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DNA Labs India

TTC19 Gene Mitochondrial complex III deficiency, nuclear type 2 NGS Genetic Test

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TTC19 Gene Mitochondrial complex III deficiency, nuclear type 2 NGS Genetic Test

Short Name: TTC19 Mitochondrial Complex III Deficiency Test

Also known as: Mitochondrial Complex III Deficiency Genetic Test

TTC19 Gene Mitochondrial complex III deficiency, nuclear type 2 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.

NGS Genetic Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

The purpose of this test is to identify mutations in the TTC19 gene that cause mitochondrial complex III deficiency, nuclear type 2, aiding in diagnosis, treatment planning, and genetic counseling.

Test Code
1721
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
3 to 4 Weeks
Fasting Required
No
Method
Next-Generation Sequencing (NGS)
Step 1

Sample Collection

No specific preparation required. Inform the lab of any medications or recent treatments.

Method: Venipuncture or FTA card spot

Step 2

Laboratory Analysis

Blood sample will be drawn via venipuncture or collected on FTA card.

Step 3

Report Delivery

Apply pressure to the puncture site to stop bleeding. Keep the area clean.

Timeline: 3 to 4 Weeks

Patient Instructions

1
Before the Test:Genetic counseling session recommended to understand implications.
2
During the Test:Sample collection process is non-invasive or minimally invasive.
3
After the Test:Results will be delivered within 3-4 weeks. Follow-up with physician advised.

About This Test

Who Should Get This Test

The purpose of this test is to identify mutations in the TTC19 gene that cause mitochondrial complex III deficiency, nuclear type 2, aiding in diagnosis, treatment planning, and genetic counseling.

How to Prepare

  • Fast for 4 hours if advised
  • Use sterile collection tubes
  • Label sample correctly

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Genetic testing for mitochondrial disorders is crucial for accurate diagnosis, enabling personalized treatment and genetic counseling."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Collection MethodVenipuncture or FTA card spot

Sample Stability

Room temperature24 hours for blood
Sample Rejection Criteria:
  • Hemolyzed samples
  • Insufficient volume
  • Improperly labeled samples

Understanding Your Results

Results are interpreted based on the presence or absence of pathogenic variants in the TTC19 gene.
📊

Negative

No pathogenic variants detected. Clinical correlation needed.

📊

Positive

Pathogenic variant detected. Consistent with mitochondrial complex III deficiency. Genetic counseling recommended.

⚠️ When to Consult a Doctor:

If you experience symptoms of mitochondrial disorder or have a family history, consult a neurologist or geneticist.

Limitations

  • ⚠May not detect all genetic variants
  • ⚠Results require clinical correlation
  • ⚠Does not rule out other genetic disorders

Risks & Considerations

  • ●Minimal physical risk from blood draw
  • ●Psychological impact of genetic results
  • ●Potential for inconclusive results

Interfering Factors

  • ●Poor sample quality
  • ●Contamination
  • ●Recent blood transfusion

Compare With Similar Tests

TestTTC19 Gene Mitochondrial complex III deficiency, nuclear type 2 NGS Genetic TestFull Mitochondrial Genome Sequencing
ComparisonTTC19 Gene Mitochondrial complex III deficiency, nuclear type 2 NGS Genetic TestCovers mitochondrial DNA, while TTC19 test focuses on nuclear gene.

Frequently Asked Questions

What is the TTC19 Gene Mitochondrial Complex III Deficiency NGS Genetic Test?
It is a genetic test using Next-Generation Sequencing to detect mutations in the TTC19 gene that cause mitochondrial complex III deficiency, nuclear type 2.
How much does the test cost?
The test costs INR 20,000 at DNA Labs India.
What sample is required for the test?
Blood, extracted DNA, or one drop of blood on an FTA card.
How long does it take to get results?
Results are typically available within 3 to 4 weeks.
Is home sample collection available?
Yes, free home collection is available across India for online bookings.
What are the symptoms of mitochondrial complex III deficiency?
Symptoms include muscle weakness, fatigue, exercise intolerance, developmental delays, neurological issues, respiratory problems, and heart complications.
How is the test performed?
The test uses NGS technology to analyze the TTC19 gene for mutations.
What does a positive result mean?
A positive result indicates pathogenic variants in the TTC19 gene, consistent with mitochondrial complex III deficiency. Genetic counseling is recommended.
Can this test be done on children?
Yes, the test can be performed on individuals of all ages, but consultation with a healthcare provider is advised.
Is the test covered by insurance?
Coverage depends on the insurance policy. Check with your provider; schemes like PMJAY or CGHS may not cover it.
What is the accuracy of the test?
NGS technology offers high accuracy in detecting genetic mutations, but results should be correlated with clinical findings.
How can I prepare for the test?
No specific preparation is needed, but genetic counseling before the test is recommended.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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