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DNA Labs India

Vitamin B12 Binding Capacity Unsaturated Transcobalamin Test

DNA Labs India | ISO 9001:2015 Certified

Vitamin B12 Binding Capacity Unsaturated Transcobalamin Test

Short Name: Unsaturated Transcobalamin Test

Also known as: Unsaturated Transcobalamin, Vitamin B12 Binding Capacity, UB12BC

Vitamin B12 Binding Capacity Unsaturated Transcobalamin Test test available at DNA Labs India for ₹18,000. Uses Radiobinding Assay on Serum samples. Results in Samples are shipped to the referral laboratory. Reports are dispatched after 2-3 weeks from the sample receiving cutoff date.. Free home collection in 300+ cities across India.

Blood Test🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SHAILAJA RAGHUNATH MURDESHWAR

Dr SHAILAJA RAGHUNATH MURDESHWAR

Consultant Physician · Reg: 8052

Last reviewed: September 7, 2026

Overview

To measure the amount of unsaturated transcobalamin in serum, supporting the diagnosis of vitamin B12 deficiency and helping differentiate between nutritional deficiency, malabsorption, transcobalamin deficiency, and myeloproliferative disorders.

Test Code
3733
Price
₹18,000
Sample Type
Serum
Result Time
Samples are shipped to the referral laboratory. Reports are dispatched after 2-3 weeks from the sample receiving cutoff date.
Fasting Required
No
Method
Radiobinding Assay
Step 1

Sample Collection

No fasting is required. Ensure the Test Send Out Consent Form (Form 35) is duly filled before sample submission.

Method: Venipuncture

Step 2

Laboratory Analysis

A 2 mL serum sample will be collected from a vein by a trained phlebotomist.

Step 3

Report Delivery

There are no restrictions after sample collection. You may resume normal activities.

Timeline: Samples are shipped to the referral laboratory. Reports are dispatched after 2-3 weeks from the sample receiving cutoff date.

Patient Instructions

1
Before the Test:No special preparation is required. Inform your doctor about any medications, supplements, or herbal products you are taking.
2
During the Test:A blood sample will be drawn from a vein in your arm. The procedure usually takes a few minutes.
3
After the Test:You can resume normal activities immediately after the blood draw. Apply pressure to the puncture site if needed to reduce bruising.

About This Test

Who Should Get This Test

To measure the amount of unsaturated transcobalamin in serum, supporting the diagnosis of vitamin B12 deficiency and helping differentiate between nutritional deficiency, malabsorption, transcobalamin deficiency, and myeloproliferative disorders.

How to Prepare

  • Duly filled Test Send Out Consent Form (Form 35) is mandatory.
  • Sample should be shipped refrigerated or frozen as per stability guidelines.
  • Store serum at room temperature for up to 8 hours only, refrigerate for up to 4 days, or freeze for up to 30 days.

Doctor's Notes

Reviewed by — MBBS, MD (General Medicine) · Reg. No. 8052

"A low or high unsaturated transcobalamin level must not be used alone. A complete blood count, peripheral smear, serum vitamin B12, and clinical picture are essential for accurate interpretation."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeSerum
Sample Volume2 mL (1 mL min.) serum from 1 SST
ContainerSST (Serum Separator Tube)
Collection MethodVenipuncture

Sample Stability

Room Temperature
Refrigerator
Frozen
Sample Rejection Criteria:
  • Missing Test Send Out Consent Form (Form 35)
  • Improperly labelled or mismatched sample
  • Haemolysed serum sample
  • Samples not stored or transported according to stability requirements

Understanding Your Results

Interpretation of this test should be performed by a qualified clinician alongside serum vitamin B12 levels, blood counts, and clinical findings.
Increased unsaturated transcobalamin concentrations are associated with myeloproliferative disorders.
Decreased concentrations may be seen in megaloblastic anemia or transcobalamin deficiency.
A normal result with persistent clinical suspicion requires further evaluation by the referring physician.
⚠️ When to Consult a Doctor:

If you have persistent fatigue, neurological symptoms, anaemia, or other signs suggestive of vitamin B12 deficiency, consult your physician for clinical evaluation and appropriate testing.

Limitations

  • ⚠Unsaturated transcobalamin result alone does not establish a diagnosis.
  • ⚠Result must be interpreted with serum vitamin B12, complete blood count, clinical symptoms, and physician assessment.

Risks & Considerations

  • ●Mild discomfort or pain at the puncture site
  • ●Bruising or bleeding at the site
  • ●Rare risk of infection or dizziness

Interfering Factors

  • ●Recent vitamin B12 supplementation may alter the binding capacity result.
  • ●Incorrect sample storage or transport beyond the recommended time may affect accuracy.
  • ●Concurrent medications should be reported to the laboratory and treating physician.

Frequently Asked Questions

What is the Vitamin B12 Binding Capacity Unsaturated Transcobalamin Test?
This test measures the amount of unsaturated transcobalamin in the blood. Transcobalamin is the protein responsible for transporting vitamin B12 to the cells where it is needed.
What is the cost of this test at DNA Labs India?
The cost is INR 18,000. Online bookings include free home sample collection in select cities across India.
Do I need to fast for this test?
No, fasting is not required for this test. However, a duly filled Test Send Out Consent Form (Form 35) is mandatory.
What sample type is needed for the test?
The test requires 2 mL (minimum 1 mL) serum from one SST. The sample should be shipped refrigerated or frozen.
What is the turnaround time for results?
The sample should reach the lab by the 7th of the month. The report is issued after 2–3 weeks.
Why is this test done?
This test is done to diagnose vitamin B12 deficiency and to help determine the cause, such as nutritional deficiency, malabsorption, transcobalamin deficiency, or myeloproliferative disorder.
What are the common symptoms of vitamin B12 deficiency?
Common symptoms include fatigue, weakness, shortness of breath, dizziness, pale skin, tingling or numbness in hands and feet, muscle weakness, appetite loss, weight loss, depression, and memory loss.
What does an increased unsaturated transcobalamin concentration mean?
Increased concentrations are associated with myeloproliferative disorders.
What does a decreased unsaturated transcobalamin concentration mean?
Decreased concentrations may be seen in individuals with megaloblastic anemia or transcobalamin deficiency.
Is home sample collection available for this test?
Yes, DNA Labs India offers free home sample collection for online bookings for the Vitamin B12 Binding Capacity Unsaturated Transcobalamin Test across numerous cities in India.
Can I take this test without a doctor's prescription?
This is a physician-referred test. A doctor should evaluate the clinical need and interpret the result in the context of your health condition.
What is Form 35?
Form 35 is the Test Send Out Consent Form. It must be duly filled and submitted before sample collection; without it, the test cannot be processed.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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