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STIM1 Gene Immunodeficiency type 10 NGS Genetic Test

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STIM1 Gene Immunodeficiency type 10 NGS Genetic Test

Short Name: STIM1 Immunodeficiency Type 10 Test

Also known as: STIM1 Immunodeficiency Type 10, Immunodeficiency Type 10

STIM1 Gene Immunodeficiency type 10 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.

Next-Generation Sequencing (NGS)🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Pasupathy Arumugam

Dr Pasupathy Arumugam

Consultant Pathologist · Reg: 21521

Last reviewed: September 7, 2026

Overview

To diagnose STIM1 gene immunodeficiency type 10 by detecting pathogenic variants in the STIM1 gene using NGS technology, enabling accurate clinical management and genetic counseling.

Test Code
5000
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 weeks
Fasting Required
No
Method
Next-Generation Sequencing (NGS)
Step 1

Sample Collection

Clinical history review and genetic counseling session to draw a pedigree chart of affected family members.

Method: Venipuncture

Step 2

Laboratory Analysis

Blood sample collected via venipuncture or use of FTA card for one drop of blood.

Step 3

Report Delivery

Sample transported to laboratory under appropriate conditions for DNA extraction and analysis.

Timeline: 3 to 4 weeks

Patient Instructions

1
Before the Test:Genetic counseling session to discuss test implications, family history, and obtain informed consent.
2
During the Test:Blood sample collection and laboratory analysis using NGS technology.
3
After the Test:Report generation, delivery via online portal, email, or WhatsApp, followed by consultation to discuss results.

About This Test

Who Should Get This Test

To diagnose STIM1 gene immunodeficiency type 10 by detecting pathogenic variants in the STIM1 gene using NGS technology, enabling accurate clinical management and genetic counseling.

How to Prepare

  • Fasting is not required
  • Avoid hemolyzed or contaminated samples
  • Ensure proper labeling of samples

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"Genetic testing is crucial for accurate diagnosis and management of immunodeficiency disorders, enabling personalized treatment plans."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Sample Volume5-10 ml blood
ContainerEDTA tube or FTA card
Collection MethodVenipuncture

Sample Stability

Blood: Store at 2-8°C for up to 48 hours
Extracted DNA: Stable at -20°C for long-term storage
Sample Rejection Criteria:
  • Insufficient sample volume
  • Contaminated or degraded samples
  • Improperly labeled specimens

Understanding Your Results

Results indicate the presence or absence of pathogenic variants in the STIM1 gene, which are associated with immunodeficiency type 10.
Positive result: Pathogenic variant detected, confirming diagnosis of STIM1 gene immunodeficiency type 10
Negative result: No pathogenic variants detected; consider other genetic or immunological tests
Variant of uncertain significance (VUS): Further testing or family studies may be required for clarification
⚠️ When to Consult a Doctor:

If symptoms such as recurrent infections, chronic diarrhea, or growth delays persist, or if there is a family history of immunodeficiency, consult a healthcare provider for evaluation and possible genetic testing.

Limitations

  • ⚠May not detect all genetic variants
  • ⚠Requires interpretation by a genetic specialist
  • ⚠Results may have psychological implications

Risks & Considerations

  • ●Minimal risk from blood draw, such as bruising or infection
  • ●Potential psychological impact of genetic results
  • ●Risk of incidental findings unrelated to the test

Interfering Factors

  • ●Sample contamination
  • ●Degraded DNA
  • ●Hemolyzed blood samples

Compare With Similar Tests

TestSTIM1 Gene Immunodeficiency type 10 NGS Genetic TestWhole Exome SequencingSanger SequencingImmunoglobulin Level Test
ComparisonSTIM1 Gene Immunodeficiency type 10 NGS Genetic Test

Frequently Asked Questions

What is STIM1 Gene Immunodeficiency Type 10?
It is a rare genetic disorder caused by mutations in the STIM1 gene, leading to impaired immune function and increased susceptibility to infections.
What are the common symptoms of this disorder?
Symptoms include recurrent respiratory, ear, and sinus infections, chronic diarrhea, failure to thrive, and delayed growth and development.
How is the STIM1 Gene Immunodeficiency Type 10 NGS Genetic Test performed?
The test uses next-generation sequencing (NGS) to analyze the STIM1 gene from a blood or DNA sample, detecting pathogenic variants.
What is the cost of the test?
The test costs INR 20000, which includes sample collection, analysis, and report generation.
Is home sample collection available?
Yes, free home sample collection is available for online bookings across many cities in India.
How long does it take to get the test results?
Results are typically available within 3 to 4 weeks after sample collection.
What does a positive test result mean?
A positive result indicates the presence of a pathogenic variant in the STIM1 gene, confirming a diagnosis of immunodeficiency type 10.
What if the test result is negative?
A negative result means no pathogenic variants were detected; further clinical evaluation or other tests may be needed if symptoms persist.
Are there any risks associated with the test?
Risks are minimal, primarily related to blood draw, such as bruising. Genetic results may have psychological implications.
Is genetic counseling necessary before and after the test?
Yes, genetic counseling is recommended to understand the test's implications, interpret results, and plan management.
Can this test be used for prenatal diagnosis?
This test is typically for postnatal diagnosis; prenatal testing may require specialized procedures and genetic counseling.
How accurate is the NGS genetic test for STIM1 immunodeficiency?
NGS is highly accurate for detecting known pathogenic variants, but accuracy depends on sample quality and variant interpretation.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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