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DNA Labs India

Vitamin B12 Cyanocobalamin Test

DNA Labs India | ISO 9001:2015 Certified

Vitamin B12 Cyanocobalamin Test

Short Name: Vitamin B12 Cyanocobalamin

Also known as: Cyanocobalamin Test, Vitamin B12 Assay, Serum B12 Level, Cobalamin Test

Vitamin B12 Cyanocobalamin Test test available at DNA Labs India for ₹1,287. Uses Chemiluminescent Immunoassay on Serum samples. Results in Reports are generated daily; typically available on the same day or the next working day.. Free home collection in 300+ cities across India.

Quantitative Blood TestAll age groups🏠 Home Collection

🩺 Medically Reviewed By

Overview

This assay is useful for investigating Macrocytic anemia and as a workup of deficiencies seen in Megaloblastic anemia.

Test Code
3736
CPT Code
82607
ICD Code
D51.9
Price
₹1,287
Sample Type
Serum
Result Time
Reports are generated daily; typically available on the same day or the next working day.
Fasting Required
No
Method
Chemiluminescent Immunoassay
Step 1

Sample Collection

Overnight fasting is preferred but not mandatory. Inform your doctor about all medications, supplements, and any relevant medical conditions. The sample should be protected from light after collection.

Method: Venipuncture

Step 2

Laboratory Analysis

A trained phlebotomist will collect approximately 3 mL of blood from a vein in your arm. The procedure takes only a few minutes.

Step 3

Report Delivery

You can resume normal activities immediately after the blood draw. If you feel dizzy or have prolonged bleeding, inform the phlebotomist.

Timeline: Reports are generated daily; typically available on the same day or the next working day.

Patient Instructions

1
Before the Test:Overnight fasting is preferred but not mandatory. Please inform your doctor about any medications or supplements you are taking.
2
During the Test:A blood sample is collected from a vein in the arm. The process is quick and usually causes mild, brief discomfort.
3
After the Test:No special precautions are required. You may leave the facility and continue your daily activities unless your doctor advises otherwise.

About This Test

Who Should Get This Test

This assay is useful for investigating Macrocytic anemia and as a workup of deficiencies seen in Megaloblastic anemia.

How to Prepare

  • Overnight fasting is preferred.
  • Wrap the sample in aluminium foil to protect it from light.
  • Send the sample refrigerated or frozen as advised.
  • Please mention any ongoing supplements or medicines to your doctor.

Doctor's Notes

Reviewed by — MBBS, MD (General Medicine) · Reg. No. 8052

"I recommend early testing for patients with macrocytic anemia or suggestive neurological symptoms. A single vitamin B12 level is not enough; clinical correlation is essential."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeSerum
Sample Volume3 mL (1 mL min.) serum from 1 SST
ContainerSST (Serum Separator Tube)
Collection MethodVenipuncture

Sample Stability

Room Temperature: 8 hours
Refrigerator: 48 hours
Frozen: 8 weeks
Protect from light at all times
Sample Rejection Criteria:
  • Sample exposed to light for a prolonged period
  • Hemolyzed or improperly separated sample
  • Incorrect labelling or patient identification
  • Sample received after prolonged delayed transport

Understanding Your Results

The results of the Vitamin B12 Cyanocobalamin test should be interpreted by a qualified doctor in the context of the patient's symptoms, medical history, and additional laboratory findings.
📊

Adequate serum vitamin B12 level.

📊

May be equivocal; additional tests such as MMA or homocysteine may be considered.

📊

Likely vitamin B12 deficiency; clinical correlation and further evaluation are recommended.

📊

May be related to supplementation or other conditions; clinical correlation advised.

⚠️ When to Consult a Doctor:

If your vitamin B12 level is below the reference range or if you experience symptoms such as persistent fatigue, numbness, tingling, or memory problems, consult a doctor for proper evaluation and treatment.

Limitations

  • Serum vitamin B12 alone may not fully reflect tissue B12 status.
  • Borderline results may require additional tests such as methylmalonic acid or homocysteine.
  • Reference ranges may differ between laboratories.

Risks & Considerations

  • Minor pain or discomfort at the needle site
  • Small bruise or swelling after blood collection
  • Rare risk of infection or lightheadedness

Interfering Factors

  • Exposure of the sample to light may falsely lower vitamin B12 levels.
  • Prolonged storage at room temperature can affect sample stability.
  • Certain medications and supplements may alter measured B12 levels.
  • Recent food intake may affect results in a fasting-preference protocol.

Frequently Asked Questions

What is the Vitamin B12 Cyanocobalamin test?
It is a blood test that measures the level of vitamin B12 in your blood. It is used to help diagnose vitamin B12 deficiency and assess causes of anemia such as macrocytic or megaloblastic anemia.
Why is vitamin B12 important for the body?
Vitamin B12 is essential for red blood cell formation, DNA synthesis, and normal neurological function. A deficiency can cause anemia and nerve damage.
What are the common symptoms of vitamin B12 deficiency?
Common symptoms include fatigue, weakness, pale skin, shortness of breath, dizziness, loss of appetite, weight loss, numbness or tingling in the hands and feet, difficulty walking, mood changes, poor memory, and cognitive decline.
What is the cost of the test at DNA Labs India?
The special discounted price is INR 1287 for an online booking, which includes free home sample collection in many cities across India.
Is fasting required for the Vitamin B12 test?
Overnight fasting is preferred but not mandatory. Please follow the specific instructions given by your diagnostic center.
What sample is collected for this test?
A blood sample is collected from a vein. The test requires 3 mL of serum and a minimum of 1 mL. The sample is collected in a serum separator tube and should be protected from light.
How is the sample prepared after collection?
The tube should be wrapped in aluminium foil to protect it from light and sent refrigerated or frozen after serum separation. The laboratory uses chemiluminescent immunoassay for testing.
When will I get the report?
Reports are generated daily. Most patients receive results on the same day or the next working day depending on the location and sample pickup time.
What are normal vitamin B12 levels?
Normal serum vitamin B12 levels generally range from 200 to 900 pg/mL. However, reference ranges can differ between laboratories and should be interpreted by the treating doctor.
What does a low vitamin B12 level mean?
A low vitamin B12 level may indicate vitamin B12 deficiency, which can be due to insufficient dietary intake, malabsorption, pernicious anemia, or other medical conditions. Further tests may be needed to find the cause.
Can vitamin B12 deficiency be treated?
Yes. Treatment may include vitamin B12 supplements, dietary changes, or injections depending on the cause and severity. Always follow your doctor's advice.
Are there any risks in this test?
The test is a routine blood draw with minimal risks such as slight pain, bruising, or rarely infection. These risks are generally very low.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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Your medical data is protected under Indian law.

Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

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