TGIF1 Gene Holoprosencephaly type 4 NGS Genetic Test
TGIF1 Gene Holoprosencephaly type 4 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
To diagnose mutations in the TGIF1 gene associated with holoprosencephaly type 4, aiding in clinical management and genetic counseling.
- Test Code
- 5777
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 Weeks
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
Genetic counseling recommended prior to testing.
Laboratory Analysis
Blood sample collected via venipuncture or alternative methods as specified.
Report Delivery
Sample processed for NGS analysis; report delivered in 3-4 weeks.
Timeline: 3 to 4 Weeks
Patient Instructions
About This Test
Who Should Get This Test
To diagnose mutations in the TGIF1 gene associated with holoprosencephaly type 4, aiding in clinical management and genetic counseling.
How to Prepare
- Ensure proper sample labeling
- Use sterile collection tubes
- Follow home collection guidelines if applicable
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"Early genetic testing for TGIF1 mutations can guide management and improve outcomes for children with holoprosencephaly."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
- Hemolyzed sample
- Insufficient sample volume
- Improper labeling
Understanding Your Results
Positive
Pathogenic mutation detected; confirms genetic basis for holoprosencephaly type 4.
Negative
No pathogenic variants detected; does not rule out other genetic causes.
VUS
Variant of uncertain significance; further testing or family studies may be needed.
Consult a genetic specialist or pediatric neurologist upon receiving results for comprehensive management.
Limitations
- ⚠May not detect all genetic variants
- ⚠Requires genetic counseling for interpretation
- ⚠Results should be correlated with clinical findings
Risks & Considerations
- ●Minimal risk from blood draw
- ●Potential for uncertain results requiring further evaluation
Frequently Asked Questions
What is the TGIF1 Gene Holoprosencephaly type 4 NGS Genetic Test?
What is the cost of the test?
What are the symptoms of Holoprosencephaly type 4?
How is the test performed?
What sample is required?
How long does it take to get results?
Is home collection available?
What does a positive result mean?
What are the risks of the test?
Can the test be used for prenatal diagnosis?
Is genetic counseling recommended?
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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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