TNFRSF1A Gene Periodic fever autosomal dominant NGS Genetic Test
Short Name: TNFRSF1A Gene Test
Also known as: TNFRSF1A Mutation Test, Periodic Fever Syndrome Genetic Test, TNFRSF1A-related Autoinflammatory Disorder Test
TNFRSF1A Gene Periodic fever autosomal dominant NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks from sample collection. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of this test is to diagnose TNFRSF1A gene-related periodic fever syndrome by detecting pathogenic mutations through NGS, enabling early intervention, personalized management, and genetic counseling for affected individuals and their families.
- Test Code
- 2203
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 weeks from sample collection
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
Provide complete clinical history of the patient and family members. Undergo a genetic counseling session to draw a pedigree chart of affected family members.
Method: Venipuncture or blood spot collection
Laboratory Analysis
Blood sample collection via venipuncture or blood spot on FTA card as per standard procedures.
Report Delivery
Store sample appropriately and transport to laboratory. Follow up for report after 3 to 4 weeks.
Timeline: 3 to 4 weeks from sample collection
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to diagnose TNFRSF1A gene-related periodic fever syndrome by detecting pathogenic mutations through NGS, enabling early intervention, personalized management, and genetic counseling for affected individuals and their families.
How to Prepare
- No fasting required before sample collection
- Bring valid ID and physician's prescription
- Ensure sample is correctly labeled with patient details
- For home collection, ensure a clean and safe environment
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Early genetic testing for TNFRSF1A mutations can guide personalized treatment and management of periodic fever episodes, improving patient outcomes."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted blood sample
- Insufficient sample volume
- Incorrect labeling or identification mismatch
- Sample contaminated or improperly stored
Understanding Your Results
Confirms diagnosis of TNFRSF1A-related periodic fever syndrome. Genetic counseling and clinical management recommended.
Result type: Positive (Pathogenic variant detected)
Does not rule out other periodic fever syndromes; clinical correlation and further testing may be needed.
Result type: Negative (No pathogenic variant detected)
Genetic variant identified but clinical significance unclear. Family studies and follow-up recommended.
Result type: Variant of Uncertain Significance
Consult a geneticist or healthcare provider immediately after receiving test results to discuss management options, treatment, and genetic counseling for the patient and family members.
Limitations
- ⚠May not detect all types of genetic variants (e.g., large deletions)
- ⚠Requires genetic counseling for accurate interpretation
- ⚠Results should be correlated with clinical history and symptoms
Risks & Considerations
- ●Minimal risk associated with blood draw (e.g., slight pain, bruising)
- ●No significant risks from the genetic test itself
Interfering Factors
- ●Contaminated DNA sample
- ●Improper storage or handling of sample
- ●Insufficient sample volume
Compare With Similar Tests
| Test | TNFRSF1A Gene Periodic fever autosomal dominant NGS Genetic Test | ||
|---|---|---|---|
| Comparison | TNFRSF1A Gene Periodic fever autosomal dominant NGS Genetic Test |
Frequently Asked Questions
What is the TNFRSF1A Gene Periodic Fever Test?
Who should consider getting this test?
What symptoms indicate TNFRSF1A-related periodic fever?
How is the test performed?
What is the cost of the TNFRSF1A Gene Test?
Is this test covered by insurance?
How long does it take to get results?
Is home sample collection available?
What are the risks of the test?
How should I interpret the test results?
How does this test differ from other genetic tests for periodic fever?
Where can I get the TNFRSF1A Gene Test done?
Related Tests
Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
Book Your Test
Enter your details and we'll connect you within 15 minutes.