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DNA Labs India

Acetylcholine Receptor (AChR) Modulating Antibody Test

DNA Labs India | ISO 9001:2015 Certified

Acetylcholine Receptor (AChR) Modulating Antibody Test

Short Name: AChR Modulating Antibody Test

Also known as: AChR Modulating Antibody Test, Acetylcholine Receptor Antibody Test

Acetylcholine Receptor (AChR) Modulating Antibody Test test available at DNA Labs India for ₹24,000. Uses Radiobinding Assay on Serum samples. Results in 2-3 weeks. Free home collection in 300+ cities across India.

Diagnostic TestAdults🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr SHAILAJA RAGHUNATH MURDESHWAR

Dr SHAILAJA RAGHUNATH MURDESHWAR

Consultant Physician · Reg: 8052

Last reviewed: September 7, 2026

Overview

To diagnose myasthenia gravis and other autoimmune neuromuscular disorders by detecting AChR modulating antibodies in the blood.

Test Code
55
Price
₹24,000
Sample Type
Serum
Result Time
2-3 weeks
Fasting Required
No
Method
Radiobinding Assay
Step 1

Sample Collection

Avoid general anaesthetic or muscle relaxant drugs 24 hours prior to sampling. Ensure consent form is filled.

Method: Venipuncture

Step 2

Laboratory Analysis

Standard venipuncture procedure to collect blood sample.

Step 3

Report Delivery

Apply pressure to the puncture site to stop bleeding. Keep the area clean.

Timeline: 2-3 weeks

Patient Instructions

1
Before the Test:Avoid general anaesthetic or muscle relaxant drugs 24 hours prior to sampling. Ensure consent form is filled.
2
During the Test:Standard venipuncture procedure to collect blood sample.
3
After the Test:Apply pressure to the puncture site to stop bleeding. Keep the area clean.

About This Test

Who Should Get This Test

To diagnose myasthenia gravis and other autoimmune neuromuscular disorders by detecting AChR modulating antibodies in the blood.

How to Prepare

  • Avoid general anaesthetic or muscle relaxant drugs 24 hours prior to sampling.
  • Duly filled Test Send Out Consent Form (Form 35) is mandatory.

Doctor's Notes

Reviewed by — MBBS, MD (General Medicine) · Reg. No. 8052

"This test is crucial for diagnosing myasthenia gravis and guiding treatment decisions to improve patient outcomes."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeSerum
Sample Volume2 mL (0.5 mL min.)
ContainerRed Top (No Additive) tube
Collection MethodVenipuncture

Sample Stability

Room Temperature: 8 hours
Refrigerator: 14 days
Frozen: 30 days
Sample Rejection Criteria:
  • Sample collected in incorrect tube
  • Hemolyzed or lipemic samples
  • Missing consent form

Understanding Your Results

Results of the AChR Modulating Antibody Test help in diagnosing myasthenia gravis. A positive result indicates the presence of antibodies that interfere with acetylcholine receptor function.
📊

Positive

Suggestive of myasthenia gravis or other autoimmune neuromuscular disorders. Clinical correlation is recommended.

📊

Negative

No detectable AChR modulating antibodies. Does not completely rule out myasthenia gravis if clinical suspicion remains.

📊

Equivocal

Borderline results may require repeat testing or additional investigations.

⚠️ When to Consult a Doctor:

If test results are positive or if symptoms persist despite negative results, consult a neurologist or immunologist for further evaluation and management.

Limitations

  • ⚠May not detect all cases of myasthenia gravis
  • ⚠False positives can occur in other autoimmune conditions
  • ⚠Test results should be correlated with clinical symptoms

Risks & Considerations

  • ●Minor pain or bruising at the blood draw site
  • ●Rare risk of infection

Interfering Factors

  • ●Use of general anaesthetic or muscle relaxant drugs within 24 hours prior to sampling

Frequently Asked Questions

What is the AChR Modulating Antibody Test?
It is a blood test that measures levels of antibodies against acetylcholine receptors, used to diagnose autoimmune conditions like myasthenia gravis.
Why is this test performed?
To confirm diagnosis of myasthenia gravis or investigate symptoms such as muscle weakness, double vision, and difficulty swallowing.
How is the test conducted?
A blood sample is collected via venipuncture and analyzed using a radiobinding assay to detect AChR modulating antibodies.
What is the cost of the test?
The cost is INR 24000 in India, with home sample collection available at no extra charge.
How long does it take to get results?
Results are typically available within 2-3 weeks after sample collection.
Is home sample collection available?
Yes, free home sample collection is offered for online bookings across many cities in India.
What are the symptoms that indicate this test?
Symptoms include muscle weakness, fatigue, difficulty breathing, double vision, slurred speech, and difficulty swallowing.
How should I prepare for the test?
Avoid general anaesthetic or muscle relaxant drugs 24 hours prior to sampling and ensure the consent form is filled.
What does a positive result mean?
A positive result suggests the presence of AChR modulating antibodies, indicating myasthenia gravis or related disorders.
Can this test be used for other conditions?
It is primarily for myasthenia gravis, but may be relevant for other autoimmune neuromuscular disorders.
Is the test covered by insurance?
Coverage varies by insurance plan; check with your provider. Government schemes like PMJAY may not cover it.
How accurate is the test?
The test is highly accurate when performed correctly, but results should be interpreted alongside clinical symptoms by a specialist.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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