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WWOX Gene Spinocerebellar ataxia type 12, autosomal recessive NGS Genetic Test

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WWOX Gene Spinocerebellar ataxia type 12, autosomal recessive NGS Genetic Test

Short Name: SCA12 Genetic Test

Also known as: SCA12 Genetic Test, WWOX Gene Mutation Test, Spinocerebellar Ataxia Type 12 Test

WWOX Gene Spinocerebellar ataxia type 12, autosomal recessive NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in Results are typically available within 3 to 4 weeks after sample collection.. Free home collection in 300+ cities across India.

NGS Genetic TestAll Ages🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SULOCHANA HEMCHANDRA HOLLA

Dr SULOCHANA HEMCHANDRA HOLLA

Consultant Medical Geneticist · Reg: 8532

Last reviewed: September 7, 2026

Overview

To identify pathogenic mutations in the WWOX gene for the diagnosis of Spinocerebellar ataxia type 12, enabling appropriate management, genetic counselling, and family screening.

Test Code
1840
Price
₹20,000
Sample Type
Blood or Extracted DNA or One drop Blood on FTA Card
Result Time
Results are typically available within 3 to 4 weeks after sample collection.
Fasting Required
No
Method
Next-Generation Sequencing (NGS)
Step 1

Sample Collection

Provide clinical history and undergo a genetic counselling session to draw a family pedigree chart.

Method: Venipuncture

Step 2

Laboratory Analysis

A blood sample is collected via venipuncture under sterile conditions.

Step 3

Report Delivery

The sample is transported to the lab for NGS analysis; results are generated within 3-4 weeks.

Timeline: Results are typically available within 3 to 4 weeks after sample collection.

Patient Instructions

1
Before the Test:Consult with a genetic counsellor, provide detailed clinical and family history, and ensure informed consent.
2
During the Test:Sample collection is quick and minimally invasive; typically takes 10-15 minutes.
3
After the Test:Wait for results (3-4 weeks), then follow up with a specialist for interpretation and management planning.

About This Test

Who Should Get This Test

To identify pathogenic mutations in the WWOX gene for the diagnosis of Spinocerebellar ataxia type 12, enabling appropriate management, genetic counselling, and family screening.

How to Prepare

  • No fasting required
  • Ensure proper sample labeling
  • Use recommended containers (EDTA tube or FTA card)
  • Maintain ambient temperature during transport

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"Early genetic testing for SCA12 aids in timely management, symptom control, and informed family planning decisions."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeBlood or Extracted DNA or One drop Blood on FTA Card
ContainerEDTA Tube for Blood
Collection MethodVenipuncture

Sample Stability

Blood: 2-8°C for up to 48 hours
Extracted DNA: -20°C for long-term storage
Sample Rejection Criteria:
  • Hemolyzed or clotted samples
  • Insufficient sample volume
  • Incorrect sample type or container
  • Missing patient information

Understanding Your Results

Results indicate the presence or absence of mutations in the WWOX gene associated with Spinocerebellar ataxia type 12.
📊

Confirms diagnosis of SCA12; recommend genetic counselling, symptom management, and family screening.

📊

No evidence of SCA12; consider other genetic or non-genetic causes if symptoms persist.

📊

Further clinical evaluation and family studies may be needed; consult a geneticist.

⚠️ When to Consult a Doctor:

If you experience symptoms like ataxia, tremors, or speech problems, or have a family history of spinocerebellar ataxia, consult a neurologist or geneticist.

Limitations

  • ⚠May not detect all genetic variants or structural changes
  • ⚠Requires interpretation by a geneticist or clinician
  • ⚠Results should be correlated with clinical findings

Risks & Considerations

  • ●Minor bruising or discomfort at the blood draw site
  • ●Rare risk of infection or hematoma
  • ●Psychological impact of genetic results

Interfering Factors

  • ●Contaminated or degraded DNA sample
  • ●Inadequate sample volume
  • ●Incorrect storage or transport conditions

Frequently Asked Questions

What is Spinocerebellar ataxia type 12 (SCA12)?
SCA12 is a rare genetic disorder affecting the nervous system, causing progressive movement and coordination issues due to WWOX gene mutations.
How is SCA12 diagnosed?
Diagnosis is confirmed through genetic testing, such as NGS, which detects mutations in the WWOX gene with high accuracy.
What is the cost of the WWOX gene test in India?
The NGS Genetic Test for SCA12 at DNA Labs India costs INR 20,000, with home collection available.
Is home sample collection available for this test?
Yes, DNA Labs India offers free home sample collection for online bookings across numerous cities in India.
How long does it take to get the test results?
Results are typically delivered within 3 to 4 weeks after sample collection.
What are the common symptoms of SCA12?
Symptoms include unsteady gait, coordination problems, tremors, speech difficulties, memory issues, and vision impairment.
Is SCA12 inherited?
Yes, SCA12 follows an autosomal recessive inheritance pattern, meaning two mutated gene copies are required for the condition to develop.
Can SCA12 be cured?
There is no cure, but treatments like physical therapy, medications, and counselling can manage symptoms and improve quality of life.
What is NGS genetic testing?
Next-Generation Sequencing (NGS) is a advanced technology that sequences genes to identify mutations accurately.
Do I need a doctor's referral for this test?
While a referral is recommended, especially for genetic counselling, it may not be mandatory; contact DNA Labs India for guidance.
What should I do before getting tested?
Undergo genetic counselling, provide clinical history, and ensure sample collection instructions are followed.
How accurate is the WWOX gene test?
NGS testing is highly accurate, but results should be interpreted by a qualified geneticist in clinical context.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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