TNFRSF13B Gene Immunodeficiency common variable type 2 NGS Genetic Test
Short Name: TNFRSF13B CVID2 NGS Genetic Test
Also known as: CVID2, Common Variable Immunodeficiency Type 2
TNFRSF13B Gene Immunodeficiency common variable type 2 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next Generation Sequencing (NGS) on Blood, Extracted DNA, or FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
To identify mutations in the TNFRSF13B gene for the diagnosis of Common Variable Immunodeficiency Type 2 (CVID2).
- Test Code
- 2427
- Price
- ₹20,000
- Sample Type
- Blood, Extracted DNA, or FTA Card
- Result Time
- 3 to 4 weeks
- Fasting Required
- No
- Method
- Next Generation Sequencing (NGS)
Sample Collection
Provide detailed clinical history and undergo genetic counseling to draw a family pedigree chart.
Method: Venipuncture
Laboratory Analysis
Blood sample collection via venipuncture or use of FTA card.
Report Delivery
Sample sent to laboratory for NGS analysis.
Timeline: 3 to 4 weeks
Patient Instructions
About This Test
Who Should Get This Test
To identify mutations in the TNFRSF13B gene for the diagnosis of Common Variable Immunodeficiency Type 2 (CVID2).
How to Prepare
- No fasting typically required for genetic tests
- Bring identification and doctor's prescription
- Inform about any medications or recent infections
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Early diagnosis through genetic testing is crucial for managing CVID2 and improving patient outcomes with tailored treatments."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed sample
- Insufficient sample volume
- Incorrect sample type
Understanding Your Results
Pathogenic variant detected
Confirms diagnosis of CVID2. Consult a geneticist for management and family counseling.
No pathogenic variant detected
CVID2 unlikely based on this gene, but clinical correlation and further testing may be advised.
Variant of uncertain significance
Further testing, family studies, or clinical follow-up recommended for clarification.
If symptoms persist, genetic test results are positive, or for family planning advice, consult a geneticist or immunologist.
Limitations
- ⚠May not detect all genetic variants
- ⚠Requires genetic counseling for accurate interpretation
Risks & Considerations
- ●Minimal risk from blood draw such as bruising
- ●Psychological impact of genetic results
Interfering Factors
- ●Sample contamination
- ●Degraded DNA
Frequently Asked Questions
What is TNFRSF13B Gene Immunodeficiency Common Variable Type 2?
What are the common symptoms of CVID2?
How is CVID2 diagnosed?
What is the cost of the NGS Genetic Test for CVID2 in India?
Is home sample collection available for this test?
How long does it take to receive the test results?
What sample type is required for the test?
Is fasting required before the test?
Who should consider getting this genetic test?
What does a positive test result mean?
Are there any risks associated with the test?
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