TANC2 Gene TANC2 related brain disorders NGS Genetic Test
Short Name: TANC2 NGS Test
Also known as: TANC2 gene sequencing, TANC2-related disorder panel, TANC2 NGS analysis
TANC2 Gene TANC2 related brain disorders NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in Reports are typically available within 3 to 4 weeks after sample receipt.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The purpose of this test is to detect mutations in the TANC2 gene that are associated with neurodevelopmental disorders such as autism, intellectual disability, and developmental delay. Early diagnosis helps in planning therapeutic interventions, genetic counseling, and family planning decisions.
- Test Code
- 5947
- CPT Code
- 81407
- ICD Code
- F84.9, F70.9, F80.9, F88
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- Reports are typically available within 3 to 4 weeks after sample receipt.
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
No fasting required. Inform your doctor about any medications or supplements. A genetic counseling session is recommended before the test.
Method: Venipuncture or Finger prick
Laboratory Analysis
Blood sample will be collected by a trained phlebotomist. For FTA card, a simple finger prick is sufficient.
Report Delivery
No special precautions. You can resume normal activities immediately.
Timeline: Reports are typically available within 3 to 4 weeks after sample receipt.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to detect mutations in the TANC2 gene that are associated with neurodevelopmental disorders such as autism, intellectual disability, and developmental delay. Early diagnosis helps in planning therapeutic interventions, genetic counseling, and family planning decisions.
How to Prepare
- Blood sample should be collected in an EDTA tube.
- If using FTA card, ensure the blood spot is completely dried before packaging.
- Label the sample with patient name, date of birth, and collection date.
- Transport the sample to the lab within 24 hours at ambient temperature.
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"TANC2 mutations are rare but significant causes of neurodevelopmental disorders. Early genetic diagnosis enables tailored management and family counseling."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted blood sample
- Insufficient sample volume
- Incorrect labeling
- Sample received after prolonged transit time (>72 hours)
Understanding Your Results
Positive (Pathogenic variant)
Confirms the diagnosis of TANC2-related disorder. Genetic counseling is recommended for the family.
Action: Discuss management options and family planning.
Negative (No variant)
No disease-causing variant found in TANC2. Other genetic or non-genetic causes should be considered.
Action: Further evaluation by a specialist may be needed.
Variant of Uncertain Significance (VUS)
A variant was found but its clinical significance is unknown. Additional testing or family studies may help.
Action: Consult with a geneticist for further analysis.
Consult a doctor if you or your child experience developmental delays, intellectual disability, speech difficulties, or behavioral issues. Early diagnosis can lead to better outcomes.
Limitations
- ⚠This test only analyzes the TANC2 gene; other genetic causes may not be detected.
- ⚠Variant of uncertain significance (VUS) may be reported; further testing may be needed.
- ⚠NGS may not detect large deletions/duplications or deep intronic variants.
- ⚠Test does not assess non-genetic causes of symptoms.
Risks & Considerations
- ●Minimal risk of bruising or infection at the blood draw site
- ●Psychological impact of genetic results
- ●Possibility of finding variants of uncertain significance
Interfering Factors
- ●Contaminated or degraded DNA sample
- ●Insufficient sample quantity
- ●Presence of maternal cell contamination (if blood from cord)
- ●Recent blood transfusion (within 2 weeks)
Compare With Similar Tests
| Test | TANC2 Gene TANC2 related brain disorders NGS Genetic Test | Whole Exome Sequencing (WES) | Chromosomal Microarray (CMA) |
|---|---|---|---|
| Comparison | TANC2 Gene TANC2 related brain disorders NGS Genetic Test |
Frequently Asked Questions
What is the TANC2 gene?
What conditions are associated with TANC2 mutations?
How is the TANC2 NGS test performed?
What is the cost of the TANC2 NGS test at DNA Labs India?
How long does it take to get the results?
Is fasting required before the test?
Can the test be done on children?
Will I receive raw data files?
What is the sample type for this test?
Is genetic counseling included?
Are there any risks associated with the test?
Can this test detect all genetic causes of brain disorders?
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