TNFRSF13C Gene Immunodeficiency common variable type 4 NGS Genetic Test
Short Name: TNFRSF13C CVID4 NGS Test
Also known as: CVID4 Genetic Test, TNFRSF13C Mutation Analysis, Common Variable Immunodeficiency Type 4 Test
TNFRSF13C Gene Immunodeficiency common variable type 4 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of the TNFRSF13C Gene NGS Genetic Test is to detect genetic mutations in the TNFRSF13C gene responsible for Immunodeficiency Common Variable Type 4 (CVID4). This test aids in confirming diagnosis, assessing disease risk, guiding personalized treatment, and facilitating genetic counseling for affected individuals and their families.
- Test Code
- 2426
- ICD Code
- D80.1
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 weeks
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
No specific preparation required. Provide clinical history and family pedigree chart as advised during genetic counseling.
Method: Venipuncture or finger-prick
Laboratory Analysis
A blood sample will be collected via venipuncture or finger-prick onto an FTA card. The process is quick and minimally invasive.
Report Delivery
Apply pressure to the collection site to prevent bruising. Store samples as instructed and transport to the lab promptly.
Timeline: 3 to 4 weeks
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the TNFRSF13C Gene NGS Genetic Test is to detect genetic mutations in the TNFRSF13C gene responsible for Immunodeficiency Common Variable Type 4 (CVID4). This test aids in confirming diagnosis, assessing disease risk, guiding personalized treatment, and facilitating genetic counseling for affected individuals and their families.
How to Prepare
- Ensure proper identification of the patient
- Use sterile equipment for blood collection
- Label samples correctly with patient details
- Follow ambient temperature storage guidelines
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"This NGS genetic test is essential for confirming TNFRSF13C-related immunodeficiency, enabling targeted therapy and genetic counseling for affected families."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted samples
- Insufficient sample volume
- Improperly labeled or contaminated samples
Understanding Your Results
Pathogenic variant detected
Confirms diagnosis of TNFRSF13C-related CVID4. Recommend immunoglobulin therapy and genetic counseling.
Variant of uncertain significance (VUS)
Further testing or family studies may be needed. Clinical correlation is advised.
No pathogenic variant detected
Does not rule out CVID4 entirely; consider other genetic or clinical causes.
Consult a doctor if you experience recurrent infections, chronic symptoms suggestive of immunodeficiency, or have a family history of CVID. Genetic counseling is recommended before and after testing.
Limitations
- ⚠May not detect all genetic variants or structural changes
- ⚠Results require interpretation by a geneticist or healthcare provider
- ⚠Does not rule out other immunodeficiency disorders
- ⚠Genetic counseling is essential for understanding implications
Risks & Considerations
- ●Minor pain or bruising at the blood draw site
- ●Rare risk of infection or fainting
- ●Psychological impact of genetic results
Interfering Factors
- ●Poor sample quality (e.g., hemolyzed blood)
- ●Contamination during sample collection or processing
- ●Insufficient DNA quantity
- ●Recent blood transfusions may affect results
Frequently Asked Questions
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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
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