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TLR3 Gene Herpes simplex encephalitis type 2, susceptibility to NGS Genetic Test

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TLR3 Gene Herpes simplex encephalitis type 2, susceptibility to NGS Genetic Test

Short Name: TLR3 Gene HSE-2 Susceptibility Test

Also known as: TLR3 Gene HSE-2 Susceptibility Test, Herpes Simplex Encephalitis Type 2 Genetic Test

TLR3 Gene Herpes simplex encephalitis type 2, susceptibility to NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood, Extracted DNA, or FTA Card samples. Results in 3 to 4 weeks.. Free home collection in 300+ cities across India.

Next-Generation Sequencing Genetic Test🏠 Home Collection

🩺 Medically Reviewed By

Overview

To identify genetic variations in the TLR3 gene that may increase susceptibility to Herpes Simplex Encephalitis Type 2.

Test Code
4965
Price
₹20,000
Sample Type
Blood, Extracted DNA, or FTA Card
Result Time
3 to 4 weeks.
Fasting Required
No
Method
Next-Generation Sequencing (NGS)
Step 1

Sample Collection

Genetic counseling session recommended.

Method: Venipuncture or FTA Card

Step 2

Laboratory Analysis

Blood sample collection via venipuncture or FTA card.

Step 3

Report Delivery

Sample sent to lab for analysis.

Timeline: 3 to 4 weeks.

Patient Instructions

1
Before the Test:Genetic counseling and informed consent.
2
During the Test:DNA extraction and sequencing.
3
After the Test:Report generation and interpretation.

About This Test

Who Should Get This Test

To identify genetic variations in the TLR3 gene that may increase susceptibility to Herpes Simplex Encephalitis Type 2.

How to Prepare

  • Ensure proper sample labeling
  • Follow aseptic techniques
  • Store sample at appropriate temperature

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"Genetic testing for TLR3 gene variations can help identify individuals at risk for Herpes Simplex Encephalitis Type 2, allowing for early intervention and management."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood, Extracted DNA, or FTA Card
Collection MethodVenipuncture or FTA Card

Sample Stability

Blood sample stable for 48 hours at room temperature
FTA card stable for longer periods
Sample Rejection Criteria:
  • Hemolyzed sample
  • Insufficient sample volume
  • Improper labeling

Understanding Your Results

Results indicate the presence or absence of genetic variations in the TLR3 gene associated with increased susceptibility to HSE-2.
Positive result: Increased susceptibility, recommend clinical monitoring
Negative result: No increased susceptibility based on known variants
Variant of uncertain significance: Further testing may be needed
⚠️ When to Consult a Doctor:

If you have a family history of HSE-2 or experience symptoms like fever, headache, seizures, consult a neurologist or geneticist.

Limitations

  • Test only assesses TLR3 gene variations
  • Does not diagnose active infection
  • Genetic susceptibility does not guarantee disease development

Risks & Considerations

  • Minimal risk from blood draw
  • Psychological impact of genetic results

Interfering Factors

  • Sample contamination
  • DNA degradation

Frequently Asked Questions

What is the TLR3 gene and its role in HSE-2?
The TLR3 gene produces a protein involved in the immune response to viral infections. Variations in this gene can impair the response to herpes simplex virus, increasing susceptibility to Herpes Simplex Encephalitis Type 2.
Who should consider getting this genetic test?
Individuals with a family history of HSE-2, recurrent herpes infections, or neurological symptoms should consider this test for risk assessment.
How is the test performed?
The test uses next-generation sequencing (NGS) to analyze DNA from blood samples for variations in the TLR3 gene.
What sample is required for the test?
Blood, extracted DNA, or one drop of blood on an FTA card can be used.
Is fasting required before the test?
No, fasting is not required for this genetic test.
How long does it take to receive the results?
Results are typically available in 3 to 4 weeks after sample collection.
What does a positive result mean?
A positive result indicates genetic variations in the TLR3 gene that may increase susceptibility to HSE-2, but it does not diagnose active infection.
Can this test diagnose active HSE-2?
No, this test assesses genetic susceptibility only. Active infection diagnosis requires clinical evaluation and other tests like PCR.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection for online bookings across India.
What is the cost of the test?
The test costs INR 20,000 at DNA Labs India.
Is the test covered by insurance schemes like PMJAY?
Coverage depends on the insurance scheme. It is recommended to check with your provider for specific details.
How accurate is the NGS genetic test for TLR3 variations?
NGS technology is highly accurate for detecting genetic variations, but results should be interpreted in the context of clinical history and genetic counseling.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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Your medical data is protected under Indian law.

Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

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