesday or Friday. For other collection times, reports will be available on the next scheduled processing day.
Fasting Required
No
Method
EIA
Step 1

Sample Collection

No special preparation is required. Inform your doctor about any current medications, especially steroids or immunosuppressants.

Method: Venipuncture

Step 2

Laboratory Analysis

A blood sample is collected from a vein in your arm. The procedure takes only a few minutes and involves a brief needle prick.

Step 3

Report Delivery

No specific precautions are needed. You can resume normal activities immediately after sample collection.

Timeline: Reports are generally delivered the same day if the sample reaches the laboratory by 9 am on Tuesday or Friday. For other collection times, reports will be available on the next scheduled processing day.

Patient Instructions

1
Before the Test:No fasting required. Tell your doctor about all medicines you are taking before the blood sample is drawn.
2
During the Test:The phlebotomist will clean the area, apply a tourniquet, and collect blood from a vein. You may feel a brief sting.
3
After the Test:You can leave immediately after the test. Keep pressure on the puncture site for a minute or two to prevent bruising.

About This Test

Who Should Get This Test

The purpose of the SLE Panel is to identify autoantibodies commonly associated with systemic lupus erythematosus. The test helps doctors evaluate a patient with suspected lupus, supports the clinical diagnosis, and provides information about antiphospholipid antibody status, which may coexist in SLE. It is not a standalone diagnostic test and should be interpreted along with clinical signs and symptoms.

How to Prepare

  • No fasting required
  • Inform the phlebotomist if you have a history of fainting during blood collection
  • Do not stop prescribed medication without consulting your doctor

Doctor's Notes

"A positive serology result should never be interpreted alone. Autoantibodies can appear years before symptoms, so clinical correlation with a rheumatologist is essential."

Test Parameters & Specifications

Sample TypeSerum
Sample Volume4 mL (2 mL min.)
Container1 SST (Serum Separator Tube)
Collection MethodVenipuncture

Sample Stability

Room temperature (18-25°C)6 hours
Refrigerated (2-8°C)48 hours
Frozen (-20°C)2 weeks
Sample Rejection Criteria:
  • Hemolyzed serum
  • Clotted sample
  • Improperly labelled collection tube
  • Sample stored at room temperature for more than 6 hours
  • Use of a non-SST or wrong anticoagulant tube

Understanding Your Results

The results of the SLE Panel should be interpreted by a qualified physician, usually a rheumatologist, using the patient's clinical history and physical examination findings.
📊

Strongly supports the diagnosis of systemic lupus erythematosus.

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May be seen in healthy people or in other autoimmune conditions; requires clinical correlation.

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Associated with active SLE, particularly with kidney involvement.

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Highly specific for SLE even if other antibodies are negative.

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Suggests possible antiphospholipid syndrome; repeat testing after 12 weeks is often needed for confirmation.

⚠️ When to Consult a Doctor:

Consult a rheumatologist if you have persistent facial rash, joint swelling, unexplained fever, severe fatigue, hair loss, mouth ulcers, chest pain, or if the SLE panel result is positive or borderline.

Limitations

  • A negative result cannot completely exclude SLE
  • Autoantibodies may be present in people without clinical disease
  • Anti-Sm is specific but not sensitive; absence does not rule out SLE
  • Anti-dsDNA may be low or absent in some SLE patients or during remission
  • This panel does not diagnose all connective tissue or autoimmune diseases

Risks & Considerations

  • Bruising at the venipuncture site
  • Dizziness or light-headedness
  • Local pain or swelling
  • Infection at the puncture site (very rare)

Interfering Factors

  • Immunosuppressive therapy such as steroids may reduce autoantibody levels
  • Intercurrent infections or recent vaccination may cause transiently positive ANA or phospholipid antibodies
  • Certain drugs such as hydralazine, procainamide, and isoniazid can cause drug-induced lupus and positive ANA
  • Hemolyzed or lipemic serum samples may interfere with EIA testing

Compare With Similar Tests

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Frequently Asked Questions

What is the SLE (Systemic Lupus Erythematosus) Panel test?
The SLE Panel is a group of blood tests used to detect autoantibodies commonly associated with systemic lupus erythematosus, including ANA, anti-dsDNA, anti-Sm, and phospholipid antibodies. It helps support the diagnosis and guide further clinical evaluation.
What autoantibodies are included in the SLE Panel test?
The panel includes Antinuclear Antibody (ANA), Anti-dsDNA Antibody, Anti-Sm Antibody, Phospholipid Antibody IgG, and Phospholipid Antibody IgM.
What is the cost of the SLE Panel test at DNA Labs India?
The cost is Rs 6000, which includes home sample collection in participating cities across India.
Is fasting required before the SLE Panel test?
No, no special preparation is required. You can eat and drink normally before the blood sample is collected.
How is the blood sample collected for the SLE Panel?
A trained phlebotomist collects about 4 mL of blood from a vein in your arm into a serum separator tube. The procedure is quick and routine.
How long will the SLE Panel report take?
If the sample reaches the laboratory by 9 am on Tuesday or Friday, the report is generally delivered on the same day.
Is home sample collection available for the SLE Panel test?
Yes, DNA Labs India offers free home sample collection for the SLE Panel test in many cities across India.
Can the SLE Panel test alone confirm lupus?
No. The test provides supportive evidence, but the diagnosis of SLE also requires clinical features. A rheumatologist interprets the results along with medical history and examination findings.
What is the reference range for the SLE Panel test?
The autoantibodies included in this panel are generally reported as negative in apparently healthy individuals. Reference ranges can vary slightly between laboratories.
What does a positive ANA mean in the SLE Panel?
A positive ANA may be seen in SLE and other autoimmune disorders, or sometimes in healthy people. More specific antibodies such as anti-dsDNA and anti-Sm help clarify the risk.
Who usually orders the SLE Panel test?
The test is typically advised by a rheumatologist or physician when a person has symptoms suggesting systemic lupus erythematosus or another autoimmune connective tissue disease.
Which cities does DNA Labs India cover for home collection?
Home sample collection is available in major cities including Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Pune, Jaipur, Lucknow, and many other locations across India.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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