TFG Gene Hereditary motor and sensory neuropathy, Okinawa type NGS Genetic Test
Short Name: TFG Gene HMSN Okinawa NGS
Also known as: TFG Neuropathy, HMSN Okinawa type, Hereditary Motor and Sensory Neuropathy with TFG mutation
TFG Gene Hereditary motor and sensory neuropathy, Okinawa type NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Whole blood, Extracted DNA, or one drop blood on FTA Card samples. Results in Reports are released within 3 to 4 weeks from the date of sample receipt at the laboratory.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
To detect pathogenic variants in the TFG gene associated with Hereditary Motor and Sensory Neuropathy, Okinawa type, thereby confirming the clinical diagnosis and enabling appropriate genetic counseling.
- Test Code
- 4127
- ICD Code
- G60.0
- Price
- ₹20,000
- Sample Type
- Whole blood, Extracted DNA, or one drop blood on FTA Card
- Result Time
- Reports are released within 3 to 4 weeks from the date of sample receipt at the laboratory.
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
No fasting is required. Please provide your clinical history, nerve conduction study/EMG reports, and family pedigree if available.
Method: Peripheral blood draw or FTA card spot
Laboratory Analysis
Sample is collected by a trained phlebotomist using sterile techniques. For FTA card, a single drop of blood is applied to the card.
Report Delivery
For FTA card, allow the card to air-dry before placing it in the protective envelope. For blood samples, ensure the tube is labeled and kept at room temperature.
Timeline: Reports are released within 3 to 4 weeks from the date of sample receipt at the laboratory.
Patient Instructions
About This Test
Who Should Get This Test
To detect pathogenic variants in the TFG gene associated with Hereditary Motor and Sensory Neuropathy, Okinawa type, thereby confirming the clinical diagnosis and enabling appropriate genetic counseling.
How to Prepare
- Whole blood in EDTA (purple top) tube - 2 ml preferred
- Extracted DNA - 5 μg in sterile screw-cap tube
- FTA card - one blood spot applied to FTA card, dried naturally
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Clinical correlation with physical examination and electrophysiological studies is essential when interpreting genetic results for hereditary neuropathies."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted blood sample
- Insufficient quantity of blood or DNA
- Improperly labeled or misidentified sample
- FTA card without visible dried blood spot
Understanding Your Results
Pathogenic variant detected
Confirms the diagnosis of TFG gene-related Hereditary Motor and Sensory Neuropathy, Okinawa type.
Variant of uncertain significance (VUS) identified
Clinical significance is currently unclear; additional family studies and segregation analysis may be recommended.
No pathogenic variant detected
Does not confirm the diagnosis; other genetic or acquired causes of HMSN should be considered.
If you or a family member has progressive muscle weakness, sensory loss, or a known family history of HMSN, consult a neurologist or clinical geneticist for evaluation and genetic testing.
Limitations
- ⚠NGS may not detect large deletions/duplications, deep intronic variants, or trinucleotide repeat expansions in the TFG gene
- ⚠Variant of uncertain significance may require additional family studies for reclassification
- ⚠This test is diagnostic for TFG gene-associated HMSN only; negative results do not exclude other genetic causes of HMSN
Risks & Considerations
- ●Minimal risk of bruising or bleeding at the blood draw site
- ●Minor discomfort during sample collection
- ●FTA card collection is virtually painless
Interfering Factors
- ●Recent allogeneic bone marrow transplant may cause blood chimerism affecting DNA analysis
- ●Contamination or degradation of extracted DNA
- ●Low-quality FTA card sample with insufficient blood
Frequently Asked Questions
What is TFG gene HMSN Okinawa type?
Who should consider this NGS genetic test?
What samples are accepted for this test?
Is fasting required for this test?
What is the turnaround time for results?
What is the cost of the TFG gene HMSN NGS test in India?
Can this test detect all types of HMSN?
How is the test performed?
Will this test give a definitive diagnosis?
Do you provide genetic counseling with the test?
Why should I ask for raw data, FASTQ, and VCF files?
Is home sample collection available for this test?
Related Tests
Angelman Syndrome Test
₹10,000Duchenne / Becker Muscular Dystrophy (DMD / BMD) Gene Mutation Test
₹14,000Episodic Ataxia Type 1 Hotspot Test
₹11,500Episodic Ataxia Comprehensive Profile Hotspot Test
₹16,000Megalencephalic Leukoencephalopathy with Subcortical Cysts Van Der Knaap and Nalband MLC Gene Hotspot Mutation Test
₹7,500Analyzer 18 SMA 18 Test Panel
₹1,755Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
Book Your Test
Enter your details and we'll connect you within 15 minutes.