ZCCHC12 Gene Mental retardation non-syndromic NGS Genetic Test
Short Name: ZCCHC12 Gene Test
Also known as: ZCCHC12 gene NGS test, ZCCHC12 intellectual disability test, Genetic test for non-syndromic mental retardation
ZCCHC12 Gene Mental retardation non-syndromic NGS Genetic Test test available at DNA Labs India for ₹20,000. Uses Next-Generation Sequencing (NGS) on Blood or Extracted DNA or One drop Blood on FTA Card samples. Results in 3 to 4 weeks. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
To identify pathogenic variants in the ZCCHC12 gene that may cause non-syndromic mental retardation, aiding in diagnosis, management, and family planning.
- Test Code
- 1681
- Price
- ₹20,000
- Sample Type
- Blood or Extracted DNA or One drop Blood on FTA Card
- Result Time
- 3 to 4 weeks
- Fasting Required
- No
- Method
- Next-Generation Sequencing (NGS)
Sample Collection
Provide clinical history of the patient. A genetic counseling session is recommended to draw a pedigree chart of family members affected with similar conditions. No specific preparation is required, but ensure all documentation is ready.
Method: Venipuncture or FTA card collection
Laboratory Analysis
Standard blood draw via venipuncture or collection of a blood drop on FTA card. Ensure proper labeling and handling of the sample.
Report Delivery
Apply pressure to the puncture site to prevent bleeding. Store samples at ambient room temperature as instructed. Await report in 3-4 weeks.
Timeline: 3 to 4 weeks
Patient Instructions
About This Test
Who Should Get This Test
To identify pathogenic variants in the ZCCHC12 gene that may cause non-syndromic mental retardation, aiding in diagnosis, management, and family planning.
How to Prepare
- No fasting required
- Bring clinical history and genetic counseling notes
- Use sterile collection tubes or FTA cards
- Ensure sample is labeled correctly with patient details
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"Genetic testing for the ZCCHC12 gene can help identify underlying genetic causes of intellectual disability, guiding personalized management, family counseling, and early intervention strategies."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or clotted blood samples
- Insufficient sample volume
- Incorrectly labeled or contaminated samples
Understanding Your Results
Consult a geneticist or neurologist if results indicate a pathogenic variant, for personalized management, family risk assessment, and counseling. Also seek consultation if symptoms persist despite negative results.
Limitations
- ⚠May not detect all types of genetic mutations (e.g., large deletions, intronic variants)
- ⚠Results require interpretation by a clinical geneticist
- ⚠Genetic testing cannot predict severity or progression of symptoms
Risks & Considerations
- ●Minimal risk from blood draw (e.g., bruising, infection)
- ●Psychological impact of test results
- ●Potential for uncertain findings requiring further testing
Interfering Factors
- ●Poor sample quality or DNA degradation
- ●Contamination during sample handling
- ●Recent blood transfusion may affect results
Compare With Similar Tests
| Test | ZCCHC12 Gene Mental retardation non-syndromic NGS Genetic Test | FMR1 Gene Test for Fragile X Syndrome | MECP2 Gene Test for Rett Syndrome | Whole Exome Sequencing (WES) | Chromosomal Microarray Analysis |
|---|---|---|---|---|---|
| Comparison | ZCCHC12 Gene Mental retardation non-syndromic NGS Genetic Test | Targets a different genetic cause of intellectual disability with specific features | Focused on a syndromic form of intellectual disability, primarily in females | Broader analysis of multiple genes, may identify variants in ZCCHC12 and others | Detects chromosomal abnormalities, not specific to ZCCHC12 mutations |
Frequently Asked Questions
What is the ZCCHC12 gene test?
Who should consider this test?
How is the sample collected?
Is fasting required for this test?
What is the cost of the test?
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Can this test diagnose other conditions?
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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.
Your Data Privacy
Your medical data is protected under Indian law.
✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.
✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.
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