Testosterone & Sex Hormone Binding Globulin Test
Short Name: Testosterone & SHBG
Also known as: Testosterone & SHBG Test, Total Testosterone with SHBG, Androgen Profile with SHBG
Testosterone & Sex Hormone Binding Globulin Test test available at DNA Labs India for ₹4,680. Uses Radioimmunoassay, CLIA on Serum samples. Results in Reports are usually released on the same day if the sample reaches the laboratory by 9 am on Monday or Thursday.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Ramarao Paidisetty
Consultant Biochemist · Reg: 21504
Last reviewed: September 7, 2026
Overview
The purpose of this test is to measure testosterone and SHBG levels in serum. It helps diagnose low testosterone states, monitor testosterone replacement therapy, and investigate SHBG abnormalities. It is also useful in the evaluation of female hyperandrogenism, hirsutism, menstrual disturbances and infertility.
- Test Code
- 3686
- Price
- ₹4,680
- Sample Type
- Serum
- Result Time
- Reports are usually released on the same day if the sample reaches the laboratory by 9 am on Monday or Thursday.
- Fasting Required
- No
- Method
- Radioimmunoassay, CLIA
Sample Collection
No special preparation is required. Inform your doctor about any current medicines, supplements or existing medical conditions.
Method: Venipuncture
Laboratory Analysis
A trained phlebotomist will collect about 3 mL of blood from a vein in your arm using a Serum Separator Tube (SST). The process is quick and minimal.
Report Delivery
You may leave immediately after sample collection and continue daily activities. The puncture site may be slightly tender for a short period.
Timeline: Reports are usually released on the same day if the sample reaches the laboratory by 9 am on Monday or Thursday.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to measure testosterone and SHBG levels in serum. It helps diagnose low testosterone states, monitor testosterone replacement therapy, and investigate SHBG abnormalities. It is also useful in the evaluation of female hyperandrogenism, hirsutism, menstrual disturbances and infertility.
How to Prepare
- Specify age and sex on the test request form.
- Use Serum Separator Tube (SST) for sample collection.
- Ship the sample refrigerated or frozen after collection.
- No special preparation or fasting is required.
Doctor's Notes
Reviewed by Dr Ramarao Paidisetty — MBBS, MD (Biochemistry) · Reg. No. 21504
"In my practice, this combination is especially helpful when total testosterone appears normal but the patient has symptoms of androgen deficiency, because SHBG can skew the free testosterone available to tissues."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Specimen not labeled with age and sex
- Hemolyzed or lipemic sample
- Sample received without matching request form
- Sample stored at room temperature beyond the acceptable period
Understanding Your Results
Low total testosterone
High SHBG
Low SHBG
High total testosterone / free testosterone in women
If you are having persistent symptoms of low testosterone, metabolic changes, sexual dysfunction, or unusual hair growth, please consult an endocrinologist or urologist. Do not start any hormone treatment based only on an online report.
Limitations
- ⚠Reference ranges vary between laboratories and assay methods.
- ⚠A single testosterone measurement may not reflect the average level due to biological variation.
- ⚠Calculated free testosterone depends on albumin concentration and may not be accurate in all clinical settings.
- ⚠Results should always be interpreted with clinical history and physical examination.
Risks & Considerations
- ●Mild pain or soreness at the needle site
- ●Small bruising
- ●Dizziness or lightheadedness during or after blood draw
- ●Very rare infection or prolonged bleeding
Interfering Factors
- ●Testosterone levels have diurnal variation; morning sampling is usually preferred.
- ●Age and sex affect reference values and interpretation.
- ●Obesity, insulin resistance, liver disease and thyroid disease can alter SHBG levels.
- ●Medications such as estrogens, androgens, glucocorticoids, anticonvulsants and oral contraceptives can affect SHBG and testosterone.
- ●Pregnancy can increase SHBG levels in women.
Compare With Similar Tests
| Test | Testosterone & Sex Hormone Binding Globulin Test | |||
|---|---|---|---|---|
| Comparison | Testosterone & Sex Hormone Binding Globulin Test |
Frequently Asked Questions
What is the Testosterone & Sex Hormone Binding Globulin Test?
Why is this test ordered?
Do I need fasting for this test?
How is the sample collected?
What is the cost of the Testosterone & SHBG Test in India?
Is home sample collection available?
When will I get the report?
Does the test measure free testosterone?
What are the symptoms of low testosterone?
What can affect SHBG levels?
Is this test covered by insurance?
What should I do if my results are abnormal?
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