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UCHL1 Gene PARK5 Parkinson NGS Genetic Test

DNA Labs India | ISO 9001:2015 Certified

UCHL1 Gene PARK5 Parkinson NGS Genetic Test

Short Name: UCHL1 Gene PARK5 Parkinson Test

Also known as: UCHL1 Gene Mutation Test, PARK5 Genetic Test, Parkinson's Genetic Screening

UCHL1 Gene PARK5 Parkinson NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in Results are typically available within 3 to 4 weeks after sample receipt.. Free home collection in 300+ cities across India.

Next Generation Sequencing (NGS)Adults🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

The purpose of this test is to identify mutations in the UCHL1 gene that may increase a person's risk of developing Parkinson's disease, enabling early intervention, genetic counseling, and informed healthcare decisions.

Test Code
1788
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
Results are typically available within 3 to 4 weeks after sample receipt.
Fasting Required
No
Method
Next Generation Sequencing (NGS)
Step 1

Sample Collection

No special preparation is required. Provide clinical history and undergo genetic counseling as per protocol.

Method: Venipuncture or FTA Card

Step 2

Laboratory Analysis

A small blood sample will be drawn by a trained phlebotomist or you may provide a saliva/DNA sample on an FTA card.

Step 3

Report Delivery

The sample is labeled, stored at ambient temperature, and transported to the laboratory for NGS analysis.

Timeline: Results are typically available within 3 to 4 weeks after sample receipt.

Patient Instructions

1
Before the Test:Undergo genetic counseling, provide informed consent, and share clinical and family history with your physician.
2
During the Test:Sample collection via blood draw or saliva; minimal discomfort; test is non-invasive after collection.
3
After the Test:Sample is processed in the lab; results are reviewed by a geneticist; genetic counseling is provided post-test.

About This Test

Who Should Get This Test

The purpose of this test is to identify mutations in the UCHL1 gene that may increase a person's risk of developing Parkinson's disease, enabling early intervention, genetic counseling, and informed healthcare decisions.

How to Prepare

  • Ensure the sample is collected in a sterile environment
  • Label the sample with patient details and test information
  • For blood collection, use appropriate anticoagulant tubes
  • For FTA card, follow the drop-blood instructions provided

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Genetic testing for UCHL1 mutations can aid in early identification of individuals at risk for PARK5 Parkinson's disease, enabling proactive management and genetic counseling."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
Collection MethodVenipuncture or FTA Card

Sample Stability

Blood samples are stable for up to 48 hours at room temperature
Extracted DNA should be stored at -20°C for long-term stability
FTA cards can be stored at room temperature for several weeks
Sample Rejection Criteria:
  • Hemolyzed or clotted blood samples
  • Insufficient sample volume
  • Improperly labeled or contaminated samples
  • Samples without required clinical information

Understanding Your Results

Results from the UCHL1 Gene PARK5 Parkinson NGS Genetic Test are interpreted based on the presence or absence of pathogenic mutations in the UCHL1 gene.
📊

No pathogenic variant detected

Low genetic risk for PARK5 Parkinson's disease based on UCHL1 gene analysis. Clinical correlation is recommended.

📊

Pathogenic variant detected

Increased genetic risk for PARK5 Parkinson's disease. Genetic counseling and further clinical evaluation are advised.

📊

Variant of uncertain significance (VUS)

The clinical significance is unclear. Repeat testing or family studies may be needed for clarification.

⚠️ When to Consult a Doctor:

Consult a doctor if you have a family history of Parkinson's disease, experience symptoms like tremors or stiffness, or receive a positive or VUS result from this test for personalized management.

Limitations

  • ⚠This test only analyzes the UCHL1 gene; other genetic factors contributing to Parkinson's disease are not assessed
  • ⚠A negative result does not rule out Parkinson's disease, as other causes may be involved
  • ⚠Test results should be interpreted in conjunction with clinical evaluation and family history

Risks & Considerations

  • ●Minimal risk from blood draw, such as slight pain or bruising
  • ●Psychological impact of genetic risk information; counseling is recommended
  • ●No direct physical risks from the genetic test itself

Interfering Factors

  • ●Hemolyzed or degraded DNA samples may affect test accuracy
  • ●Improper sample collection or storage
  • ●Presence of contaminating substances in the sample

Compare With Similar Tests

TestUCHL1 Gene PARK5 Parkinson NGS Genetic TestSNCA Gene Parkinson's Genetic TestLRRK2 Gene Parkinson's Genetic TestPARK2 Gene Parkinson's Genetic TestParkinson's Disease Genetic Panel
ComparisonUCHL1 Gene PARK5 Parkinson NGS Genetic Test

Frequently Asked Questions

What is the UCHL1 Gene PARK5 Parkinson NGS Genetic Test?
This test uses Next Generation Sequencing to detect mutations in the UCHL1 gene, which are associated with an increased risk of developing PARK5 Parkinson's disease.
Who should consider getting this test?
Individuals with a family history of Parkinson's disease, early symptoms, or known UCHL1 mutations in their family may benefit from this test for risk assessment.
How is the test performed?
A blood or saliva sample is collected and analyzed using NGS technology in our accredited laboratory to identify UCHL1 gene mutations.
What does a positive result mean?
A positive result indicates a pathogenic mutation in the UCHL1 gene, suggesting an increased genetic risk for Parkinson's disease. It is not a diagnosis but warrants further clinical evaluation and genetic counseling.
What if the test is negative?
A negative result means no pathogenic UCHL1 mutations were detected, indicating a lower genetic risk based on this gene. However, Parkinson's disease can have other causes.
Is the test painful?
The test involves a routine blood draw or saliva collection, which may cause minor discomfort but is generally not painful.
How long does it take to get results?
Results are typically available within 3 to 4 weeks after the sample is received at the laboratory.
Is genetic counseling included?
Yes, DNA Labs India provides a genetic counseling session before and after the test to discuss results, implications, and next steps.
Can the test be done at home?
Yes, free home sample collection is available for this test across many cities in India. Book online to schedule a collection.
What is the cost of the test?
The UCHL1 Gene PARK5 Parkinson NGS Genetic Test costs INR 20,000, inclusive of sample collection, testing, and reporting.
Is this test covered by insurance?
Coverage varies by insurance provider. DNA Labs India provides documentation for reimbursement claims, but direct coverage is not guaranteed.
What should I do after receiving the results?
Discuss the results with a healthcare provider or geneticist for personalized advice, possible further testing, and management strategies.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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