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TFG Gene SPG57 NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

TFG Gene SPG57 NGS Genetic Test

Short Name: TFG Gene SPG57 Test

Also known as: TFG Gene Mutation Test, Hereditary Spastic Paraplegia Type 57 Test

TFG Gene SPG57 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses NGS Technology on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in Reports delivered in 3 to 4 weeks via online portal, email, or WhatsApp.. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Pasupathy Arumugam

Dr Pasupathy Arumugam

Consultant Pathologist · Reg: 21521

Last reviewed: September 7, 2026

Overview

To identify pathogenic mutations in the TFG gene for the diagnosis of Hereditary Spastic Paraplegia (SPG57), aiding in clinical management and genetic counseling.

Test Code
1818
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
Reports delivered in 3 to 4 weeks via online portal, email, or WhatsApp.
Fasting Required
No
Method
NGS Technology
Step 1

Sample Collection

Genetic counseling session to draw a pedigree chart and obtain clinical history of the patient.

Method: Blood draw or FTA card collection

Step 2

Laboratory Analysis

Blood sample collected via venipuncture or FTA card method; procedure is minimally invasive.

Step 3

Report Delivery

Sample is processed and analyzed in the lab; results are reviewed by genetic experts.

Timeline: Reports delivered in 3 to 4 weeks via online portal, email, or WhatsApp.

Patient Instructions

1
Before the Test:Schedule a genetic counseling session and provide clinical history.
2
During the Test:Blood sample collection takes about 10-15 minutes.
3
After the Test:Wait for 3-4 weeks for results; follow-up with doctor for interpretation.

About This Test

Who Should Get This Test

To identify pathogenic mutations in the TFG gene for the diagnosis of Hereditary Spastic Paraplegia (SPG57), aiding in clinical management and genetic counseling.

How to Prepare

  • Provide detailed clinical and family history
  • Ensure proper sample labeling
  • Use sterile collection kits

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"Genetic testing for SPG57 is crucial for accurate diagnosis, family planning, and management of hereditary spastic paraplegia. Early detection can guide therapeutic strategies and genetic counseling."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Collection MethodBlood draw or FTA card collection

Sample Stability

Blood at room temperature
FTA card
Sample Rejection Criteria:
  • Hemolyzed or insufficient sample
  • Incorrect sample type or container

Understanding Your Results

Results indicate whether pathogenic variants in the TFG gene are detected, which can confirm Hereditary Spastic Paraplegia (SPG57).
📊

Pathogenic variant detected

Confirms diagnosis of SPG57; genetic counseling recommended.

📊

No pathogenic variant detected

SPG57 unlikely; consider other genetic or non-genetic causes.

📊

Variant of uncertain significance

Further evaluation and family studies may be needed.

⚠️ When to Consult a Doctor:

If experiencing symptoms of Hereditary Spastic Paraplegia such as progressive leg weakness, stiffness, or balance issues, or if there is a family history of the condition.

Limitations

  • ⚠May not detect all variants in the TFG gene
  • ⚠Results should be correlated with clinical findings

Risks & Considerations

  • ●Minimal risk from blood draw, such as bruising or discomfort

Interfering Factors

  • ●Poor sample quality
  • ●Contamination during collection

Compare With Similar Tests

TestTFG Gene SPG57 NGS Genetic TestWhole Exome SequencingSPG Gene Panel
ComparisonTFG Gene SPG57 NGS Genetic Test

Frequently Asked Questions

What is the TFG Gene SPG57 NGS Genetic Test?
It is a diagnostic test that uses NGS technology to identify mutations in the TFG gene for Hereditary Spastic Paraplegia Type 57.
Who should consider this test?
Individuals with symptoms like leg stiffness, weakness, or balance issues, or those with a family history of hereditary spastic paraplegia.
What are the symptoms of Hereditary Spastic Paraplegia?
Symptoms include difficulty walking, leg stiffness, weakness, numbness, balance problems, and spasticity.
How is the test performed?
A blood sample or extracted DNA is analyzed using NGS technology to detect TFG gene mutations.
What is the cost of the test?
The test costs INR 20,000, with free home sample collection available across India.
Is the test covered by insurance?
Typically, this test is not covered by insurance, and payment is out-of-pocket.
How long does it take to get results?
Results are usually available within 3 to 4 weeks after sample collection.
What sample type is required?
Blood, extracted DNA, or one drop of blood on an FTA card can be used.
Is fasting required for the test?
No, fasting is not required for this genetic test.
Can the test detect all mutations in the TFG gene?
The test targets known pathogenic variants but may not detect all possible mutations.
How accurate is the test?
NGS technology provides high accuracy, but results should be correlated with clinical assessment.
What should I do after receiving results?
Consult a genetic counselor or neurologist for interpretation and next steps, such as management or family testing.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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