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DNA Labs India

SRPX2 Gene Rolandic epilepsy, mental retardation, and speech dyspraxia NGS Genetic Test

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SRPX2 Gene Rolandic epilepsy, mental retardation, and speech dyspraxia NGS Genetic Test

Short Name: SRPX2 Gene NGS Test

Also known as: SRPX2 Genetic Test, SRPX2 Mutation Analysis, Rolandic Epilepsy Genetic Test

SRPX2 Gene Rolandic epilepsy, mental retardation, and speech dyspraxia NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3-4 weeks from sample receipt. Free home collection in 300+ cities across India.

NeurologyAll Ages🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

To identify mutations in the SRPX2 gene that cause Rolandic epilepsy, mental retardation, and speech dyspraxia, aiding in diagnosis, treatment planning, and genetic counseling.

Test Code
1799
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3-4 weeks from sample receipt
Fasting Required
No
Method
Next Generation Sequencing (NGS)
Step 1

Sample Collection

Genetic counseling session to discuss family history and draw a pedigree chart.

Method: Venipuncture or FTA Card Blot

Step 2

Laboratory Analysis

Blood sample collected via venipuncture or one drop on FTA card.

Step 3

Report Delivery

Sample sent to lab for analysis. Results in 3-4 weeks.

Timeline: 3-4 weeks from sample receipt

Patient Instructions

1
Before the Test:Consult a genetic counselor for pre-test counseling.
2
During the Test:Sample collection procedure as per instructions.
3
After the Test:Await results and schedule post-test counseling.

About This Test

Who Should Get This Test

To identify mutations in the SRPX2 gene that cause Rolandic epilepsy, mental retardation, and speech dyspraxia, aiding in diagnosis, treatment planning, and genetic counseling.

How to Prepare

  • Use sterile technique
  • Label samples properly
  • Store at ambient temperature

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Genetic testing for SRPX2 mutations is crucial for early diagnosis and personalized management of neurological disorders in affected individuals."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Sample VolumeAs per sample type
ContainerEDTA Tube or FTA Card
Collection MethodVenipuncture or FTA Card Blot

Sample Stability

Blood: 2-8°C for 24 hours
FTA card: Room temperature for extended period
Sample Rejection Criteria:
  • Hemolyzed or clotted samples
  • Unlabeled samples
  • Insufficient volume

Understanding Your Results

Results indicate whether mutations in the SRPX2 gene are detected. Positive results suggest a genetic cause for symptoms, while negative results may require further testing.
Positive: Pathogenic mutation found, associated with disease risk
Negative: No mutations detected, but does not rule out other genetic causes
Variant of uncertain significance: Requires further evaluation
⚠️ When to Consult a Doctor:

If you experience symptoms of Rolandic epilepsy, mental retardation, or speech dyspraxia, or have a family history of these conditions.

Limitations

  • ⚠May not detect all types of mutations, such as large deletions or duplications
  • ⚠Results should be correlated with clinical findings
  • ⚠Genetic counseling is advised for interpretation

Risks & Considerations

  • ●Minimal risk from blood draw
  • ●Psychological impact of genetic results

Interfering Factors

  • ●Sample contamination
  • ●Degraded DNA
  • ●Insufficient sample volume

Frequently Asked Questions

What is the SRPX2 Gene NGS Genetic Test?
It is a Next Generation Sequencing test to detect mutations in the SRPX2 gene, which are linked to Rolandic epilepsy, mental retardation, and speech dyspraxia.
Who should undergo this test?
Individuals with symptoms of Rolandic epilepsy, mental retardation, speech dyspraxia, or a family history of these conditions should consider testing.
How is the test performed?
A blood sample or extracted DNA is collected and analyzed using NGS technology to identify SRPX2 gene mutations.
What is the cost of the test?
The test costs INR 20,000 at DNA Labs India, with free home sample collection available across India.
How long does it take to get results?
Results are typically available within 3-4 weeks from sample receipt.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection for online bookings across numerous Indian cities.
What are the symptoms of SRPX2 gene mutation?
Symptoms include seizures, cognitive impairment, speech difficulties, abnormal muscle movements, and delayed language development.
Can this test detect all mutations?
While NGS is highly accurate, it may not detect all mutation types; correlation with clinical findings is recommended.
Is genetic counseling included?
Yes, a genetic counseling session is recommended before and after the test, and is included in the price.
What should I do if the test is positive?
Consult a healthcare provider or genetic counselor for management options, which may include treatment and family planning.
Is the test covered by insurance?
Coverage depends on your insurance plan; check with your provider. Government schemes like PMJAY may not cover it.
How do I book the test?
You can book online through DNA Labs India's website or contact them for home sample collection.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

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Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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