UNC13D Gene Hemophagocytic lymphohistiocytosis type 3 NGS Genetic Test
Short Name: UNC13D HLH Type 3 NGS Test
Also known as: HLH Type 3 Genetic Test, UNC13D Mutation Analysis, Familial HLH Type 3 Test
UNC13D Gene Hemophagocytic lymphohistiocytosis type 3 NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 Weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SULOCHANA HEMCHANDRA HOLLA
Consultant Medical Geneticist · Reg: 8532
Last reviewed: September 7, 2026
Overview
The purpose of the UNC13D Gene HLH Type 3 NGS Genetic Test is to identify mutations in the UNC13D gene that cause hemophagocytic lymphohistiocytosis type 3, aiding in the diagnosis, management, and genetic counseling for affected individuals and their families.
- Test Code
- 4959
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 Weeks
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
Genetic counseling is recommended to discuss test implications and family history.
Laboratory Analysis
A blood sample will be collected via venipuncture or a drop on an FTA card.
Report Delivery
Apply pressure to the puncture site to prevent bruising. Store sample as instructed.
Timeline: 3 to 4 Weeks
Patient Instructions
About This Test
Who Should Get This Test
The purpose of the UNC13D Gene HLH Type 3 NGS Genetic Test is to identify mutations in the UNC13D gene that cause hemophagocytic lymphohistiocytosis type 3, aiding in the diagnosis, management, and genetic counseling for affected individuals and their families.
How to Prepare
- Ensure proper identification of the patient
- Use sterile collection equipment
- Label the sample correctly with patient details
Doctor's Notes
Reviewed by Dr SULOCHANA HEMCHANDRA HOLLA — MBBS, MD (Medical Genetics) · Reg. No. 8532
"Early genetic testing for UNC13D mutations is crucial for diagnosing HLH Type 3 and guiding treatment decisions, especially in families with a history of immune disorders."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted sample
- Incorrect sample type or container
- Insufficient sample volume
Understanding Your Results
Positive for pathogenic mutation
Confirms diagnosis of HLH type 3; genetic counseling and family screening recommended.
Negative for pathogenic mutation
No UNC13D mutations detected; consider other genetic or clinical causes for symptoms.
Variant of uncertain significance
Further testing or family studies may be needed for clarification.
Consult a doctor if you experience symptoms of HLH, have a family history of the disorder, or need guidance on test results and management.
Limitations
- ⚠May not detect all types of mutations in the UNC13D gene
- ⚠Results require interpretation by a genetic specialist
- ⚠Does not rule out other forms of HLH or immune disorders
Risks & Considerations
- ●Minor bruising or pain at the blood draw site
- ●Rare risk of infection
- ●Emotional impact of genetic results
Interfering Factors
- ●Contaminated or degraded DNA sample
- ●Insufficient sample volume
- ●Recent blood transfusion may affect results
Frequently Asked Questions
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Reference Laboratory Services
We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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